Undifferentiated State Induced by Rb-p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts

Inhibition of Pluripotency Networks by the Rb Tumor Suppressor Restricts Reprogramming and Tumorigenesis

(2015) Michael S. Kareta et al.   Cell Stem Cell

ATM Mediates pRB Function To Control DNMT1 Protein Stability and DNA Methylation

(2013) Awad Shamma et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of FDA-approved Drugs Targeting Breast Cancer Stem Cells Along With Biomarkers of Sensitivity

(2013) Poornima Bhat-Nakshatri et al.   Scientific Reports

Twists in views on RB functions in cellular signaling, metabolism and stem cells

(2012) Chiaki Takahashi et al.   CANCER SCIENCE

Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells

(2012) Eleftherios Sachlos et al.   CELL

The retinoblastoma tumor suppressor and stem cell biology

(2012) J. Sage   GENES & DEVELOPMENT

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

The RB family is required for the self-renewal and survival of human embryonic stem cells

(2012) Jamie F. Conklin et al.   Nature Communications

A Functional Role for Tumor Cell Heterogeneity in a Mouse Model of Small Cell Lung Cancer

(2011) Joaquim Calbo et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Local Mesenchymal Stem/Progenitor Cells Are a Preferential Target for Initiation of Adult Soft Tissue Sarcomas Associated with p53 and Rb Deficiency

(2010) Jinhyang Choi et al.   AMERICAN JOURNAL OF PATHOLOGY

A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs

(2010) Jonghwan Kim et al.   CELL

Apoptotic Caspases Regulate Induction of iPSCs from Human Fibroblasts

(2010) Fang Li et al.   Cell Stem Cell

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

(2010) Payman Samavarchi-Tehrani et al.   Cell Stem Cell

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status

(2010) Zhe Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural Basis of Human CYP51 Inhibition by Antifungal Azoles

(2010) Natallia Strushkevich et al.   JOURNAL OF MOLECULAR BIOLOGY

Rb regulates fate choice and lineage commitment in vivo

(2010) Eliezer Calo et al.   NATURE

Reversion-inducing cysteine-rich protein with Kazal motifs interferes with epidermal growth factor receptor signaling

(2010) S Kitajima et al.   ONCOGENE

In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach

(2009) Lukas Chavez et al.   BMC GENOMICS

Rb Regulates DNA Damage Response and Cellular Senescence through E2F-Dependent Suppression of N-Ras Isoprenylation

(2009) Awad Shamma et al.   CANCER CELL

Mouse Fibroblasts Lacking RB1 Function Form Spheres and Undergo Reprogramming to a Cancer Stem Cell Phenotype

(2009) Yongqing Liu et al.   Cell Stem Cell

A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A

(2009) Xin Zhang et al.   JOURNAL OF CELL BIOLOGY

Keeping an eye on retinoblastoma control of human embryonic stem cells

(2009) Jamie F. Conklin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

(2009) Teruhisa Kawamura et al.   NATURE

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

(2008) Ittai Ben-Porath et al.   NATURE GENETICS