The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding

Human RecQ Helicases in DNA Repair, Recombination, and Replication

(2014) Deborah L. Croteau et al.   Annual Review of Biochemistry

Existence and consequences of G-quadruplex structures in DNA

(2014) Pierre Murat et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

CDK phosphorylation of SLD-2 is required for replication initiation and germline development inC. elegans

(2014) Vincent Gaggioli et al.   JOURNAL OF CELL BIOLOGY

Hrq1, a Homolog of the Human RecQ4 Helicase, Acts Catalytically and Structurally to Promote Genome Integrity

(2014) Matthew L. Bochman et al.   Cell Reports

Bioinformatic analysis of RecQ4 helicases reveals the presence of a RQC domain and a Zn knuckle

(2013) Francesca Marino et al.   BIOPHYSICAL CHEMISTRY

RECQL4 and p53 potentiate the activity of polymerase γ and maintain the integrity of the human mitochondrial genome

(2013) Shruti Gupta et al.   CARCINOGENESIS

The RECQL4 protein, deficient in Rothmund–Thomson syndrome is active on telomeric D-loops containing DNA metabolism blocking lesions

(2013) Leslie K. Ferrarelli et al.   DNA REPAIR

Neisseria gonorrhoeae RecQ Helicase HRDC Domains Are Essential for Efficient Binding and Unwinding of the pilE Guanine Quartet Structure Required for Pilin Antigenic Variation

(2013) L. A. Cahoon et al.   JOURNAL OF BACTERIOLOGY

The Replication Initiation Protein Sld2 Regulates Helicase Assembly

(2013) Irina Bruck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Origin Recognition Complex Binds Preferentially to G-quadruplex-preferable RNA and Single-stranded DNA

(2013) Shoko Hoshina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hrq1 functions independently of Sgs1 to preserve genome integrity in Saccharomyces cerevisiae

(2013) Do-Hee Choi et al.   JOURNAL OF MICROBIOLOGY

Genomes and G-Quadruplexes: For Better or for Worse

(2013) Madalena Tarsounas et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Scalable web services for the PSIPRED Protein Analysis Workbench

(2013) Daniel W. A. Buchan et al.   NUCLEIC ACIDS RESEARCH

DNA Replication Origins

(2013) A. C. Leonard et al.   Cold Spring Harbor Perspectives in Biology

RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity

(2012) Deborah L. Croteau et al.   AGING CELL

RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures

(2012) Venkateswarlu Popuri et al.   CELL CYCLE

New insights into replication origin characteristics in metazoans

(2012) Christelle Cayrou et al.   CELL CYCLE

RecQL4 cytoplasmic localization: Implications in mitochondrial DNA oxidative damage repair

(2012) Zhenfen Chi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress

(2012) S. De et al.   JOURNAL OF CELL SCIENCE

Unraveling cell type–specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs

(2012) Emilie Besnard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif

(2012) Oliver Ohlenschläger et al.   NUCLEIC ACIDS RESEARCH

The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability

(2012) Dharmendra Kumar Singh et al.   NUCLEIC ACIDS RESEARCH

RECQL4 in genomic instability and aging

(2012) Deborah L. Croteau et al.   TRENDS IN GENETICS

The N-terminal region of RECQL4 lacking the helicase domain is both essential and sufficient for the viability of vertebrate cells

(2011) Takuya Abe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The evolving world of protein-G-quadruplex recognition: A medicinal chemist’s perspective

(2011) Claudia Sissi et al.   BIOCHIMIE

Enabling Association of the GINS Protein Tetramer with the Mini Chromosome Maintenance (Mcm)2–7 Protein Complex by Phosphorylated Sld2 Protein and Single-stranded Origin DNA

(2011) Irina Bruck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RECQL4, the Protein Mutated in Rothmund-Thomson Syndrome, Functions in Telomere Maintenance

(2011) Avik K. Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RecQ4 Orthologue Hrq1 Is Critical for DNA Interstrand Cross-Link Repair and Genome Stability in Fission Yeast

(2011) L. M. Groocock et al.   MOLECULAR AND CELLULAR BIOLOGY

Cyclin-dependent kinase-dependent initiation of chromosomal DNA replication

(2010) Hiroyuki Araki   CURRENT OPINION IN CELL BIOLOGY

Rothmund–Thomson syndrome helicase, RECQ4: On the crossroad between DNA replication and repair

(2010) Yilun Liu   DNA REPAIR

Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding

(2010) Marie L. Rossi et al.   DNA REPAIR

Human RECQ1 and RECQ4 Helicases Play Distinct Roles in DNA Replication Initiation

(2010) S. Thangavel et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS Proteins

(2010) Ivar Ilves et al.   MOLECULAR CELL

Sld2 binds to origin single-stranded DNA and stimulates DNA annealing

(2010) Diane M. Kanter et al.   NUCLEIC ACIDS RESEARCH

G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae

(2010) John A. Capra et al.   PLoS Computational Biology

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

(2009) Xiaohua Xu et al.   EMBO JOURNAL

Dual DNA unwinding activities of the Rothmund–Thomson syndrome protein, RECQ4

(2009) Xiaohua Xu et al.   EMBO JOURNAL

DNA Helicase Activity in Purified Human RECQL4 Protein

(2009) Takahiro Suzuki et al.   JOURNAL OF BIOCHEMISTRY

DrosophilaRecQ4 Has a 3′-5′ DNA Helicase Activity That Is Essential for Viability

(2009) Christopher Capp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins

(2009) J.-S. Im et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modularity of intrinsic disorder in the human proteome

(2009) Melissa M. Pentony et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

RecQ helicases: guardian angels of the DNA replication fork

(2008) Csanád Z. Bachrati et al.   CHROMOSOMA

In silico analyses of a new group of fungal and plant RecQ4-homologous proteins

(2008) Fernanda Barea et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Drosophila homologue of the Rothmund–Thomson syndrome gene: Essential function in DNA replication during development

(2008) Jianhong Wu et al.   DEVELOPMENTAL BIOLOGY

The mutation spectrum in RECQL4 diseases

(2008) H Annika Siitonen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS