Endocannabinoids in Synaptic Plasticity and Neuroprotection

Δ9-THC-Caused Synaptic and Memory Impairments Are Mediated through COX-2 Signaling

(2013) Rongqing Chen et al.   CELL

Chronic Traumatic Encephalopathy

(2013) Juneyoung Yi et al.   Current Sports Medicine Reports

Chronic neuropathologies of single and repetitive TBI: substrates of dementia?

(2013) Douglas H. Smith et al.   Nature Reviews Neurology

The clinical spectrum of sport-related traumatic brain injury

(2013) Barry D. Jordan   Nature Reviews Neurology

Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers

(2013) Steven T. DeKosky et al.   Nature Reviews Neurology

Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood

(2013) Henrik Zetterberg et al.   Nature Reviews Neurology

Chronic traumatic encephalopathy – neuropathology in athletes and war veterans

(2013) Nelli Lakis et al.   NEUROLOGICAL RESEARCH

A Cortico-Hippocampal Learning Rule Shapes Inhibitory Microcircuit Activity to Enhance Hippocampal Information Flow

(2013) Jayeeta Basu et al.   NEURON

The Role of Markers of Inflammation in Traumatic Brain Injury

(2013) Thomas Woodcock et al.   Frontiers in Neurology

The spectrum of disease in chronic traumatic encephalopathy

(2012) Ann C. McKee et al.   BRAIN

Cannabinoid Receptors and Endocannabinoids: Role in Neuroinflammatory and Neurodegenerative Disorders

(2012) Tiziana Bisogno et al.   CNS & Neurological Disorders-Drug Targets

Selective Inhibition of Alpha/Beta-Hydrolase Domain 6 Attenuates Neurodegeneration, Alleviates Blood Brain Barrier Breakdown, and Improves Functional Recovery in a Mouse Model of Traumatic Brain Injury

(2012) Flaubert Tchantchou et al.   JOURNAL OF NEUROTRAUMA

Long-lasting potentiation of hippocampal synaptic transmission by direct cortical input is mediated via endocannabinoids

(2012) Jian-Yi Xu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Therapeutic potential of monoacylglycerol lipase inhibitors

(2012) Melinda M. Mulvihill et al.   LIFE SCIENCES

CB2 receptor and amyloid pathology in frontal cortex of Alzheimer's disease patients

(2012) Maite Solas et al.   NEUROBIOLOGY OF AGING

The Neuropathology and Neurobiology of Traumatic Brain Injury

(2012) Kaj Blennow et al.   NEURON

Endocannabinoid Signaling and Synaptic Function

(2012) Pablo E. Castillo et al.   NEURON

A Dysregulated Endocannabinoid-Eicosanoid Network Supports Pathogenesis in a Mouse Model of Alzheimer's Disease

(2012) Justin R. Piro et al.   Cell Reports

Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease

(2012) Rongqing Chen et al.   Cell Reports

Molecular reorganization of endocannabinoid signalling in Alzheimer’s disease

(2011) Jan Mulder et al.   BRAIN

Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ

(2011) Huizhi Du et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endocannabinoids and traumatic brain injury

(2011) Esther Shohami et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults

(2011) X. Chen et al.   NEUROSCIENCE

Endocannabinoids and Retrograde Modulation of Synaptic Transmission

(2011) Takako Ohno-Shosaku et al.   NEUROSCIENTIST

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

(2011) D. K. Nomura et al.   SCIENCE

The endocannabinoid system as a target for the treatment of neurodegenerative disease

(2010) Emma L Scotter et al.   BRITISH JOURNAL OF PHARMACOLOGY

Novel Natural and Synthetic Ligands of the Endocannabinoid System

(2010) Lumir Hanus et al.   CURRENT MEDICINAL CHEMISTRY

From Surface to Nuclear Receptors: The Endocannabinoid Family Extends its Assets

(2010) M. Pistis et al.   CURRENT MEDICINAL CHEMISTRY

Synaptic stability and plasticity in a floating world

(2010) Kimberly Gerrow et al.   CURRENT OPINION IN NEUROBIOLOGY

Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury

(2010) Andrew Sauerbeck et al.   EXPERIMENTAL NEUROLOGY

Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice

(2010) Y. Gao et al.   JOURNAL OF NEUROSCIENCE

Dynamic changes of anandamide in the cerebrospinal fluid of Parkinson's disease patients

