Oncogenic E17K mutation in the pleckstrin homology domain of AKT1 promotes v-Abl-mediated pre-B-cell transformation and survival of Pim-deficient cells

AKT1 (E17K) Mutation in Pancreatic Cancer

(2014) Azim Mohamedali et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

Activating E17K mutation in the gene encoding the protein kinase AKT in a subset of squamous cell carcinoma of the lung

(2010) Donatella Malanga et al.   CELL CYCLE

The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas

(2009) K Shoji et al.   BRITISH JOURNAL OF CANCER

AKT1 E17 K pleckstrin homology domain mutation in urothelial carcinoma

(2009) Dorit E. Zilberman et al.   CANCER GENETICS AND CYTOGENETICS

Inhibition of vimentin or  1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo

(2009) X. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

AKT1 mutations in bladder cancer: identification of a novel oncogenic mutation that can co-operate with E17K

(2009) J M Askham et al.   ONCOGENE

Molecular Mechanism of an Oncogenic Mutation That Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of the AKT1 PH Domain†

(2008) Kyle E. Landgraf et al.   BIOCHEMISTRY

Analysis of oncogenic AKT1 p.E17K mutation in carcinomas of the biliary tract and liver

(2008) M-O Riener et al.   BRITISH JOURNAL OF CANCER

The transforming mutation E17K/AKT1 is not a major event in B-cell-derived lymphoid leukaemias

(2008) I S Mahmoud et al.   BRITISH JOURNAL OF CANCER

Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias

(2008) M S Kim et al.   BRITISH JOURNAL OF CANCER

Chronic lymphocytic leukaemia and acute myeloid leukaemia are not associated with AKT1 pleckstrin homology domain (E17K) mutations

(2008) T. Zenz et al.   BRITISH JOURNAL OF HAEMATOLOGY

Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells

(2008) Michael G. Kharas et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells

(2008) S Horn et al.   ONCOGENE

AKT1 E17K in human solid tumours

(2008) F E Bleeker et al.   ONCOGENE