Notch Receptor-Ligand Engagement Maintains Hematopoietic Stem Cell Quiescence and Niche Retention

Notch-Dependent Repression of miR-155 in the Bone Marrow Niche Regulates Hematopoiesis in an NF-κB-Dependent Manner

(2014) Lin Wang et al.   Cell Stem Cell

O-fucosylation of the Notch Ligand mDLL1 by POFUT1 Is Dispensable for Ligand Function

(2014) Julia Müller et al.   PLoS One

An Evolutionary-Conserved Function of Mammalian Notch Family Members as Cell Adhesion Molecules

(2014) Akihiko Murata et al.   PLoS One

Regional Localization within the Bone Marrow Influences the Functional Capacity of Human HSCs

(2013) Borhane Guezguez et al.   Cell Stem Cell

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

(2013) Adam Greenbaum et al.   NATURE

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

Arteriolar niches maintain haematopoietic stem cell quiescence

(2013) Yuya Kunisaki et al.   NATURE

Deltex-1 Activates Mitotic Signaling and Proliferation and Increases the Clonogenic and Invasive Potential of U373 and LN18 Glioblastoma Cells and Correlates with Patient Survival

(2013) Roland M. Huber et al.   PLoS One

Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated β1/β2-integrin trafficking

(2013) E. Taniguchi Ishikawa et al.   Nature Communications

Dynamic Imaging of Marrow-Resident Granulocytes Interacting with Human Mesenchymal Stem Cells upon Systemic Lipopolysaccharide Challenge

(2013) Jay T. Myers et al.   Stem Cells International

Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration

(2012) Dongsu Park et al.   Cell Stem Cell

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions

(2011) D. Yao et al.   BLOOD

Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis

(2011) M. Yoda et al.   BLOOD

Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells

(2011) Barbara Varnum-Finney et al.   JOURNAL OF CLINICAL INVESTIGATION

Bone marrow CD169+macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

(2011) Andrew Chow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

(2010) I. G. Winkler et al.   BLOOD

Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

(2010) Jason M. Butler et al.   Cell Stem Cell

A Notch Ligand, Delta-Like 1 Functions As an Adhesion Molecule for Mast Cells

(2010) A. Murata et al.   JOURNAL OF IMMUNOLOGY

Chronic DLL4 blockade induces vascular neoplasms

(2010) Minhong Yan et al.   NATURE

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Fucose-deficient hematopoietic stem cells have decreased self-renewal and aberrant marrow niche occupancy

(2010) Jay Myers et al.   TRANSFUSION

Functional Heterogeneity of the Bone Marrow Vascular Niche

(2009) Hans-Georg Kopp et al.   Annals of the New York Academy of Sciences

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization

(2009) M. J. Christopher et al.   BLOOD

Notch-dependent control of myelopoiesis is regulated by fucosylation

(2008) L. Zhou et al.   BLOOD

In vivo consequences of deleting EGF repeats 8–12 including the ligand binding domain of mouse Notch1

(2008) Changhui Ge et al.   BMC DEVELOPMENTAL BIOLOGY

The Transcription Factor EGR1 Controls Both the Proliferation and Localization of Hematopoietic Stem Cells

(2008) Irene M. Min et al.   Cell Stem Cell

Pofut1 is required for the proper localization of the Notch receptor during mouse development

(2008) Yoshiaki Okamura et al.   MECHANISMS OF DEVELOPMENT

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

(2008) Matthew J Hilton et al.   NATURE MEDICINE

The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development

(2008) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA