Evolution at protein ends: major contribution of alternative transcription initiation and termination to the transcriptome and proteome diversity in mammals

Landscape and variation of RNA secondary structure across the human transcriptome

(2014) Yue Wan et al.   NATURE

Promiscuity as a functional trait: intrinsically disordered regions as central players of interactomes

(2013) Alexander Cumberworth et al.   BIOCHEMICAL JOURNAL

Dynamic Integration of Splicing within Gene Regulatory Pathways

(2013) Ulrich Braunschweig et al.   CELL

The impact of splicing on protein domain architecture

(2013) Sara Light et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Alternative splicing of intrinsically disordered regions and rewiring of protein interactions

(2013) Marija Buljan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Transcriptome and genome sequencing uncovers functional variation in humans

(2013) Tuuli Lappalainen et al.   NATURE

Alternative splicing: a pivotal step between eukaryotic transcription and translation

(2013) Alberto R. Kornblihtt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sounds of silence: synonymous nucleotides as a key to biological regulation and complexity

(2013) S. A. Shabalina et al.   NUCLEIC ACIDS RESEARCH

Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution

(2013) A. B. Stergachis et al.   SCIENCE

Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins

(2012) Eric T. Wang et al.   CELL

Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs

(2012) H. Tilgner et al.   GENOME RESEARCH

A quantitative atlas of polyadenylation in five mammals

(2012) Adnan Derti et al.   GENOME RESEARCH

Tissue-Specific Alternative Splicing Remodels Protein-Protein Interaction Networks

(2012) Jonathan D. Ellis et al.   MOLECULAR CELL

Tissue-Specific Splicing of Disordered Segments that Embed Binding Motifs Rewires Protein Interaction Networks

(2012) Marija Buljan et al.   MOLECULAR CELL

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Linear motifs confer functional diversity onto splice variants

(2012) Robert J. Weatheritt et al.   NUCLEIC ACIDS RESEARCH

Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues

(2012) J. Merkin et al.   SCIENCE

The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

(2012) N. L. Barbosa-Morais et al.   SCIENCE

Alternative Splicing of RNA Triplets Is Often Regulated and Accelerates Proteome Evolution

(2012) Robert K. Bradley et al.   PLOS BIOLOGY

Genome-wide functional analysis of human 5' untranslated region introns

(2012) Can Cenik et al.   GENOME BIOLOGY

Disruptive mRNA folding increases translational efficiency of catechol-O-methyltransferase variant

(2011) Douglas Tsao et al.   NUCLEIC ACIDS RESEARCH

An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

(2011) Irina M. Shapiro et al.   PLoS Genetics

Connections between Alternative Transcription and Alternative Splicing in Mammals

(2010) Svetlana A. Shabalina et al.   Genome Biology and Evolution

CDD: a Conserved Domain Database for the functional annotation of proteins

(2010) A. Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Tissue-Specific and Ubiquitous Expression Patterns from Alternative Promoters of Human Genes

(2010) Edwin Jacox et al.   PLoS One

Differential Arginylation of Actin Isoforms Is Regulated by Coding Sequence-Dependent Degradation

(2010) F. Zhang et al.   SCIENCE

Evolution of alternative and constitutive regions of mammalian 5'UTRs

(2009) Alissa M Resch et al.   BMC GENOMICS

Systematic analysis of alternative promoters correlated with alternative splicing in human genes

(2009) Xiaojuan Ma et al.   GENOMICS

UTRdb and UTRsite (RELEASE 2010): a collection of sequences and regulatory motifs of the untranslated regions of eukaryotic mRNAs

(2009) Giorgio Grillo et al.   NUCLEIC ACIDS RESEARCH

DBTSS provides a tissue specific dynamic view of Transcription Start Sites

(2009) Riu Yamashita et al.   NUCLEIC ACIDS RESEARCH

Predicting Functional Alternative Splicing by Measuring RNA Selection Pressure from Multigenome Alignments

(2009) Hongchao Lu et al.   PLoS Computational Biology

Expansion of the human μ-opioid receptor gene architecture: novel functional variants

(2008) Svetlana A. Shabalina et al.   HUMAN MOLECULAR GENETICS

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution

(2008) Brian T. Wilhelm et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

Alternative Promoters Influence Alternative Splicing at the Genomic Level

(2008) Dedong Xin et al.   PLoS One

Expression Patterns of Protein Kinases Correlate with Gene Architecture and Evolutionary Rates

(2008) Aleksey Y. Ogurtsov et al.   PLoS One

A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome

(2008) M. Sultan et al.   SCIENCE

Alternative splicing: current perspectives

(2007) Eddo Kim et al.   BIOESSAYS