Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells

TGF-β Signaling, Activated Stromal Fibroblasts, and Cysteine Cathepsins B and L Drive the Invasive Growth of Human Melanoma Cells

(2012) Miao Yin et al.   AMERICAN JOURNAL OF PATHOLOGY

Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases

(2012) Yoh Takuwa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Sphingosine-1-phosphate: A Janus-faced mediator of fibrotic diseases

(2012) Stephanie Schwalm et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Role of sphingosine 1-phosphate and lysophosphatidic acid in fibrosis

(2012) Nigel J. Pyne et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

S1PR1-STAT3 Signaling Is Crucial for Myeloid Cell Colonization at Future Metastatic Sites

(2012) Jiehui Deng et al.   CANCER CELL

Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis

(2012) Suriyan Ponnusamy et al.   EMBO Molecular Medicine

Sphingosine kinase 1 enhances colon cancer cell proliferation and invasion by upregulating the production of MMP-2/9 and uPA via MAPK pathways

(2012) Shi-Quan Liu et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Oncogenic K-Ras Regulates Bioactive Sphingolipids in a Sphingosine Kinase 1-dependent Manner

(2012) Christopher R. Gault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A brief history of melanoma

(2012) Vito W. Rebecca et al.   MELANOMA RESEARCH

Targeting sphingosine kinase-1 to inhibit melanoma

(2012) SubbaRao V. Madhunapantula et al.   Pigment Cell & Melanoma Research

Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression

(2011) Paolo Cirri et al.   CANCER AND METASTASIS REVIEWS

Fibroblasts Contribute to Melanoma Tumor Growth and Drug Resistance

(2011) Edward H. Flach et al.   MOLECULAR PHARMACEUTICS

Sphingosine-1-phosphate signaling and its role in disease

(2011) Michael Maceyka et al.   TRENDS IN CELL BIOLOGY

Sphingosine 1-phosphate (S1P)/S1P receptors are involved in human liver fibrosis by action on hepatic myofibroblasts motility

(2010) Changyong Li et al.   JOURNAL OF HEPATOLOGY

Disruption of Sphingosine 1-Phosphate Lyase Confers Resistance to Chemotherapy and Promotes Oncogenesis through Bcl-2/Bcl-xL Upregulation

(2009) S. Colie et al.   CANCER RESEARCH

Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor- -stimulated collagen production by cardiac fibroblasts

(2009) N. Gellings Lowe et al.   CARDIOVASCULAR RESEARCH

Sphingosine Kinase1 Is Pivotal for Fc RI-Mediated Mast Cell Signaling and Functional Responses In Vitro and In Vivo

(2009) P. N. Pushparaj et al.   JOURNAL OF IMMUNOLOGY

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression

(2009) Masayuki Shimoda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

New players on the center stage: Sphingosine 1-phosphate and its receptors as drug targets

(2008) Andrea Huwiler et al.   BIOCHEMICAL PHARMACOLOGY

Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularization

(2008) Sergio Caballero et al.   EXPERIMENTAL EYE RESEARCH

Indium-111–Pentetreotide Scintigraphy and Somatostatin Receptor Subtype 2 Expression: New Prognostic Factors for Malignant Well-Differentiated Endocrine Tumors

(2008) Amani Asnacios et al.   JOURNAL OF CLINICAL ONCOLOGY

K6PC-5, a sphingosine kinase activator, induces anti-aging effects in intrinsically aged skin through intracellular Ca2+ signaling

(2008) Jong-Kyung Youm et al.   JOURNAL OF DERMATOLOGICAL SCIENCE