Leucine as a pharmaconutrient to prevent and treat sarcopenia and type 2 diabetes

Exercising before protein intake allows for greater use of dietary protein–derived amino acids for de novo muscle protein synthesis in both young and elderly men

(2010) Bart Pennings et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Long-term effects of leucine supplementation on body composition

(2010) Michèle Balage et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The impact of sarcopenia and exercise training on skeletal muscle satellite cells

(2009) Tim Snijders et al.   AGEING RESEARCH REVIEWS

Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men

(2009) Suzanne Verhoeven et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Prevalence of daily hyperglycemia in obese type 2 diabetic men compared with that in lean and obese normoglycemic men: effect of consumption of a sucrose-containing beverage

(2009) Ralph JF Manders et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Blunting of insulin inhibition of proteolysis in legs of older subjects may contribute to age-related sarcopenia

(2009) Emilie A Wilkes et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes

(2009) S. W. Park et al.   DIABETES CARE

Amino Acid Supplementation Increases Lean Body Mass, Basal Muscle Protein Synthesis, and Insulin-Like Growth Factor-I Expression in Older Women

(2009) Edgar L. Dillon et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Dietary Protein Digestion and Absorption Rates and the Subsequent Postprandial Muscle Protein Synthetic Response Do Not Differ between Young and Elderly Men

(2009) René Koopman et al.   JOURNAL OF NUTRITION

Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle

(2008) P. L. Greenhaff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Amino acids are necessary for the insulin-induced activation of mTOR/S6K1 signaling and protein synthesis in healthy and insulin resistant human skeletal muscle

(2008) Micah J. Drummond et al.   CLINICAL NUTRITION

Effect of amino acid supplementation on muscle mass, strength and physical function in elderly

(2008) Elisabet Børsheim et al.   CLINICAL NUTRITION

Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men

(2008) Vinod Kumar et al.   JOURNAL OF PHYSIOLOGY-LONDON

mVps34 is activated following high-resistance contractions

(2008) Matthew G. MacKenzie et al.   JOURNAL OF PHYSIOLOGY-LONDON

Regulation of TORC1 by Rag GTPases in nutrient response

(2008) Eunjung Kim et al.   NATURE CELL BIOLOGY

Amino acid supplementation decreases plasma and liver triacylglycerols in elderly

(2008) Elisabet Børsheim et al.   NUTRITION

Leucine and Protein Synthesis: mTOR and Beyond

(2008) Martha H. Stipanuk   NUTRITION REVIEWS

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE

Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle

(2007) Hans C. Dreyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Resistance training alters the response of fed state mixed muscle protein synthesis in young men

(2007) Jason E. Tang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY