P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance

Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controls

(2014) Isei Tanida et al.   Autophagy

A dual role of p53 in the control of autophagy

(2014) Ezgi Tasdemir et al.   Autophagy

Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics

(2011) Tracey R. O’Donovan et al.   Autophagy

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Stimulation of autophagy by the p53 target gene Sestrin2

(2010) Maria Chiara Maiuri et al.   CELL CYCLE

BNIP3 is essential for mediating 6-thioguanine- and 5-fluorouracil-induced autophagy following DNA mismatch repair processing

(2010) Xuehuo Zeng et al.   CELL RESEARCH

Autophagy regulation by p53

(2010) Maria Chiara Maiuri et al.   CURRENT OPINION IN CELL BIOLOGY

Advances in the systemic treatment of head and neck cancers

(2010) Pol Specenier et al.   CURRENT OPINION IN ONCOLOGY

Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model

(2010) Jie Li et al.   EUROPEAN JOURNAL OF CANCER

Inhibition of phosphatidylinositol 3-kinase promotes tumor cell resistance to chemotherapeutic agents via a mechanism involving delay in cell cycle progression

(2010) Gail T. McDonald et al.   EXPERIMENTAL CELL RESEARCH

The ATM Inhibitor KU-55933 Suppresses Cell Proliferation and Induces Apoptosis by Blocking Akt In Cancer Cells with Overactivated Akt

(2010) Y. Li et al.   MOLECULAR CANCER THERAPEUTICS

DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization

(2010) H. Christian Reinhardt et al.   MOLECULAR CELL

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

p53 post-translational modification: deregulated in tumorigenesis

(2010) Chao Dai et al.   TRENDS IN MOLECULAR MEDICINE

p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting

(2009) J. M. McClung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer Cells

(2009) Jie Li et al.   ANNALS OF SURGICAL ONCOLOGY

Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell

(2009) Hai-yan Xiong et al.   CANCER LETTERS

Coordinated regulation of autophagy by p38α MAPK through mAtg9 and p38IP

(2009) Jemma L Webber et al.   EMBO JOURNAL

Modulation of intracellular ROS levels by TIGAR controls autophagy

(2009) Karim Bensaad et al.   EMBO JOURNAL

Capecitabine and vinorelbine in metastatic breast cancer

(2009) Arlene Chan et al.   EUROPEAN JOURNAL OF CANCER

p38 Mitogen-Activated Protein Kinase- and HuR-Dependent Stabilization of p21Cip1 mRNA Mediates the G1/S Checkpoint

(2009) V. Lafarga et al.   MOLECULAR AND CELLULAR BIOLOGY

Reduced ATR or Chk1 Expression Leads to Chromosome Instability and Chemosensitization of Mismatch Repair–deficient Colorectal Cancer Cells

(2009) Melanie J. Jardim et al.   MOLECULAR BIOLOGY OF THE CELL

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Molecular Basis for the Induction of an Angiogenesis Inhibitor, Thrombospondin-1, by 5-Fluorouracil

(2008) H.-Y. Zhao et al.   CANCER RESEARCH

ATM and the Mre11-Rad50-Nbs1 Complex Respond to Nucleoside Analogue-Induced Stalled Replication Forks and Contribute to Drug Resistance

(2008) B. Ewald et al.   CANCER RESEARCH

Participation of DNA repair in the response to 5-fluorouracil

(2008) M. D. Wyatt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

E1aGene Expression Blocks the ERK1/2 Signaling Pathway by Promoting Nuclear Localization and MKP Up-regulation

(2008) Juan L. Callejas-Valera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATR-dependent Activation of p38 MAP Kinase Is Responsible for Apoptotic Cell Death in Cells Depleted of Cdc7

(2008) Jun-Sub Im et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine

(2008) Angen Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY

Nucleoside analogs: molecular mechanisms signaling cell death

(2008) B Ewald et al.   ONCOGENE

Critical Involvement of the ATM-Dependent DNA Damage Response in the Apoptotic Demise of HIV-1-Elicited Syncytia

(2008) Jean-Luc Perfettini et al.   PLoS One

Inhibition of p38 MAPK Suppresses Inflammatory Cytokine Induction by Etoposide, 5-Fluorouracil, and Doxorubicin without Affecting Tumoricidal Activity

(2008) Collin R. Elsea et al.   PLoS One

Colon Cancer in Older Adults

(2008) Laura Raftery et al.   SEMINARS IN ONCOLOGY