Review
Chemistry, Multidisciplinary
Florian Junge, Pin-Wei Lee, Abhishek Kumar Singh, Janos Wasternack, Michal P. Pachnicz, Rainer Haag, Christoph A. A. Schalley
Summary: This Minireview discusses recent developments in research on the interfacial phenomena of fluorinated amphiphiles, with a focus on applications that exploit the unique and manifold interfacial properties associated with these amphiphiles. Specifically, the article highlights the formation of stable aggregates with different morphologies compared to nonfluorinated counterparts, the use of fluorinated surfactants in high-performance applications such as microfluidic-assisted screening, and the fluorine-specific behavior at solid/liquid interfaces, including the formation of superhydrophobic coatings. It also evaluates recent developments in the remediation of fluorinated surfactants and perfluorinated materials based on their adsorption onto fluorinated surfaces.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Chemistry, Physical
Syed Muhammad Shakil Hussain, Ahmad A. Adewunmi, Ahmad Mahboob, Mobeen Murtaza, Xianmin Zhou, Muhammad Shahzad Kamal
Summary: The selection of appropriate chemicals and the synthetic method is crucial for oilfield applications. Fluorinated surfactants, with their distinct properties, have various applications, but environmental concerns limit their usage.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Physical
T. Shalini, R. Ajay Rakkesh, P. Bargavi, S. Balakumar
Summary: In this study, innovative and economic protocols were used to fabricate monetite calcium phosphate with differently charged surfactants. The morphology, size, and surface charge of the surfactant-assisted monetite were significantly different from pristine monetite. The biocompatibility of the surfactant-assisted monetite particles was assessed through in-vitro protein adsorption studies, revealing dominant live cells in the surfactant-assisted monetite.
SURFACES AND INTERFACES
(2023)
Article
Biochemistry & Molecular Biology
Jack Porter, Daniele Parisi, Timothy Miller, Aisling Ni Cheallaigh, Gavin J. Miller
Summary: Amphiphilic glycoconjugates have great potential as chemical biology tools and biosurfactants. To expedite their development, chemical synthesis is necessary, especially for oleyl glycosides. In this study, a mild and reliable glycosylation method was developed to access oleyl glucosides, allowing for the synthesis of novel fluorinated and sulfhydryl-modified glucosides and glucosamines of oleyl alcohol. These compounds provide valuable tools for investigating oleyl glycosides in various processes and materials, including glycosphingolipid metabolism.
CARBOHYDRATE RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Zexian Xu, Yali Li, Dian Xu, Li Li, Yaoxiang Xu, Liqiang Chen, Yanshan Liu, Jian Sun
Summary: Nano-hydroxyapatite (nHA) is enhanced with fluorinated graphene oxide (FG) to improve its formability, mechanical properties, antimicrobial activity, and clinical application. The nHA/FG composite scaffold shows improved mechanical properties, with a uniform distribution of FG. The composite scaffold exhibits satisfactory cytocompatibility and antibacterial properties.
Article
Nanoscience & Nanotechnology
Jiahe Liu, Xiaoyan Lyu, Ziwei Zhou, Lin Yang, Jie Zeng, Yao Yang, Zhenghuan Zhao, Rui Chen, Xin Tong, Jiaqi Li, Hailan Liu, Yuan Zou
Summary: The ability to encapsulate and manipulate droplets with a picoliter volume of samples and reagents shows great potential for practical applications in chemistry, biology, and materials science. Magnetic control is a promising approach for droplet manipulation due to its ability for wireless control and its ease of implementation. However, it is challenged by the poor biocompatibility of magnetic materials in aqueous droplets, and current droplet technology is problematic because of molecule leakage between droplets.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Materials Science, Multidisciplinary
Shanmugasundaram Kumaraguru, Ravi Nivetha, Kasi Gopinath, Elumalai Sundaravadivel, Bader O. Almutairi, Mikhlid H. Almutairi, Shahid Mahboob, M. R. Kavipriya, Marcello Nicoletti, Marimuthu Govindarajan
Summary: New composites of cerium oxide were successfully incorporated in the copper-based metal organic framework using the precipitation method. The Cu-MOF/CeO2 nanocomposite exhibited excellent electrocatalytic performance towards hydrogen evolution reaction and displayed high biocompatibility for targeted drug delivery applications.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Review
Chemistry, Physical
Suman Chowdhury, Atanu Rakshit, Animesh Acharjee, Bidyut Saha
Summary: The importance of surfactants in flexible usability has increased significantly, leading to a focus on the synthesis of green surfactants to maintain product sustainability.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Applied
Feng Wang, Yinghua Gao, Jiahui Zhang, Laixing Wang, Leilei Bao, Yan Qiu, Hui Jin, Yijia Yan, Yiping Han, Feng Hong, Zhi-Long Chen
Summary: A series of chlorophyll derivatives with fluorine-substituted alkyl side chains were designed and synthesized, showing excellent photodynamic anti-tumor effects. Among them, compound F-C4-Ppa exhibited the most outstanding anti-tumor effect and is a promising candidate for photodynamic therapy and photo-imaging diagnosis.
