Glucose-dependent insulinotropic polypeptide: from pathophysiology to therapeutic opportunities in obesity-associated disorders

Effect of ezetimibe on incretin secretion in response to the intestinal absorption of a mixed meal

(2010) Li Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Physiologic and Pharmacologic Modulation of Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Expression in  -Cells by Peroxisome Proliferator-Activated Receptor (PPAR)-  Signaling: Possible Mechanism for the GIP Resistance in Type 2 Diabetes

(2010) D. Gupta et al.   DIABETES

Glucose-Dependent Insulinotropic Polypeptide May Enhance Fatty Acid Re-esterification in Subcutaneous Abdominal Adipose Tissue in Lean Humans

(2010) M. Asmar et al.   DIABETES

Minireview: Update on Incretin Biology: Focus on Glucagon-Like Peptide-1

(2010) Patricia L. Brubaker   ENDOCRINOLOGY

GPR119 Regulates Murine Glucose Homeostasis Through Incretin Receptor-Dependent and Independent Mechanisms

(2010) Grace Flock et al.   ENDOCRINOLOGY

Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin

(2010) Jeannine Sauber et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes

(2010) Katharina Timper et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

GIP and Bariatric Surgery

(2010) Raghavendra S. Rao et al.   OBESITY SURGERY

Glucose-dependent insulinotropic polypeptide stimulates the proliferation of colorectal cancer cells

(2010) Daniel Prabakaran et al.   REGULATORY PEPTIDES

Prolonged saturated fat–induced, glucose-dependent insulinotropic polypeptide elevation is associated with adipokine imbalance and liver injury in nonalcoholic steatohepatitis: dysregulated enteroadipocyte axis as a novel feature of fatty liver

(2009) Giovanni Musso et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

RS4-type resistant starch prevents high-fat diet-induced obesity via increased hepatic fatty acid oxidation and decreased postprandial GIP in C57BL/6J mice

(2009) Akira Shimotoyodome et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans

(2009) Meena Asmar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects

(2009) Jing Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups

(2009) Carla IG Vogel et al.   BMC Medical Genetics

Effects of peripheral administration of synthetic human glucose-dependent insulinotropic peptide (GIP) on energy expenditure and subjective appetite sensations in healthy normal weight subjects and obese patients with type 2 diabetes

(2009) C. Daousi et al.   CLINICAL ENDOCRINOLOGY

Thiazolidinediones in prediabetes and early type 2 diabetes: What can be learned about that disease’s pathogenesis

(2009) Jack L. Leahy   Current Diabetes Reports

GPR40: Good Cop, Bad Cop?

(2009) T. Alquier et al.   DIABETES

TCF7L2 Variant rs7903146 Affects the Risk of Type 2 Diabetes by Modulating Incretin Action

(2009) D. T. Villareal et al.   DIABETES

Exogenous Glucose-Dependent Insulinotropic Polypeptide Worsens Post prandial Hyperglycemia in T ype 2 Diabetes

(2009) C. W. Chia et al.   DIABETES

GPR119 Is Essential for Oleoylethanolamide-Induced Glucagon-Like Peptide-1 Secretion From the Intestinal Enteroendocrine L-Cell

(2009) L. M. Lauffer et al.   DIABETES

WNT/β-catenin increases the production of incretins by entero-endocrine cells

(2009) J. M. García-Martínez et al.   DIABETOLOGIA

Coingestion of Acylglycerols Differentially Affects Glucose-Induced Insulin Secretion via Glucose-Dependent Insulinotropic Polypeptide in C57BL/6J Mice

(2009) Akira Shimotoyodome et al.   ENDOCRINOLOGY

Secretion and Dipeptidyl Peptidase-4-Mediated Metabolism of Incretin Hormones after a Mixed Meal or Glucose Ingestion in Obese Compared to Lean, Nondiabetic Men

(2009) Richard D. Carr et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

GPR119 is required for physiological regulation of glucagon-like peptide-1 secretion but not for metabolic homeostasis

