Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity

C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

(2015) Guillaume Hoeffel et al.   IMMUNITY

Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition

(2015) Carlos O. Lizama et al.   Nature Communications

Distinct Sources of Hematopoietic Progenitors Emerge before HSCs and Provide Functional Blood Cells in the Mammalian Embryo

(2015) Kathleen E. McGrath et al.   Cell Reports

Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo

(2014) L. Padron-Barthe et al.   BLOOD

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

(2014) K. S. Potts et al.   BLOOD

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs

(2013) S. Gordon-Keylock et al.   BLOOD

Erythro-myeloid progenitors: “Definitive” hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells

(2013) Jenna M. Frame et al.   BLOOD CELLS MOLECULES AND DISEASES

Retinoic Acid Signaling Is Essential for Embryonic Hematopoietic Stem Cell Development

(2013) Bhaskar Chanda et al.   CELL

Lymphomyeloid Contribution of an Immune-Restricted Progenitor Emerging Prior to Definitive Hematopoietic Stem Cells

(2013) Charlotta Böiers et al.   Cell Stem Cell

Regulation of Endothelial Cell Differentiation and Specification

(2013) Kathrina L. Marcelo et al.   CIRCULATION RESEARCH

Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells

(2013) J. Tober et al.   DEVELOPMENT

BRG1 promotes COUP-TFII expression and venous specification during embryonic vascular development

(2013) R. B. Davis et al.   DEVELOPMENT

Dynamic responses of endothelial cells to changes in blood flow during vascular remodeling of the mouse yolk sac

(2013) Ryan S. Udan et al.   DEVELOPMENT

Expression levels of endoglin distinctively identify hematopoietic and endothelial progeny at different stages of yolk sac hematopoiesis

(2013) Luciene Borges et al.   STEM CELLS

Sox17 is indispensable for acquisition and maintenance of arterial identity

(2013) Monica Corada et al.   Nature Communications

Haemogenic endocardium contributes to transient definitive haematopoiesis

(2013) Haruko Nakano et al.   Nature Communications

Direct confocal acquisition of fluorescence from X-gal staining on thick tissue sections

(2013) Konstantin L. Levitsky et al.   Scientific Reports

Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence

(2012) M. Yoshimoto et al.   BLOOD

Hematopoietic stem cell development requires transient Wnt/β-catenin activity

(2012) Cristina Ruiz-Herguido et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dual Lineage-Specific Expression of Sox17 During Mouse Embryogenesis

(2012) Eunyoung Choi et al.   STEM CELLS

Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters

(2011) T. Yokomizo et al.   BLOOD

A transient definitive erythroid lineage with unique regulation of the  -globin locus in the mammalian embryo

(2011) K. E. McGrath et al.   BLOOD

Erythroid/Myeloid Progenitors and Hematopoietic Stem Cells Originate from Distinct Populations of Endothelial Cells

(2011) Michael J. Chen et al.   Cell Stem Cell

Embryonic day 9 yolk sac and intra-embryonic hemogenic endothelium independently generate a B-1 and marginal zone progenitor lacking B-2 potential

(2011) M. Yoshimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels

(2011) C. T. Griffin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells

(2010) E. Y. N. Lam et al.   BLOOD

The Role of Wnt Signaling in Physiological and Pathological Angiogenesis

(2010) Elisabetta Dejana   CIRCULATION RESEARCH

Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos

(2010) T. Yokomizo et al.   DEVELOPMENT

The Wnt/β-Catenin Pathway Modulates Vascular Remodeling and Specification by Upregulating Dll4/Notch Signaling

(2010) Monica Corada et al.   DEVELOPMENTAL CELL

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

(2010) Jean-Charles Boisset et al.   NATURE

Blood stem cells emerge from aortic endothelium by a novel type of cell transition

(2010) Karima Kissa et al.   NATURE

Haematopoietic stem cells derive directly from aortic endothelium during development

(2010) Julien Y. Bertrand et al.   NATURE

Hematopoietic Stem Cell Development Is Dependent on Blood Flow

(2009) Trista E. North et al.   CELL

Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration

(2009) Wolfram Goessling et al.   CELL

Arterial–Venous Specification During Development

(2009) Matthew R. Swift et al.   CIRCULATION RESEARCH

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

Continuous single-cell imaging of blood generation from haemogenic endothelium

(2009) Hanna M. Eilken et al.   NATURE

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

(2009) Christophe Lancrin et al.   NATURE

Biomechanical forces promote embryonic haematopoiesis

(2009) Luigi Adamo et al.   NATURE

Quantitative image based apoptotic index measurement using multispectral imaging flow cytometry: a comparison with standard photometric methods

(2008) Shannon Henery et al.   APOPTOSIS

Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis

(2008) L. C. Goldie et al.   BLOOD

Runx1 is involved in primitive erythropoiesis in the mouse

(2008) T. Yokomizo et al.   BLOOD

Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells

(2008) Ann C. Zovein et al.   Cell Stem Cell

Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast

(2008) X. Cheng et al.   DEVELOPMENT

All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac

(2007) C. T. Lux et al.   BLOOD