The prion protein is critical for DNA repair and cell survival after genotoxic stress

Vascular-derived TGF-β increases in the stem cell niche and perturbs neurogenesis during aging and following irradiation in the adult mouse brain

(2013) Jose R. Pineda et al.   EMBO Molecular Medicine

Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage

(2013) Clara M.O. Jalland et al.   FREE RADICAL BIOLOGY AND MEDICINE

Prion protein (PrPc) interacts with histone H3 confirmed by affinity chromatography

(2013) Hanning Cai et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Cellular prion protein localizes to the nucleus of endocrine and neuronal cells and interacts with structural chromatin components

(2011) Alexander Strom et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Conserved Stress-protective Activity between Prion Protein and Shadoo

(2011) Vignesh Sakthivelu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of nucleic acid chaperoning by the prion protein and its inhibition by oligonucleotides

(2011) Cécile Guichard et al.   NUCLEIC ACIDS RESEARCH

The N-Terminal, Polybasic Region Is Critical for Prion Protein Neuroprotective Activity

(2011) Jessie A. Turnbaugh et al.   PLoS One

Prion protein at the crossroads of physiology and disease

(2011) Emiliano Biasini et al.   TRENDS IN NEUROSCIENCES

The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death

(2010) En Huang et al.   NATURE CELL BIOLOGY

Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions

(2010) Damiano Fantini et al.   NUCLEIC ACIDS RESEARCH

Cell Type-Specific Neuroprotective Activity of Untranslocated Prion Protein

(2010) Elena Restelli et al.   PLoS One

Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia

(2010) R. A. Stetler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights into cellular prion protein (PrPc) functions: The “ying and yang” of a relevant protein

(2009) Oriol Nicolas et al.   BRAIN RESEARCH REVIEWS

Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice

(2009) Archana Unnikrishnan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway

(2009) Y.-S. Kang et al.   JOURNAL OF CELL SCIENCE

APE1/Ref-1 Interacts with NPM1 within Nucleoli and Plays a Role in the rRNA Quality Control Process

(2009) C. Vascotto et al.   MOLECULAR AND CELLULAR BIOLOGY

Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair

(2008) Wen-Cheng Chou et al.   EMBO JOURNAL

Biosynthesis of Prion Protein Nucleocytoplasmic Isoforms by Alternative Initiation of Translation

(2008) María E. Juanes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATM-mediated Transcriptional Elevation of Prion in Response to Copper-induced Oxidative Stress

(2008) Kefeng Qin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay

(2008) Ola Söderberg et al.   METHODS

Protein microarray analysis identifies human cellular prion protein interactors

(2008) J. Satoh et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Physiology of the Prion Protein

(2008) Rafael Linden et al.   PHYSIOLOGICAL REVIEWS

The Cellular Prion Protein PrPc Is Involved in the Proliferation of Epithelial Cells and in the Distribution of Junction-Associated Proteins

(2008) Etienne Morel et al.   PLoS One

A monoclonal antibody (1D12) defines novel distribution patterns of prion protein (PrP) as granules in nucleus

(2007) Tomoko Hosokawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS