Novel 5-Arylcarbamoyl-2-methylisoxazolidin-3-yl-3-phosphonates as Nucleotide Analogues

Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a carbamoyl linker

(2013) Kamil Kokosza et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Truncated phosphonated C-1′-branched N,O-nucleosides: A new class of antiviral agents

(2012) Roberto Romeo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A sulfoximine-based inhibitor of human asparagine synthetase kills l-asparaginase-resistant leukemia cells

(2012) Hideyuki Ikeuchi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The synthesis and antituberculosis activity of 5′-nor carbocyclic uracil derivatives

(2012) Elena Matyugina et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides

(2012) John D. Williams et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and SAR of geminal substitutions at the C5′ carbosugar position of pyrimidine-derived HCV inhibitors

(2012) Vishal A. Verma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Fluorophosphonylated Nucleoside Derivatives as New Series of Thymidine Phosphorylase Multisubstrate Inhibitors

(2012) Sonia Amel Diab et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Pharmacological Evaluation of Dual Acting Antioxidant A2A Adenosine Receptor Agonists

(2012) Nicholas E. Hausler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Biological Evaluation of Fatty Acyl Ester Derivatives of (−)-2′,3′-Dideoxy-3′-thiacytidine

(2012) Hitesh K. Agarwal et al.   JOURNAL OF MEDICINAL CHEMISTRY

Stereoselective Synthesis and Antiviral Activity of Methyl-Substituted cycloSal-Pronucleotides

(2012) Edwuin H. Rios Morales et al.   JOURNAL OF MEDICINAL CHEMISTRY

Optimization of Adenosine 5′-Carboxamide Derivatives as Adenosine Receptor Agonists Using Structure-Based Ligand Design and Fragment Screening

(2012) Dilip K. Tosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Novel N-Branched Acyclic Nucleoside Phosphonates As Potent and Selective Inhibitors of Human, Plasmodium falciparum and Plasmodium vivax 6-Oxopurine Phosphoribosyltransferases

(2012) Dana Hocková et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fluorocyclopentenyl-cytosine with Broad Spectrum and Potent Antitumor Activity

(2012) Won Jun Choi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Sequence and linker dependent chiral dimerization of DNA–porphyrin conjugates

(2012) Gevorg Sargsyan et al.   TETRAHEDRON

Design, Synthesis and Cytotoxicity of a New Series of Isoxazolidine Based Nucleoside Analogues

(2011) Dorota G. Piotrowska et al.   ARCHIV DER PHARMAZIE

Synthesis, SAR, and preliminary mechanistic evaluation of novel antiproliferative N6,5′-bis-ureido- and 5′-carbamoyl-N6-ureidoadenosine derivatives

(2011) Jadd R. Shelton et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Efficient microwave-assisted synthesis, antibacterial activity and high fluorescence of 5 benzimidazolyl-2′-deoxyuridines

(2011) Jamal Krim et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antimycobacterial activities of 5-alkyl (or halo)-3′-substituted pyrimidine nucleoside analogs

(2011) Naveen C. Srivastav et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker

(2011) Dorota G. Piotrowska et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of diastereoisomerically pure N,O-nucleosides

(2010) Olga Bortolini et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2′-deoxyuridines

(2010) Sun Min Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chemical Synthesis of Heterocyclic−Sugar Nucleoside Analogues

(2010) Giovanni Romeo et al.   CHEMICAL REVIEWS

Antiretroviral drugs

(2010) Erik De Clercq   CURRENT OPINION IN PHARMACOLOGY

Synthesis of C-4′Truncated Phosphonated Carbocyclic 2′-Oxa-3′-azanucleosides as Antiviral Agents

(2010) Anna Piperno et al.   JOURNAL OF ORGANIC CHEMISTRY

Exploration of click reaction for the synthesis of modified nucleosides as chitin synthase inhibitors

(2009) Preeti M. Chaudhary et al.   BIOORGANIC & MEDICINAL CHEMISTRY

C5-Modified nucleosides exhibiting anticancer activity

(2009) Yoon-Suk Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

C-Nucleosides: Synthetic Strategies and Biological Applications

(2009) Michal Hocek   CHEMICAL REVIEWS

Synthesis and in vitro cytostatic activity of new β - d -arabino furan[1′,2′:4,5]oxazolo- and arabino-pyrimidinone derivatives

(2009) Jean-Jacques Bosc et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Highlights in the Discovery of Antiviral Drugs: A Personal Retrospective

(2009) Erik De Clercq   JOURNAL OF MEDICINAL CHEMISTRY

Prodrugs of Phosphates and Phosphonates

(2008) Scott J. Hecker et al.   JOURNAL OF MEDICINAL CHEMISTRY