Article
Chemistry, Multidisciplinary
Yi-fei Liu, Lei Zhang, Qi Wu, Lin-yin Feng
Summary: The study found that Paeoniflorin protects primary rat cortical neurons from ischemic brain injury by maintaining HDAC4 subcellular localization, reducing caspase3 activity, and increasing the expression of protective proteins such as GDNF.
ACTA PHARMACOLOGICA SINICA
(2022)
Article
Neurosciences
Dazhuang Yi, Qunhui Wang, Yuhao Zhao, Yu Song, Hong You, Jian Wang, Renjie Liu, Zhongqiang Shi, Xuan Chen, Qi Luo
Summary: The study identified alterations in the m6A modification profile in cerebral ischemia-reperfusion injury model rats, leading to differential gene expression associated with inflammation and neuronal pathways. Among m6A regulators, FTO was specifically downregulated in neurons after MCAO/R, providing new insights into the mechanisms of cerebral ischemia-reperfusion injury.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Computer Science, Interdisciplinary Applications
Ancor Sanz-Garcia, Miriam Perez-Romero, Guillermo J. Ortega
Summary: This study aims to characterize seizure types and phases based on electrophysiological characteristics. By analyzing intracranial EEG recordings, network and spectral measures were calculated and used to identify and classify seizure types and phases. The results showed that seizure types could be classified with high accuracy using a multidimensional feature space and a support vector machine. The study also revealed specific measures and patterns related to seizure severity during different seizure phases.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Vibeke Bay, Nina K. Iversen, Seyedeh Marziyeh Jabbari Shiadeh, R. Andrew Tasker, Gregers Wegener, Maryam Ardalan
Summary: Transient cerebral ischemia followed by reperfusion in an infarcted brain results in predictable morphological changes in neuronal and non-neuronal cells. Accurately delineating the cerebral infarct is challenging, but using a macroscopic histological approach can lead to faster and more reliable preclinical research results. The study found that the MAP2 staining method can reliably identify the ischemic area macroscopically in cryo-preserved and paraffin-embedded brain sections, regardless of immersion-fixed or perfusion-fixed brains.
JOURNAL OF CHEMICAL NEUROANATOMY
(2021)
Article
Clinical Neurology
Aron T. Hill, Itay Hadas, Reza Zomorrodi, Daphne Voineskos, Paul B. Fitzgerald, Daniel M. Blumberger, Zafiris J. Daskalakis
Summary: This study utilized TMS-EEG to investigate the differences in neural oscillatory dynamics between subjects with major depressive disorder (MDD) and healthy controls (HC), revealing increased oscillatory power in the DLPFC area in MDD subjects before treatment, and decreased power after convulsive therapy. These findings suggest that convulsive therapy may modulate neural oscillatory activity in MDD.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Cell Biology
Dabao Yao, Shuo Zhang, Zhengwei Hu, Haiyang Luo, Chengyuan Mao, Yu Fan, Mibo Tang, Fen Liu, Si Shen, Liyuan Fan, Mengjie Li, Jingjing Shi, Jiadi Li, Dongrui Ma, Yuming Xu, Changhe Shi
Summary: The study showed that overexpression of CHIP may exert neuroprotective effects by attenuating necroptosis and inflammation during CIR injury.
Article
Neurosciences
Manping Yang, Yunying Wang, Shiquan Wang, Yaru Guo, Ting Gu, Liwen Shi, Junbao Zhang, Xiaoshuang Tuo, Xiaoyu Liu, Minjuan Zhang, Jiao Deng, Zongping Fang, Zhihong Lu
Summary: The mechanism of electroacupuncture (EA) pretreatment-induced neuroprotection remains unclear. In this study, the researchers found that neuronal expression of TREM2 was increased after ischemia/reperfusion. Knockdown of TREM2 in excitatory neurons resulted in neurological damage and increased infarct volume. EA pretreatment enhanced TREM2 expression and improved autophagic flux, and these effects were abolished by TREM2 knockdown.
BRAIN RESEARCH BULLETIN
(2023)
Article
Neurosciences
Junling Wang, Bin Jing, Ru Liu, Donghong Li, Wei Wang, Jiaoyang Wang, Jianfeng Lei, Yue Xing, Jiaqing Yan, Horace H. Loh, Guangming Lu, Xiaofeng Yang
Summary: This study demonstrated the potential of simultaneous EEG-fMRI recording as a noninvasive clinical diagnostic technique for localizing the EZ or SOZ. The results showed a high spatial consistency between BOLD responses and the SOZ, indicating its effectiveness in mapping epileptic networks.
Article
Neurosciences
Sahlia Joseph-Pauline, Nathan Morrison, Michael Braccia, Alana Payne, Lindsay Gugerty, Jesse Mostoller, Paul Lecker, E-jine Tsai, Jessica Kim, Mark Martin, Rushil Brahmbhatt, Grzegorz Gorski, Jacquelyn Gerhart, Mindy George-Weinstein, Jonathan Stone, Sivaraman Purushothuman, Arturo Bravo-Nuevo
Summary: Myo/Nog cells rapidly respond to brain injury and their increased numbers within the lesion have a neuroprotective effect by reducing cell death and promoting the survival of neurons.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Medicine, Research & Experimental
Mario Campanile, Ornella Cuomo, Paola Brancaccio, Antonio Vinciguerra, Antonella Casamassa, Olga Pastorino, Floriana Volpicelli, Maria Teresa Gentile, Salvatore Amoroso, Lucio Annunziato, Luca Colucci-D'Amato, Giuseppe Pignataro
Summary: This study evaluated the protective effect of Ruta graveolens water extract (RGWE) in an in vivo experimental model of brain ischemia. It was found that RGWE containing the major component Rutin could ameliorate ischemic damage and improve neurological performances, while reducing inflammatory responses of astrocytes and microglia.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Behavioral Sciences
Lichao Fan, Lichun Zhou
Summary: AG490 acts as a JAK antagonist showing both anti-apoptotic and neuroprotective effects in cerebral ischemia/reperfusion injury. It achieves the anti-apoptotic effect through regulating the JAK-STAT pathway and enhancing the expression of neurotrophins.
BRAIN AND BEHAVIOR
(2021)
Article
Computer Science, Artificial Intelligence
Yanna Zhao, Gaobo Zhang, Changxu Dong, Qi Yuan, Fangzhou Xu, Yuanjie Zheng
Summary: A novel seizure detection method based on graph attention network (GAT) is proposed to effectively utilize the positional relationships between different EEG signals and address the data imbalance issue. Experimental results show that the proposed method achieves high accuracy, sensitivity, and specificity.
INTERNATIONAL JOURNAL OF NEURAL SYSTEMS
(2021)
Article
Clinical Neurology
Ingmar Blumcke, Fernando Cendes, Hajime Miyata, Maria Thom, Eleonora Aronica, Imad Najm
Summary: FCD is the most common cause of drug-resistant focal epilepsy in children and young adults, and the diagnosis relies on histopathological assessment of surgical brain tissue. Challenges exist in diagnosing FCD and its subtypes, necessitating continuous research and consensus for a reliable classification scheme. Combining clinical, imaging, histopathology, and molecular studies will help define the disease spectrum and develop specific treatment options for FCD.
Article
Computer Science, Artificial Intelligence
Yanna Zhao, Mingrui Xue, Changxu Dong, Jiatong He, Dengyu Chu, Gaobo Zhang, Fangzhou Xu, Xinting Ge, Yuanjie Zheng
Summary: This article introduces an automatic seizure identification method based on brain connectivity learning, which demonstrates high performance and stability on different patients.
INTERNATIONAL JOURNAL OF NEURAL SYSTEMS
(2022)
Article
Endocrinology & Metabolism
Michael D. Weiss, Silvia Carloni, Tania Vanzolini, Sofia Coppari, Walter Balduini, Giuseppe Buonocore, Mariangela Longini, Serafina Perrone, Livia Sura, Atefeh Mohammadi, Marco Bruno Luigi Rocchi, Massimo Negrini, Davide Melandri, Maria Cristina Albertini
Summary: This study analyzed animal and human specimens to identify common pathways in neonatal encephalopathy (NE) and validate them through protein expression. The method provides a better understanding of the pathophysiology in NE and improves the knowledge about potential therapeutic options.
JOURNAL OF PINEAL RESEARCH
(2022)
Article
Engineering, Biomedical
Chunyan Li, Raj K. Narayan, Pei-Ming Wu, Neena Rajan, Zhizhen Wu, Neal Mehan, Eugene V. Golanov, Chong H. Ahn, Jed A. Hartings
JOURNAL OF NEURAL ENGINEERING
(2016)
Article
Endocrinology & Metabolism
Maren K. L. Winkler, Nora Dengler, Nils Hecht, Jed A. Hartings, Eun J. Kang, Sebastian Major, Peter Martus, Peter Vajkoczy, Johannes Woitzik, Jens P. Dreier
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2017)
Article
Endocrinology & Metabolism
Jed A. Hartings, Chunyan Li, Jason M. Hinzman, C. William Shuttleworth, Griffin L. Ernst, Jens P. Dreier, J. Adam Wilson, Norberto Andaluz, Brandon Foreman, Andrew P. Carlson
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2017)
Article
Endocrinology & Metabolism
Chunyan Li, Raj K. Narayan, Ping Wang, Jed A. Hartings
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2017)
Review
Endocrinology & Metabolism
Jens P. Dreier, Martin Fabricius, Cenk Ayata, Oliver W. Sakowitz, C. William Shuttleworth, Christian Dohmen, Rudolf Graf, Peter Vajkoczy, Raimund Helbok, Michiyasu Suzuki, Alois J. Schiefecker, Sebastian Major, Maren K. L. Winkler, Eun-Jeung Kang, Denny Milakara, Ana I. Oliveira-Ferreira, Clemens Reiffurth, Gajanan S. Revankar, Kazutaka Sugimoto, Nora F. Dengler, Nils Hecht, Brandon Foreman, Bart Feyen, Daniel Kondziella, Christian K. Friberg, Henning Piilgaard, Eric S. Rosenthal, M. Brandon Westover, Anna Maslarova, Edgar Santos, Daniel Hertle, Renan Sanchez-Porras, Sharon L. Jewell, Baptiste Balanca, Johannes Platz, Jason M. Hinzman, Janos Lueckl, Karl Schoknecht, Michael Schoell, Christoph Drenckhahn, Delphine Feuerstein, Nina Eriksen, Viktor Horst, Julia S. Bretz, Paul Jahnke, Michael Scheel, Georg Bohner, Egill Rostrup, Bente Pakkenberg, Uwe Heinemann, Jan Claassen, Andrew P. Carlson, Christina M. Kowoll, Svetlana Lublinsky, Yoash Chassidim, Ilan Shelef, Alon Friedman, Gerrit Brinker, Michael Reiner, Sergei A. Kirov, R. David Andrew, Eszter Farkas, Erdem Gueresir, Hartmut Vatter, Lee S. Chung, K. C. Brennan, Thomas Lieutaud, Stephane Marinesco, Andrew I. R. Maas, Juan Sahuquillo, Markus A. Dahlem, Frank Richter, Oscar Herreras, Martyn G. Boutelle, David O. Okonkwo, M. Ross Bullock, Otto W. Witte, Peter Martus, Arn M. J. M. van den Maagdenberg, Michel D. Ferrari, Rick M. Dijkhuizen, Lori A. Shutter, Norberto Andaluz, Andre P. Schulte, Brian MacVicar, Tomas Watanabe, Johannes Woitzik, Martin Lauritzen, Anthony J. Strong, Jed A. Hartings
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2017)
Review
Endocrinology & Metabolism
Jed A. Hartings, C. William Shuttleworth, Sergei A. Kirov, Cenk Ayata, Jason M. Hinzman, Brandon Foreman, R. David Andrew, Martyn G. Boutelle, K. C. Brennan, Andrew P. Carlson, Markus A. Dahlem, Christoph Drenckhahn, Christian Dohmen, Martin Fabricius, Eszter Farkas, Delphine Feuerstein, Rudolf Graf, Raimund Helbok, Martin Lauritzen, Sebastian Major, Ana I. Oliveira-Ferreira, Frank Richter, Eric S. Rosenthal, Oliver W. Sakowitz, Renan Sanchez-Porras, Edgar Santos, Michael Scholl, Anthony J. Strong, Anja Urbach, M. Brandon Westover, Maren K. L. Winkler, Otto W. Witte, Johannes Woitzik, Jens P. Dreier
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2017)
Editorial Material
Endocrinology & Metabolism
Jed A. Hartings, Jens P. Dreier
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2017)
Article
Endocrinology & Metabolism
Alexandra Pinczolits, Anna Zdunczyk, Nora F. Dengler, Nils Hecht, Christina M. Kowoll, Christian Dohmen, Rudolf Graf, Maren K. L. Winkler, Sebastian Major, Jed A. Hartings, Jens P. Dreier, Peter Vajkoczy, Johannes Woitzik
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2017)