(2009) Hong Lan et al.   JOURNAL OF ENDOCRINOLOGY

Exercise prior to fat ingestion lowers fasting and postprandial VLDL and decreases adipose tissue IL-6 and GIP receptor mRNA in hypertriacylglycerolemic men

(2009) Mark J. Dekker et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of meal size and composition on incretin, α-cell, and β-cell responses

(2009) Josina M. Rijkelijkhuizen et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Intracerebroventricular infusion of bombesin modulates GIP secretion in conscious dogs

(2009) Maria P. Yavropoulou et al.   NEUROPHARMACOLOGY

Effect of intracerebroventricular infusion of insulin on glucose-dependent insulinotropic peptide in dogs

(2009) Maria P. Yavropoulou et al.   NEUROSCIENCE LETTERS

Obesity, the PI3K/Akt signal pathway and colon cancer

(2009) X-F. Huang et al.   Obesity Reviews

Effect of intracerebroventricular infusion of neurotensin in glucose-dependent insulinotropic peptide secretion in dogs

(2009) Maria P. Yavropoulou et al.   PEPTIDES

Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo

(2008) Yukihiro Fujita et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Using the lymph fistula rat model to study the potentiation of GIP secretion by the ingestion of fat and glucose

(2008) Wendell J. Lu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Orlistat accelerates gastric emptying and attenuates GIP release in healthy subjects

(2008) Feruze Yılmaz Enç et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Glucose Sensing in L Cells: A Primary Cell Study

(2008) Frank Reimann et al.   Cell Metabolism

The Fatty Acid Receptor GPR40 Plays a Role in Insulin Secretion In Vivo After High-Fat Feeding

(2008) M. Kebede et al.   DIABETES

Gpr40 Is Expressed in Enteroendocrine Cells and Mediates Free Fatty Acid Stimulation of Incretin Secretion

(2008) S. Edfalk et al.   DIABETES

WNT signalling is both an inducer and effector of glucagon-like peptide-1

(2008) B. Gustafson et al.   DIABETOLOGIA

Pathogenesis of type 2 diabetes: tracing the reverse route from cure to cause

(2008) R. Taylor   DIABETOLOGIA

Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells

(2008) H. E. Parker et al.   DIABETOLOGIA

A Role for Intestinal Endocrine Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Peptide Release

(2008) Zhi-Liang Chu et al.   ENDOCRINOLOGY

Insulin Regulates Glucagon-Like Peptide-1 Secretion from the Enteroendocrine L Cell

(2008) Gareth E. Lim et al.   ENDOCRINOLOGY

High saturated-fat diet induces apoptosis in rat enterocytes and blunts GIP and insulin-secretive response to oral glucose load

(2008) D Gniuli et al.   INTERNATIONAL JOURNAL OF OBESITY

Functional expression of glucose-dependent insulinotropic polypeptide receptors is coupled to differentiation in a human adipocyte model

(2008) R E Weaver et al.   INTERNATIONAL JOURNAL OF OBESITY

Targeted Ablation of Glucose-dependent Insulinotropic Polypeptide-producing Cells in Transgenic Mice Reduces Obesity and Insulin Resistance Induced by a High Fat Diet

(2008) Matthew C. Althage et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Weight Loss by Gastric Bypass SurgeryVersusHypocaloric Diet on Glucose and Incretin Levels in Patients with Type 2 Diabetes

(2008) Blandine Laferrère et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Orlistat Inhibition of Intestinal Lipase Acutely Increases Appetite and Attenuates Postprandial Glucagon-Like Peptide-1-(7–36)-Amide-1, Cholecystokinin, and Peptide YY Concentrations

(2008) Mark Ellrichmann et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Intracerebroventricular infusion of neuropeptide Y increases glucose dependent-insulinotropic peptide secretion in the fasting conscious dog

(2008) Maria P. Yavropoulou et al.   PEPTIDES

The entero-insular axis: implications for human metabolism

(2007) Lakshminarayan R. Ranganath   CLINICAL CHEMISTRY AND LABORATORY MEDICINE