5-Fluorouracil signaling through a calcium–calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells

A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX

(2012) Ryan E Henry et al.   EMBO JOURNAL

How phosphorylation controls p53

(2011) Nicola J. Maclaine et al.   CELL CYCLE

Caspases and cancer

(2011) M Olsson et al.   CELL DEATH AND DIFFERENTIATION

Aberrant ribosome biogenesis activates c-Myc and ASK1 pathways resulting in p53-dependent G1 arrest

(2011) H D Kim et al.   ONCOGENE

P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance

(2011) M A de la Cruz-Morcillo et al.   ONCOGENE

ATM kinase activity modulates cFLIP protein levels: potential interplay between DNA damage signalling and TRAIL-induced apoptosis

(2010) Venturina Stagni et al.   CARCINOGENESIS

Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes

(2010) C Oberle et al.   CELL DEATH AND DIFFERENTIATION

TRAIL receptor signaling and therapeutics

(2010) Junaid Abdulghani et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Chemotherapeutic Drugs Inhibit Ribosome Biogenesis at Various Levels

(2010) Kaspar Burger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ATM Inhibitor KU-55933 Suppresses Cell Proliferation and Induces Apoptosis by Blocking Akt In Cancer Cells with Overactivated Akt

(2010) Y. Li et al.   MOLECULAR CANCER THERAPEUTICS

Apoptosis and Autophagy: Decoding Calcium Signals that Mediate Life or Death

(2010) M. W. Harr et al.   Cold Spring Harbor Perspectives in Biology

Differential regulation of p53 function by protein kinase C isoforms revealed by a yeast cell system

(2009) Isabel Coutinho et al.   FEBS LETTERS

Cellular FLICE-inhibitory protein (c-FLIP) signalling: A key regulator of receptor-mediated apoptosis in physiologic context and in cancer

(2009) Marina Bagnoli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

5-Fluorouracil and its active metabolite FdUMP cause DNA damage in human SW620 colon adenocarcinoma cell line

(2009) Renata Matuo et al.   JOURNAL OF APPLIED TOXICOLOGY

DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis

(2009) M Olsson et al.   ONCOGENE

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE