Flavonoid-Enriched Apple Fraction AF4 Induces Cell Cycle Arrest, DNA Topoisomerase II Inhibition, and Apoptosis in Human Liver Cancer HepG2 Cells

Oligosaccharide from apple induces apoptosis and cell cycle arrest in HT29 human colon cancer cells

(2013) Qian Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Mechanisms of apple polyphenols-induced proliferation inhibiting and apoptosis in a metastatic oral adenoid cystic carcinoma cell line

(2012) Chao-Qun Zheng et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Neuroprotective and Anti-Inflammatory Effects of the Flavonoid-Enriched Fraction AF4 in a Mouse Model of Hypoxic-Ischemic Brain Injury

(2012) Paul G. W. Keddy et al.   PLoS One

A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells

(2011) Nabanita Patra et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli

(2011) Joan Fernando et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Native Australian Fruit Polyphenols Inhibit Cell Viability and Induce Apoptosis in Human Cancer Cell Lines

(2011) Aaron Tan et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Phenolic-Containing Organic Extracts of Mulberry (Morus alba L.) Leaves Inhibit HepG2 Hepatoma Cells Through G2/M Phase Arrest, Induction of Apoptosis, and Inhibition of Topoisomerase IIα Activity

(2010) Wanlaya Naowaratwattana et al.   JOURNAL OF MEDICINAL FOOD

Dietary Polyphenols as Topoisomerase II Poisons: B Ring and C Ring Substituents Determine the Mechanism of Enzyme-Mediated DNA Cleavage Enhancement

(2008) Omari J. Bandele et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Apple Phytochemical Extracts Inhibit Proliferation of Estrogen-Dependent and Estrogen-Independent Human Breast Cancer Cells through Cell Cycle Modulation

(2008) Jie Sun et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Fresh Apples Suppress Mammary Carcinogenesis and Proliferative Activity and Induce Apoptosis in Mammary Tumors of the Sprague−Dawley Rat

(2008) Jia-Ren Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY