Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling

Identification of Optimal Drug Combinations Targeting Cellular Networks: Integrating Phospho-Proteomics and Computational Network Analysis

(2010) S. Iadevaia et al.   CANCER RESEARCH

Comprehensive Mapping of the Human Kinome to Epidermal Growth Factor Receptor Signaling

(2010) Kakajan Komurov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Use of Data-Biased Random Walks on Graphs for the Retrieval of Context-Specific Networks from Genomic Data

(2010) Kakajan Komurov et al.   PLoS Computational Biology

Rapidly exploring structural and dynamic properties of signaling networks using PathwayOracle

(2008) Derek Ruths et al.   BMC Systems Biology

Feedback Mechanisms Promote Cooperativity for Small Molecule Inhibitors of Epidermal and Insulin-Like Growth Factor Receptors

(2008) E. Buck et al.   CANCER RESEARCH

Growth Inhibition and Radiosensitization of Glioblastoma and Lung Cancer Cells by Small Interfering RNA Silencing of Tumor Necrosis Factor Receptor-Associated Factor 2

(2008) M. Zheng et al.   CANCER RESEARCH

Network topology determines dynamics of the mammalian MAPK1,2 signaling network: bifan motif regulation of C-Raf and B-Raf isoforms by FGFR and MC1R

(2008) Melissa Muller et al.   FASEB JOURNAL

The Signaling Petri Net-Based Simulator: A Non-Parametric Strategy for Characterizing the Dynamics of Cell-Specific Signaling Networks

(2008) Derek Ruths et al.   PLoS Computational Biology