The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1
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Title
The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1
Authors
Keywords
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Journal
NUCLEIC ACIDS RESEARCH
Volume 42, Issue 8, Pages 5217-5233
Publisher
Oxford University Press (OUP)
Online
2014-02-09
DOI
10.1093/nar/gku129
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- (2013) S. Jonas et al. GENES & DEVELOPMENT
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- Structural and functional control of the eukaryotic mRNA decapping machinery
- (2012) Marcos Arribas-Layton et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5′ exonucleolytic degradation
- (2012) Joerg E Braun et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC
- (2012) Marc R Fabian et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan
- (2012) S. N. Floor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Basis of the PNRC2-Mediated Link between mRNA Surveillance and Decapping
- (2012) Tingfeng Lai et al. STRUCTURE
- Identification and characterization of protein interactions in the mammalian mRNA processing body using a novel two-hybrid assay
- (2011) Donald B. Bloch et al. EXPERIMENTAL CELL RESEARCH
- Deciphering correct strategies for multiprotein complex assembly by co-expression: Application to complexes as large as the histone octamer
- (2011) Marie-Laure Diebold et al. JOURNAL OF STRUCTURAL BIOLOGY
- Attributes of short linear motifs
- (2011) Norman E. Davey et al. Molecular BioSystems
- Coupled 5′ Nucleotide Recognition and Processivity in Xrn1-Mediated mRNA Decay
- (2011) Martin Jinek et al. MOLECULAR CELL
- GW182 Proteins Directly Recruit Cytoplasmic Deadenylase Complexes to miRNA Targets
- (2011) Joerg E. Braun et al. MOLECULAR CELL
- Structural and biochemical studies of the 5′→3′ exoribonuclease Xrn1
- (2011) Jeong Ho Chang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A split active site couples cap recognition by Dcp2 to activation
- (2010) Stephen N Floor et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural and functional insights into eukaryotic mRNA decapping
- (2010) Sharon H. M. Ling et al. Wiley Interdisciplinary Reviews-RNA
- Protein structure prediction on the Web: a case study using the Phyre server
- (2009) Lawrence A Kelley et al. Nature Protocols
- DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa
- (2009) F. Tritschler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mRNA Decapping Is Promoted by an RNA-Binding Channel in Dcp2
- (2008) Mandar V. Deshmukh et al. MOLECULAR CELL
- Structural Basis of Dcp2 Recognition and Activation by Dcp1
- (2008) Meipei She et al. MOLECULAR CELL
- The C-terminal region of Ge-1 presents conserved structural features required for P-body localization
- (2008) M. Jinek et al. RNA
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