(2010) Valerio Pisani et al.   MOVEMENT DISORDERS

The endocannabinoid 2-arachidonoylglycerol reduces lesion expansion and white matter damage after spinal cord injury

(2010) Angel Arevalo-Martin et al.   NEUROBIOLOGY OF DISEASE

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

Endocannabinoids Differentially Modulate Synaptic Plasticity in Rat Hippocampal CA1 Pyramidal Neurons

(2010) Jian-Yi Xu et al.   PLoS One

Characterization of Monoacylglycerol Lipase Inhibition Reveals Differences in Central and Peripheral Endocannabinoid Metabolism

(2009) Jonathan Z. Long et al.   CHEMISTRY & BIOLOGY

The Role of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) in Alzheimer’s Disease

(2009) Qingguang Jiang et al.   CNS DRUGS

Cannabinoid activation of peroxisome proliferator-activated receptors: Potential for modulation of inflammatory disease

(2009) S.E. O'Sullivan et al.   IMMUNOBIOLOGY

Blockade of 2-Arachidonoylglycerol Hydrolysis by Selective Monoacylglycerol Lipase Inhibitor 4-Nitrophenyl 4-(Dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances Retrograde Endocannabinoid Signaling

(2009) B. Pan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Neuroinflammation and Memory: The Role of Prostaglandins

(2009) Amy M. Hein et al.   MOLECULAR NEUROBIOLOGY

Monoacylglycerol Lipase Limits the Duration of Endocannabinoid-Mediated Depolarization-Induced Suppression of Excitation in Autaptic Hippocampal Neurons

(2009) A. Straiker et al.   MOLECULAR PHARMACOLOGY

Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease

(2009) Tomohiko Sato et al.   NEUROBIOLOGY OF AGING

Functional CB2 type cannabinoid receptors at CNS synapses

(2009) Nicola H. Morgan et al.   NEUROPHARMACOLOGY

Endocannabinoid-Mediated Control of Synaptic Transmission

(2009) Masanobu Kano et al.   PHYSIOLOGICAL REVIEWS

PPARγ agonist rosiglitazone is neuroprotective after traumatic brain injury via anti-inflammatory and anti-oxidative mechanisms

(2008) Jae-Hyuk Yi et al.   BRAIN RESEARCH

Toll-like receptor 4 mediates cross-talk between peroxisome proliferator-activated receptor γ and nuclear factor-κB in macrophages

(2008) Brian M. Necela et al.   IMMUNOLOGY

Endocannabinoid 2-Arachidonoylglycerol Protects Neurons by Limiting COX-2 Elevation

(2008) Jian Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Cortical Inputs Erase Long-Term Potentiation at Schaffer Collateral Synapses

(2008) Y. Izumi et al.   JOURNAL OF NEUROSCIENCE

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

(2008) Jonathan Z Long et al.   Nature Chemical Biology

Impaired Spatial Representation in CA1 after Lesion of Direct Input from Entorhinal Cortex

(2008) Vegard Heimly Brun et al.   NEURON

Endocannabinoid signaling in microglial cells

(2008) Nephi Stella   NEUROPHARMACOLOGY

Regulation of excitability and plasticity by endocannabinoids and PKA in developing hippocampus

(2008) H. Yasuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biology of endocannabinoid synthesis system

(2008) Jun Wang et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

PPARs in Alzheimer's Disease

(2008) Markus P. Kummer et al.   PPAR Research

PPAR Regulation of Inflammatory Signaling in CNS Diseases

(2008) John J. Bright et al.   PPAR Research

PPARs in Neuroinflammation

(2008) Michael K. Racke et al.   PPAR Research

CB2receptors in the brain: role in central immune function

(2007) G A Cabral et al.   BRITISH JOURNAL OF PHARMACOLOGY

Interaction of ligands for the peroxisome proliferator-activated receptor γ with the endocannabinoid system

(2007) A Lenman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors

(2007) S E O'Sullivan   BRITISH JOURNAL OF PHARMACOLOGY

Role of the cyclic-AMP/PKA cascade and of P/Q-type Ca++ channels in endocannabinoid-mediated long-term depression in the nucleus accumbens

(2007) Susana Mato et al.   NEUROPHARMACOLOGY