Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors

TLR7 Is Involved in Sequence-Specific Sensing of Single-Stranded RNAs in Human Macrophages

(2014) M. P. Gantier et al.   JOURNAL OF IMMUNOLOGY

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

The not-so-neutral role of microRNAs in neutrophil biology

(2013) Michael P. Gantier   JOURNAL OF LEUKOCYTE BIOLOGY

Inosine-Mediated Modulation of RNA Sensing by Toll-Like Receptor 7 (TLR7) and TLR8

(2013) S. T. Sarvestani et al.   JOURNAL OF VIROLOGY

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hepatotoxic Potential of Therapeutic Oligonucleotides Can Be Predicted from Their Sequence and Modification Pattern

(2013) Peter H. Hagedorn et al.   Nucleic Acid Therapeutics

Improved Performance of Anti-miRNA Oligonucleotides Using a Novel Non-Nucleotide Modifier

(2013) Kim A Lennox et al.   Molecular Therapy-Nucleic Acids

The 2′-O-methylation status of a single guanosine controls transfer RNA–mediated Toll-like receptor 7 activation or inhibition

(2012) Stefanie Jöckel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Toll-Like Receptor 8 Can Be Cool Too: Implications for Foreign RNA Sensing

(2012) Soroush T. Sarvestani et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

A miR-19 regulon that controls NF-κB signaling

(2012) Michael P. Gantier et al.   NUCLEIC ACIDS RESEARCH

The Business of RNAi Therapeutics in 2012

(2012) Dirk Haussecker   Molecular Therapy-Nucleic Acids

FIMO: scanning for occurrences of a given motif

(2011) Charles E. Grant et al.   BIOINFORMATICS

Chemical modification and design of anti-miRNA oligonucleotides

(2011) K A Lennox et al.   GENE THERAPY

Innate Immune Sensing of Retroviral Infection via Toll-like Receptor 7 Occurs upon Viral Entry

(2011) Melissa Kane et al.   IMMUNITY

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

(2011) Roland Züst et al.   NATURE IMMUNOLOGY

Genetic modulation of TLR8 response following bacterial phagocytosis

(2010) Michael P. Gantier et al.   HUMAN MUTATION

Rational Design of Immunostimulatory siRNAs

(2010) Michael P Gantier et al.   MOLECULAR THERAPY

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

A Direct Comparison of Anti-microRNA Oligonucleotide Potency

(2010) Kim A. Lennox et al.   PHARMACEUTICAL RESEARCH

The DIANA-mirExTra Web Server: From Gene Expression Data to MicroRNA Function

(2010) Panagiotis Alexiou et al.   PLoS One

Alternating 2′-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist

(2009) Svetlana Hamm et al.   IMMUNOBIOLOGY

Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses

(2009) S. Tluk et al.   INTERNATIONAL IMMUNOLOGY

Toll-like receptor-mediated activation of neutrophils by influenza A virus

(2008) J. P. Wang et al.   BLOOD

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

Getting to the Root of miRNA-Mediated Gene Silencing

(2008) Ana Eulalio et al.   CELL

Determinants of Cytokine Induction by Small Interfering RNA in Human Peripheral Blood Mononuclear Cells

(2008) Maryam Zamanian-Daryoush et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE