The Renin-Angiotensin System in the Pathophysiology of Type 2 Diabetes

Valsartan Improves Adipose Tissue Function in Humans with Impaired Glucose Metabolism: A Randomized Placebo-Controlled Double-Blind Trial

(2012) Gijs H. Goossens et al.   PLoS One

Chronic renin inhibition with aliskiren improves glucose tolerance, insulin sensitivity, and skeletal muscle glucose transport activity in obese Zucker rats

(2011) Elizabeth M. Marchionne et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Increased Adipose Tissue Oxygen Tension in Obese Compared With Lean Men Is Accompanied by Insulin Resistance, Impaired Adipose Tissue Capillarization, and Inflammation

(2011) Gijs H. Goossens et al.   CIRCULATION

Valsartan Improves  -Cell Function and Insulin Sensitivity in Subjects With Impaired Glucose Metabolism: A randomized controlled trial

(2011) N. J. van der Zijl et al.   DIABETES CARE

Aliskiren improves insulin resistance and ameliorates diabetic vascular complications in db/db mice

(2011) Young Sun Kang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance

(2010) Hui-Young Lee et al.   Cell Metabolism

Effect of Renin-Angiotensin System Blockade on Insulin Resistance and Inflammatory Parameters in Patients With Impaired Glucose Tolerance

(2010) S. Pscherer et al.   DIABETES CARE

Valsartan Protects Pancreatic Islets and Adipose Tissue From the Inflammatory and Metabolic Consequences of a High-Fat Diet in Mice

(2010) Banumathi K. Cole et al.   HYPERTENSION

Direct renin inhibition improved insulin resistance and adipose tissue dysfunction in type 2 diabetic KK-Ay mice

(2010) Masaru Iwai et al.   JOURNAL OF HYPERTENSION

Effect of Valsartan on the Incidence of Diabetes and Cardiovascular Events

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial dysfunction and lipotoxicity

(2009) Patrick Schrauwen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Effect of Rosiglitazone and Ramipril on  -Cell Function in People With Impaired Glucose Tolerance or Impaired Fasting Glucose: The DREAM trial

(2009) A. J. Hanley et al.   DIABETES CARE

The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action

(2009) E. J. Barrett et al.   DIABETOLOGIA

Direct Renin Inhibition Improves Systemic Insulin Resistance and Skeletal Muscle Glucose Transport in a Transgenic Rodent Model of Tissue Renin Overexpression

(2009) Guido Lastra et al.   ENDOCRINOLOGY

Blockade of the RAS increases Plasma Adiponectin in Subjects with Metabolic Syndrome and Enhances Differentiation and Adiponectin Expression of Human Preadipocytes

(2009) FS. Tian et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Angiotensin II Type 1 and Type 2 Receptors Regulate Basal Skeletal Muscle Microvascular Volume and Glucose Use

(2009) Weidong Chai et al.   HYPERTENSION

Effects of Antihypertensive Drugs on Capillary Rarefaction in Spontaneously Hypertensive Rats: Intravital Microscopy and Histologic Analysis

(2009) Bruno Sabino et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Angiotensin receptor blockers improve insulin signaling and prevent microvascular rarefaction in the skeletal muscle of spontaneously hypertensive rats

(2009) Damiano Rizzoni et al.   JOURNAL OF HYPERTENSION

Long-term treatment with an angiotensin II receptor blocker decreases adipocyte size and improves insulin signaling in obese Zucker rats

(2009) Marina C Muñoz et al.   JOURNAL OF HYPERTENSION

Blockade of AT1 Receptor Improves Adipocyte Differentiation in Atherosclerotic and Diabetic Models

(2008) Y. Tomono et al.   AMERICAN JOURNAL OF HYPERTENSION

Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat

(2008) Guido Lastra et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Improved Early-Phase Insulin Response after Candesartan Treatment in Hypertensive Patients with Impaired Glucose Tolerance

(2008) Katsunori Suzuki et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Angiotensin II Reduces Mitochondrial Content in Skeletal Muscle and Affects Glycemic Control

(2008) M. Mitsuishi et al.   DIABETES

Reduced Adipose Tissue Oxygenation in Human Obesity: Evidence for Rarefaction, Macrophage Chemotaxis, and Inflammation Without an Angiogenic Response

(2008) M. Pasarica et al.   DIABETES

Inhibiting angiotensin type 1 receptors as a target for diabetes

(2008) Ulrich Kintscher et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Angiotensin receptor blockers improve insulin resistance in type 2 diabetic rats by modulating adipose tissue

(2008) Mi H. Lee et al.   KIDNEY INTERNATIONAL

Suppression of lipoprotein lipase expression in 3T3-L1 cells by inhibition of adipogenic differentiation through activation of the renin-angiotensin system

(2008) Atsuhito Saiki et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Angiotensin II and the development of insulin resistance: Implications for diabetes

(2008) J. Alberto Olivares-Reyes et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

MEDICINE: Can We Nip Obesity in Its Vascular Bud?

(2008) C. R. Kahn   SCIENCE

Angiotensin II-induced skeletal muscle insulin resistance mediated by NF-κB activation via NADPH oxidase

(2007) Yongzhong Wei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance

(2007) Gijs H. Goossens   PHYSIOLOGY & BEHAVIOR