Quadruplex-single nucleotide polymorphisms (Quad-SNP) influence gene expression difference among individuals

Heterogeneous Nuclear Ribonucleoprotein K and Nucleolin as Transcriptional Activators of the Vascular Endothelial Growth Factor Promoter through Interaction with Secondary DNA Structures

(2011) Diana J. Uribe et al.   BIOCHEMISTRY

Formation of (3+1) G-Quadruplexes with a Long Loop by Human Telomeric DNA Spanning Five or More Repeats

(2011) Doris Jia En Yue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

Zinc-finger transcription factors are associated with guanine quadruplex motifs in human, chimpanzee, mouse and rat promoters genome-wide

(2011) Pankaj Kumar et al.   NUCLEIC ACIDS RESEARCH

Rare and Common Regulatory Variation in Population-Scale Sequenced Human Genomes

(2011) Stephen B. Montgomery et al.   PLoS Genetics

A novel G-quadruplex motif modulates promoter activity of human thymidine kinase 1

(2010) Richa Basundra et al.   FEBS Journal

Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes

(2010) D. L. Goode et al.   GENOME RESEARCH

TheKRASPromoter Responds to Myc-associated Zinc Finger and Poly(ADP-ribose) Polymerase 1 Proteins, Which Recognize a Critical Quadruplex-formingGA-element

(2010) Susanna Cogoi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coexistence of Two Distinct G-Quadruplex Conformations in the hTERT Promoter

(2010) Kah Wai Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Guanine quadruplex DNA structure restricts methylation of CpG dinucleotides genome-wide

(2010) Rashi Halder et al.   Molecular BioSystems

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Single-nucleotide evolutionary constraint scores highlight disease-causing mutations

(2010) Gregory M Cooper et al.   NATURE METHODS

Quadruplex structures of muscle gene promoter sequences enhance in vivo MyoD-dependent gene expression

(2010) Jeny Shklover et al.   NUCLEIC ACIDS RESEARCH

How long is too long? Effects of loop size on G-quadruplex stability

(2010) Aurore Guédin et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Profiling of p63 DNA–Binding Sites Identifies an Element that Regulates Gene Expression during Limb Development in the 7q21 SHFM1 Locus

(2010) Evelyn N. Kouwenhoven et al.   PLoS Genetics

Non-B DNA structure-induced genetic instability and evolution

(2009) Junhua Zhao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Formation of a Unique End-to-End Stacked Pair of G-Quadruplexes in the hTERT Core Promoter with Implications for Inhibition of Telomerase by G-Quadruplex-Interactive Ligands

(2009) SunMi L. Palumbo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stable G-quadruplexes are found outside nucleosome-bound regions

(2009) Han Min Wong et al.   Molecular BioSystems

Genome-wide analysis predicts DNA structural motifs as nucleosome exclusion signals

(2009) Kangkan Halder et al.   Molecular BioSystems

The disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterparts

(2009) S. Nakken et al.   NUCLEIC ACIDS RESEARCH

Protein hnRNP A1 and its derivative Up1 unfold quadruplex DNA in the human KRAS promoter: implications for transcription

(2009) Manikandan Paramasivam et al.   NUCLEIC ACIDS RESEARCH

Evidence of genome-wide G4 DNA-mediated gene expression in human cancer cells

(2009) Anjali Verma et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Analyses of Recombination Prone Regions Predict Role of DNA Structural Motif in Recombination

(2009) Prithvi Mani et al.   PLoS One

Genome-Wide Computational and Expression Analyses Reveal G-Quadruplex DNA Motifs as Conservedcis-Regulatory Elements in Human and Related Species

(2008) Anjali Verma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Natural selection has driven population differentiation in modern humans

(2008) Luis B Barreiro et al.   NATURE GENETICS

Differential binding of quadruplex structures of muscle-specific genes regulatory sequences by MyoD, MRF4 and myogenin

(2008) A. Yafe et al.   NUCLEIC ACIDS RESEARCH

Metastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expression

(2008) Ram Krishna Thakur et al.   NUCLEIC ACIDS RESEARCH