Article
Chemistry, Medicinal
Jakob Bouton, Arno Furquim d'Almeida, Louis Maes, Guy Caljon, Serge Van Calenbergh, Fabian Hulpia
Summary: Kinetoplastid parasites rely on purine salvage for their purine demand. Evaluating the effect of introducing a 3'-fluoro substituent in 7-deazapurine nucleosides, several analogs with potent anti-parasitic activity were discovered, showing that a fluorine atom in the 3'-position is a promising modification for the discovery of anti-parasitic nucleosides.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Man-Yi Li, Ying-Hua Gao, Jia -Hui Zhang, Le Mi, Xue-Xue Zhu, Feng Wang, Xing-Ping Zhou, Yi-Jia Yan, Zhi-Long Chen
Summary: A series of novel fluorinated hematoporphyrin ether derivatives were successfully synthesized in this study, among which one compound, II3, showed high phototoxicity, strong effectiveness against lung cancer cells, and promising anti-tumor effects in vivo, making it a potential new drug candidate for photodynamic therapy.
BIOORGANIC CHEMISTRY
(2021)
Article
Chemistry, Medicinal
Michele Verboni, Diego Romano Perinelli, Carol Yingshan Qiu, Mattia Tiboni, Annalisa Aluigi, Simone Lucarini, Jenny K. W. Lam, Andrea Duranti
Summary: Sugar-based ester surfactants, including sucrose and lactose derivatives, were synthesized and tested for their physicochemical properties, structure-property relationship, cytotoxicity, and permeability-enhancing activity on Calu-3 cells. The results showed that the surfactants had no significant cytotoxic effect and could significantly enhance the permeability of FTIC-dextran across the cells. These findings indicate that these sugar-based ester surfactants have the potential to be safe and effective permeation enhancers for pharmaceutical applications.
Article
Pharmacology & Pharmacy
Sabrina Sciabica, Giovanni Tafuro, Alessandra Semenzato, Daniela Traini, Dina M. Silva, Larissa Gomes Dos Reis, Luisa Canilli, Massimo Terno, Elisa Durini, Silvia Vertuani, Anna Baldisserotto, Stefano Manfredini
Summary: By modifying native HA through cross-linking reactions with Ornithine, the half-life and performance of the new product (HA-Orn) were improved. The gel-like profile of HA-Orn showed improved resistance against enzymatic digestion, and in vitro cytotoxicity studies demonstrated no cytotoxicity on lung cell lines.
Article
Chemistry, Multidisciplinary
Moheddine Wehbie, Kenechi Kanayo Onyia, Florian Mahler, Aline Le Roy, Anais Deletraz, Ilham Bouchemal, Carolyn Vargas, Jonathan Oyebamiji Babalola, Cecile Breyton, Christine Ebel, Sandro Keller, Gregory Durand
Summary: Two new partially fluorinated surfactants, F5OM and F5DM, were designed as analogues of n-dodecyl-beta-D-maltoside (DDM) and showed promising properties in solubilizing lipid vesicles and extracting membrane proteins. Their micellization properties and morphologies were evaluated, indicating potential applications in membrane protein research.
Article
Chemistry, Multidisciplinary
Alexander Rittner, Mirko Joppe, Jennifer J. Schmidt, Lara Maria Mayer, Simon Reiners, Elia Heid, Dietmar Herzberg, David H. Sherman, Martin Grininger
Summary: This study reports a strategy to introduce fluorine into complex polyketides during biosynthesis. By exchanging a domain of the polyketide synthase, the ability to incorporate fluorine during polyketide chain extension was achieved. The results demonstrate the potential application of this method in the chemoenzymatic synthesis of fluorinated compounds.
Article
Engineering, Environmental
Riley M. Behan-Bush, Jesse N. Liszewski, Michael V. Schrodt, Bhavya Vats, Xueshu Li, Hans-Joachim Lehmler, Aloysius J. Klingelhutz, James A. Ankrum
Summary: This study investigates the effects of PCB mixtures found in U.S. schools on the health and function of human adipose MSCs. The results show that exposure to these mixtures leads to cell death and phenotypic changes in MSCs. Additionally, exposure to these mixtures leads to impaired adipogenesis and decreased immunosuppressive capabilities of MSCs. Therefore, PCB mixtures found in schools have a negative impact on the health and function of adipose MSCs.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Medicinal
Neha Paranjape, Laura E. Dean, Andres Martinez, Ronald B. Tjalkens, Hans-Joachim Lehmler, Jonathan A. Doorn
Summary: This study reveals the important role of astrocytes in PCB-mediated neurotoxicity, highlighting the toxicity of PCB52 and its metabolites in these glial cells. The findings emphasize the need for further research on the mechanisms of PCB exposure in astrocytes.
CHEMICAL RESEARCH IN TOXICOLOGY
(2023)
Article
Environmental Sciences
Darrin A. Thompson, Dana W. Kolpin, Michelle L. Hladik, Hans -Joachim Lehmler, Shannon M. Meppelink, Matthew C. Poch, John D. Vargo, Victor A. Soupene, Nafis Md Irfan, Morgan Robinson, Kurunthachalam Kannan, Laura E. Beane Freeman, Jonathan N. Hofmann, David M. Cwiertny, R. William Field
Summary: A pilot study was conducted in eastern Iowa to assess human exposure to neon-icotinoids (NEOs) among farming households. The study found that NEOs were detected in both outdoor and indoor water samples, with clothianidin being the most frequently detected NEO. Human exposure to NEOs was also found in urine samples, with multiple NEOs and metabolites being present. Additionally, the study concluded that while water consumption may contribute to exposure, other factors like diet and occupational exposure may play a bigger role.
Article
Environmental Sciences
Julia S. Mouat, Xueshu Li, Kari Neier, Yihui Zhu, Charles E. Mordaunt, Michele A. La Merrill, Hans -Joachim Lehmler, Michael P. Jones, Pamela J. Lein, Rebecca J. Schmidt, Janine M. LaSalle
Summary: This study aimed to explore the impact of gestational exposure to polychlorinated biphenyls (PCBs) on placental epigenetics and its correlation with child neurodevelopmental outcomes. The results suggested that placental DNA co-methylation modules were associated with maternal PCB levels and child neurodevelopment, particularly the methylation of CSMD1 and AUTS2, which could be potential markers of altered placental function and/or increased risk of autism spectrum disorder (ASD) following maternal PCB exposure.
ENVIRONMENTAL RESEARCH
(2023)
Letter
Engineering, Environmental
Chun-Yun Zhang, Xueshu Li, Kimberly P. Keil Stietz, Sunjay Sethi, Weizhu Yang, Rachel F. Marek, Xinxin Ding, Pamela J. Lein, Keri C. Hornbuckle, Hans-Joachim Lehmler
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Toxicology
Valerie A. Wagner, Katie L. Holl, Karen C. Clark, John J. Reho, Melinda R. Dwinell, Hans-Joachim Lehmler, Hershel Raff, Justin L. Grobe, Anne E. Kwitek
Summary: This study found that environmental bisphenol compounds such as bisphenol F (BPF) are endocrine-disrupting chemicals (EDCs) that affect adipose and classical endocrine systems. It was hypothesized that the founder strains of the HS rat exhibit EDC effects that are strain- and sex-dependent. The results showed that BPF exposure leads to specific post-exposure effects in rats of different strains and sexes, revealing the presence of diverse bisphenol-exposure risk alleles in the HS rat founder population.
TOXICOLOGICAL SCIENCES
(2023)
Article
Environmental Sciences
Hunter W. Schroer, Esteban Londono, Xueshu Li, Hans-Joachim Lehmler, William Arnold, Craig L. Just
Summary: Insensitive munitions formulations containing NTO are replacing traditional explosive compounds, but the widespread use of NTO raises concerns about environmental contamination and cleanup. This study examines the mechanisms and products of NTO photolysis in sunlit surface waters, demonstrating the production of singlet oxygen and the influence of dissolved oxygen and pH on the photolysis rate. The major reaction products are ammonium, nitrite, and nitrate.
Article
Chemistry, Medicinal
Xueshu Li, Amanda J. Bullert, Weiguo Han, Weizhu Yang, Qing-Yu Zhang, Xinxin Ding, Hans-Joachim Lehmler
Summary: This study investigates the metabolism of PCB 95 in transgenic mouse models and its impact on neurotoxicity. The results demonstrate differences in PCB 95 levels and metabolite profiles among different tissues, as well as minor variations based on sex and genotype. These findings highlight the importance of transgenic mouse models in understanding the relationship between PCB metabolism and neurotoxicity.
