Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein

Oncogenic AKTivation of translation as a therapeutic target

(2011) A C Hsieh et al.   BRITISH JOURNAL OF CANCER

Tumor Suppressor Protein Pdcd4 Inhibits Translation of p53 mRNA

(2011) Lena Wedeken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma

(2011) Jonathan H. Schatz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Synthesis of Rocaglamide Hydroxamates and Related Compounds as Eukaryotic Translation Inhibitors: Synthetic and Biological Studies

(2011) Christina M. Rodrigo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dependence on the MUC1-C Oncoprotein in Non-Small Cell Lung Cancer Cells

(2011) D. Raina et al.   MOLECULAR CANCER THERAPEUTICS

Mucin 1 C-Terminal Subunit Oncoprotein Is a Target for Small-Molecule Inhibitors

(2011) Y. Zhou et al.   MOLECULAR PHARMACOLOGY

The biological and therapeutic relevance of mRNA translation in cancer

(2011) Sarah P. Blagden et al.   Nature Reviews Clinical Oncology

mRNA helicases: the tacticians of translational control

(2011) Armen Parsyan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MUC1-C Oncoprotein Promotes STAT3 Activation in an Autoinductive Regulatory Loop

(2011) R. Ahmad et al.   Science Signaling

Drugging the PI3 Kinome: From Chemical Tools to Drugs in the Clinic

(2010) P. Workman et al.   CANCER RESEARCH

The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo

(2009) David M. Lucas et al.   BLOOD

MUC1-C Oncoprotein Functions as a Direct Activator of the Nuclear Factor- B p65 Transcription Factor

(2009) R. Ahmad et al.   CANCER RESEARCH

Direct Targeting of the Mucin 1 Oncoprotein Blocks Survival and Tumorigenicity of Human Breast Carcinoma Cells

(2009) D. Raina et al.   CANCER RESEARCH

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

Advances in Development of Phosphatidylinositol 3-Kinase Inhibitors

(2009) Dexin Kong et al.   CURRENT MEDICINAL CHEMISTRY

MUC1 oncoprotein is a druggable target in human prostate cancer cells

(2009) M. D. Joshi et al.   MOLECULAR CANCER THERAPEUTICS

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Antitumor Activity and Mechanism of Action of the Cyclopenta[b]benzofuran, Silvestrol

(2009) Regina Cencic et al.   PLoS One