Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation

Primary cilia mediate sonic hedgehog signaling to regulate neuronal-like differentiation of bone mesenchymal stem cells for resveratrol induction in vitro

(2014) Jia-Gui Huang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment

(2014) Mu He et al.   NATURE CELL BIOLOGY

Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes

(2014) C.L. Thompson et al.   OSTEOARTHRITIS AND CARTILAGE

Primary cilium-associated genes mediate bone marrow stromal cell response to hypoxia

(2014) James A.L. Brown et al.   Stem Cell Research

IFT80 is essential for chondrocyte differentiation by regulating Hedgehog and Wnt signaling pathways

(2013) Changdong Wang et al.   EXPERIMENTAL CELL RESEARCH

Primary Cilia: The Chemical Antenna Regulating Human Adipose-Derived Stem Cell Osteogenesis

(2013) Josephine C. Bodle et al.   PLoS One

Surface topography regulates wnt signaling through control of primary cilia structure in mesenchymal stem cells

(2013) R. J. McMurray et al.   Scientific Reports

TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

(2013) Christian Alexandro Clement et al.   Cell Reports

The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis

(2012) Shuying Yang et al.   BONE

BBS-Induced Ciliary Defect Enhances Adipogenesis, Causing Paradoxical Higher-Insulin Sensitivity, Glucose Usage, and Decreased Inflammatory Response

(2012) Vincent Marion et al.   Cell Metabolism

Primary Cilia-Mediated Mechanotransduction in Human Mesenchymal Stem Cells

(2012) David A. Hoey et al.   STEM CELLS

A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development

(2011) Ellen J. Ezratty et al.   CELL

Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia

(2011) J. B. Wallingford et al.   GENES & DEVELOPMENT

Ciliopathies

(2011) Friedhelm Hildebrandt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mechanical loading modulates chondrocyte primary cilia incidence and length

(2010) Susan R McGlashan et al.   CELL BIOLOGY INTERNATIONAL

The Role of Primary Cilia in Mesenchymal Stem Cell Differentiation: A Pivotal Switch in Guiding Lineage Commitment

(2010) Padmaja Tummala et al.   Cellular and Molecular Bioengineering

Identification of Signaling Pathways Regulating Primary Cilium Length and Flow-Mediated Adaptation

(2010) Tatiana Y. Besschetnova et al.   CURRENT BIOLOGY

Cell shape and contractility regulate ciliogenesis in cell cycle–arrested cells

(2010) Amandine Pitaval et al.   JOURNAL OF CELL BIOLOGY

The primary cilium at a glance

(2010) P. Satir et al.   JOURNAL OF CELL SCIENCE

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Kif3a Deficiency Reverses the Skeletal Abnormalities in Pkd1 Deficient Mice by Restoring the Balance Between Osteogenesis and Adipogenesis

(2010) Ni Qiu et al.   PLoS One

The Primary Cilium as a Complex Signaling Center

(2009) Nicolas F. Berbari et al.   CURRENT BIOLOGY

Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes

(2009) D. Zhu et al.   JOURNAL OF CELL SCIENCE

Primary Cilia and Signaling Pathways in Mammalian Development, Health and Disease

(2009) Iben R. Veland et al.   NEPHRON PHYSIOLOGY

Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation

(2009) Vincent Marion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Hedgehog Signaling Inhibits Osteoblast Differentiation of Human Mesenchymal Stem Cells

(2008) Magali Plaisant et al.   STEM CELLS