CHEMICAL RESEARCH IN TOXICOLOGY
(2023)
Article
Engineering, Environmental
Riley M. Behan-Bush, Jesse N. Liszewski, Michael V. Schrodt, Bhavya Vats, Xueshu Li, Hans-Joachim Lehmler, Aloysius J. Klingelhutz, James A. Ankrum
Summary: This study found that exposure to PCB mixtures in schools negatively affects the growth and function of adipose mesenchymal stem/stromal cells (MSCs). Different levels of toxicity were observed when MSCs were exposed to Aroclor 1016, Aroclor 1254, and Cabinet Mixture. The findings have important implications for human health, considering the role of MSCs in supporting and maintaining adipose tissue.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Endocrinology & Metabolism
Valerie A. Wagner, Katie L. Holl, Karen C. Clark, John J. Reho, Hans-Joachim Lehmler, Kai Wang, Justin L. Grobe, Melinda R. Dwinell, Hershel Raff, Anne E. Kwitek
Summary: This study reveals the diversity of endocrine health conditions in N/NIH HS rats due to genetic diversity, and the potential of these rats in investigating cardiovascular metabolic disease risks.
Article
Chemistry, Multidisciplinary
Zihan Ma, Lishuang Wang, Tingting Chen, Guangning Wang
Summary: In this study, two kinds of 3D self-doped (N/O) lilac-based and coriander-based porous carbons with high performance have been prepared.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Qin Wang, Yun-Fan Yan, Jiao-Lin Weng, Ying Huang, Fu Yang, Hao-Hui Xie, Fei Tan, Fa-Kun Zheng, Jian-Gang Xu
Summary: Balancing energy and mechanical sensitivities is a challenging issue in the field of energetic materials. This study constructed a 3D energetic metal-organic framework with nitrogen-rich ligand and NO3- anions. The framework demonstrated high stability, energy density, and excellent mechanical sensitivities, making it a potential insensitive energetic material.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Marrium Saeed, Urooj Kamran, Amina Khan, Md Irfanul Haque Siddiqui, Hasan Jamal, Haq Nawaz Bhatti
Summary: In this study, magnesium-aluminum layered double hydroxides (Mg-Al-LDH) were synthesized using an environmentally friendly hydrothermal technique for adsorbing the dye reactive green 5 (RG5). To improve the adsorption capability, composites were prepared by combining Mg-Al-LDH with low-cost Mangifera indica stone biomass (MISB). The results showed that the composites had high adsorption capacities for RG5 dye and could be regenerated.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Xuanlin Zhan, Xiaojie Li, Yunyan Zeng, Siyan Jiang, Chao Pan, Shiyu Pan, Jiaquan Huang, Heqian Zhang, Zhiwei Qin
Summary: This study reports on the potential prospects of natural products derived from the rhizosphere for the development of antibiotics and herbicides, as well as the advancements in cultivating a mutant strain that produces a substantial quantity of lydicamycins, a potent family for herbicide development.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Jie Zhu, Jiangtao Yu, Linhua Zhu, Xiaoxiao Yu, Jixing Liu, Yanhong Chao, Jingzhou Yin, Peiwen Wu, Jian Liu, Wenshuai Zhu
Summary: This study successfully demonstrates the 3D printing of attapulgite monoliths and investigates the influence of thermal treatment on their properties. The thermal treated monoliths show superior catalytic performance at low temperatures.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yanzhu Ye, Yixiang Ye, Jiannan Cai, Zhongshui Li, Shen Lin
Summary: In this paper, a novel Pt/CoP/C photo-electro synergistic catalyst was successfully synthesized and its performance was investigated. The catalyst exhibited excellent photo-electro catalytic performance, with significantly higher hydrogen production compared to a commercial catalyst. The introduction of cobalt phosphide and the existence of Co3O4 were identified as key factors for enhancing the catalytic activity.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Nurul Hidayah Abu Bakar, Wan Norfazilah Wan Ismail, Hartina Mohd Yusop, Noreen Farzuhana Mohd Zulkifli
Summary: Hydrophobic coatings inspired by the lotus effect have gained popularity for their ability to solve various problems. The sol-gel method, utilizing silica, alumina, and titania, is explored as an environmentally friendly approach to produce water-based hydrophobic coatings. This study focuses on producing water-based hydrophobic coatings for cotton and polyester fabrics using a one-step sol-gel method. The coated fabrics exhibited improved hydrophobic properties, altered surface morphologies, and lower air permeability compared to uncoated fabrics. TEOS-PDMS coating provides a promising approach for enhancing the hydrophobic and surface properties of cotton and polyester fabrics.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Nikita Belko, Hanna Maltanava, Anatol Lugovski, Polina Shabunya, Sviatlana Fatykhava, Evgeny Bondarenko, Pavel Chulkin, Sergey Poznyak, Michael Samtsov
