Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation

Restoration of p53 to limit tumor growth

(2009) Wenge Wang et al.   CURRENT OPINION IN ONCOLOGY

The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression

(2008) E. Shema et al.   GENES & DEVELOPMENT

LATS2 tumour specific mutations and down-regulation of the gene in non-small cell carcinoma

(2008) Mojca Stražišar et al.   LUNG CANCER

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

The genetics of the p53 pathway, apoptosis and cancer therapy

(2008) Alexei Vazquez et al.   NATURE REVIEWS DRUG DISCOVERY

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE