Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays

Optimization of Potent Hepatitis C Virus NS3 Helicase Inhibitors Isolated from the Yellow Dyes Thioflavine S and Primuline

(2012) Kelin Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Small Molecule Inhibition of RISC Loading

(2011) Grace S. Tan et al.   ACS Chemical Biology

Mutations in HCV non-structural genes do not contribute to resistance to nitazoxanide in replicon-containing cells

(2011) Changsuek Yon et al.   ANTIVIRAL RESEARCH

Inhibition of the helicase activity of the HCV NS3 protein by symmetrical dimeric bis-benzimidazoles

(2011) Vera L. Tunitskaya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Effect of ASP2151, a Herpesvirus Helicase-Primase Inhibitor, in a Guinea Pig Model of Genital Herpes

(2011) Kiyomitsu Katsumata et al.   MOLECULES

PubChem's BioAssay Database

(2011) Y. Wang et al.   NUCLEIC ACIDS RESEARCH

A macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target

(2011) N. Schiering et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism and Specificity of a Symmetrical Benzimidazolephenylcarboxamide Helicase Inhibitor

(2010) Craig A. Belon et al.   BIOCHEMISTRY

Studies on the anti-hepatitis C virus activity of newly synthesized tropolone derivatives: Identification of NS3 helicase inhibitors that specifically inhibit subgenomic HCV replication

(2010) Andżelika Najda-Bernatowicz et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of potent nucleotide-mimicking competitive inhibitors of hepatitis C virus NS3 helicase

(2010) Sandra Gemma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of New Acridone Derivatives, Inhibitors of NS3 Helicase, Which Efficiently and Specifically Inhibit Subgenomic HCV Replication

(2010) Anna Stankiewicz-Drogoń et al.   JOURNAL OF MEDICINAL CHEMISTRY

Visualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCV

(2010) Todd C. Appleby et al.   JOURNAL OF MOLECULAR BIOLOGY

Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity

(2010) Dorjbal Dorjsuren et al.   NUCLEIC ACIDS RESEARCH

Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism

(2010) M. Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of specific inhibitors for a trypanosomatid RNA editing reaction

(2010) S. Liang et al.   RNA

Quantitative approaches to monitor protein-nucleic acid interactions using fluorescent probes

(2010) J. M. Pagano et al.   RNA

Amidinoanthracyclines – a new group of potential anti-hepatitis C virus compounds

(2009) Mariusz Krawczyk et al.   BIOLOGICAL CHEMISTRY

Helicase inhibitors as specifically targeted antiviral therapy for hepatitis C

(2009) Craig A Belon et al.   Future Virology

Inhibition of Subgenomic Hepatitis C Virus RNA Replication by Acridone Derivatives: Identification of an NS3 Helicase Inhibitor

(2009) Giuseppe Manfroni et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure-Based Discovery of Triphenylmethane Derivatives as Inhibitors of Hepatitis C Virus Helicase∞

(2009) Chien-Shu Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fuel Specificity of the Hepatitis C Virus NS3 Helicase

(2009) Craig A. Belon et al.   JOURNAL OF MOLECULAR BIOLOGY

Aurintricarboxylic Acid Is a Potent Inhibitor of Influenza A and B Virus Neuraminidases

(2009) Anwar M. Hashem et al.   PLoS One

Monitoring helicase activity with molecular beacons

(2008) Craig A. Belon et al.   BIOTECHNIQUES