Summary: This study investigates the difference in electrochemical behavior between rhodamine B hydrazide and rhodamine B acylhydrazone, and finds that rhodamine B acylhydrazone exhibits higher reversibility in electrooxidation. These results can be applied for developing new sensors with desired electrochemical properties.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Showket Ahmad Bhat, Mohd Ikram
Summary: In this study, 0-3 particulate multiferroic composites were synthesized and characterized. The composites exhibited excellent ferroelectric and ferromagnetic properties, as well as high piezoelectric strain and magnetoelectric coupling effects.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Carla Gomes, Mariana Costa, Susana M. M. Lopes, Bernardo Albuquerque Nogueira, Rui Fausto, Jose A. Paixao, Teresa M. V. D. e Melo, Luisa M. D. R. S. Martins, Marta Pineiro
Summary: The development of sustainable processes requires the integration of green chemistry principles. In this study, a solvent-free synthesis method was developed to prepare new copper catalysts, which efficiently catalyze cycloaddition reactions under solvent-free mechanochemical conditions. Through this process, the principles of atom economy, reduction of solvents and auxiliaries, design for energy efficiency, and reduction of derivatives and catalysis are combined.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Zhihua Liu, Jinzhe Li, Jianguo Zhou
Summary: This study demonstrates the enhancement of photoelectrochemical activity of BiFeO3 photoelectrodes through ion modification, which increases visible light absorption and active area, leading to improved PEC water splitting performance.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yisheng Zhang, Wensong Li, Jing Li, Fang Li, Wei Xue, Xinqiang Zhao, Yanji Wang
Summary: Pt/C and SO42-/ZrO2 were used as catalysts for the synthesis of p-aminophenol through the catalytic transfer hydrogenation of nitrobenzene in water with formic acid as the hydrogen source. The optimal Pt loading for PAP selectivity was found to be 1 wt%. The presence of different valence states of Pt affected both the nitrobenzene hydrogenation and formic acid decomposition. Among different solid acid catalysts tested, SO42-/ZrO2 exhibited the highest catalytic activity for p-aminophenol formation. Under the optimized reaction conditions, the conversion of nitrobenzene reached 80.0%, with a selectivity of 47.6% for p-aminophenol.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Pradyota Kumar Behera, Papita Behera, Amlan Swain, Santosh Kumar Sahu, Ajeena Sahoo, Laxmidhar Rout
Summary: We have developed a simple and direct method for the synthesis of diaryl ether using an oxygen bridged bimetallic CuMoO4 nanocatalyst under mild reaction conditions. The catalyst exhibited tolerance towards a wide range of substrates with various functional groups. It is efficient and recyclable. This methodology allows easy access to nitrofen derivatives (herbicides) from unactivated 2,4-dichlorophenol, which are important for agriculture and pharmaceuticals.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Yihua Fu, Yan Zhang, Changwei Hu, Zhishan Su
Summary: The mechanism of the reaction between CO2 and styrene oxide for cyclic carbonate was revealed using density functional theory calculations. The noncatalytic reaction occurred via a concerted mechanism, while in the presence of guanidine and tetrabutylammonium iodide (TBAI) co-catalysts, the epoxide ring-opening by nucleophilic attack of an iodide anion was predicted to be the rate-determining step. Guanidine acted as the H-bond donor to activate styrene oxide, facilitating the reaction with a lower activation barrier.
NEW JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Saikat Khamarui, Sirshendu Ghosh
Summary: Copper nanorods (Cu-NRs) exhibit significant plasmonic behavior and can act as efficient catalysts in redox processes and coupling. A benign decarboxylative approach, utilizing localized surface plasmon resonance (LSPR) assisted catalysis with Cu-NRs, has been developed for the production of alkane analogues from alkyl carboxylic acids under visible light. The catalyst shows a broad substrate scope and high functional group tolerance, without the need for an external oxidant or proton source. A plausible mechanism for this recyclable nano-catalyst has also been proposed based on control experiments.
NEW JOURNAL OF CHEMISTRY
(2024)