Review
Clinical Neurology
Andrew I. R. Maas, David K. Menon, P. David Adelson, Nada Andelic, Michael J. Bell, Antonio Belli, Peter Bragge, Alexandra Brazinova, Andras Buerki, Randall M. Chesnut, Giuseppe Citerio, Mark Coburn, D. Jamie Cooper, A. Tamara Crowder, Endre Czeiter, Marek Czosnyka, Ramon Diaz-Arrastia, Jens P. Dreier, Ann-Christine Duhaime, Ari Ercole, Thomas A. van Essen, Valery L. Feigin, Guoyi Gao, Joseph Giacino, Laura E. Gonzalez-Lara, Russell L. Gruen, Deepak Gupta, Jed A. Hartings, Sean Hill, Ji-yao Jiang, Naomi Ketharanathan, Erwin J. O. Kompanje, Linda Lanyon, Steven Laureys, Fiona Lecky, Harvey Levin, Hester F. Lingsma, Marc Maegele, Marek Majdan, Geoffrey Manley, Jill Marsteller, Luciana Mascia, Charles McFadyen, Stefania Mondello, Virginia Newcombe, Aarno Palotie, Paul M. Parizel, Wilco Peul, James Piercy, Suzanne Polinder, Louis Puybasset, Todd E. Rasmussen, Rolf Rossaint, Peter Smielewski, Jeannette Soderberg, Simon J. Stanworth, Murray B. Stein, Nicole von Steinbuechel, William Stewart, Ewout W. Steyerberg, Nino Stocchetti, Anneliese Synnot, Braden Te Ao, Olli Tenovuo, Alice Theadom, Dick Tibboel, Walter Videtta, Kevin K. W. Wang, W. Huw Williams, Lindsay Wilson, Kristine Yaffe
Article
Neuroimaging
Denny Milakara, Cristian Grozea, Markus Dahlem, Sebastian Major, Maren K. L. Winkler, Janos Lueckl, Michael Scheel, Vasilis Kola, Karl Schoknecht, Svetlana Lublinsky, Alon Friedman, Peter Martus, Jed A. Hartings, Johannes Woitzik, Jens P. Dreier
NEUROIMAGE-CLINICAL
(2017)
Article
Clinical Neurology
Jens P. Dreier, Sebastian Major, Brandon Foreman, Maren K. L. Winkler, Eun-Jeung Kang, Denny Milakara, Coline L. Lemale, Vince DiNapoli, Jason M. Hinzman, Johannes Woitzik, Norberto Andaluz, Andrew Carlson, Jed A. Hartings
ANNALS OF NEUROLOGY
(2018)
Article
Clinical Neurology
Jed A. Hartings, Jonathan York, Christopher P. Carroll, Jason M. Hinzman, Eric Mahoney, Bryan Krueger, Maren K. L. Winkler, Sebastian Major, Viktor Horst, Paul Jahnke, Johannes Woitzik, Vasilis Kola, Yifeng Du, Matthew Hagen, Jianxiong Jiang, Jens P. Dreier
Article
Critical Care Medicine
Maryse C. Cnossen, Jilske A. Huijben, Mathieu van der Jagt, Victor Volovici, Thomas van Essen, Suzanne Polinder, David Nelson, Ari Ercole, Nino Stocchetti, Giuseppe Citerio, Wilco C. Peul, Andrew I. R. Maas, David Menon, Ewout W. Steyerberg, Hester F. Lingsma
Review
Critical Care Medicine
Jed A. Hartings
CURRENT OPINION IN CRITICAL CARE
(2017)
Proceedings Paper
Engineering, Biomedical
Zhizhen Wu, Chunyan Li, Jed Hartings, Raj K. Narayan, Chong Ahn
2016 38TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
(2016)
Article
Neurosciences
Song Xue, Feng Kong, Yiying Song, Jia Liu
Summary: This study used resting-state functional magnetic resonance imaging to explore the relationship between individual's spontaneous neural activity and social interaction anxiety in a nonclinical population. The results showed that social interaction anxiety was correlated with the fractional amplitude of low-frequency fluctuations in several brain regions, and that emotional intelligence partially mediated this relationship. This study provides evidence for the neural basis of social interaction anxiety in the normal population and highlights the role of emotional intelligence in this anxiety.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Katsuyuki Yamaguchi, Takuya Yazawa
Summary: This study provides morphometric data on the development of the human medullary arcuate nucleus (AN) by examining the brains of preterm and perinatal infants. The results show that AN morphology demonstrates asymmetry and individual variability during the fetal period. The volume and neuronal number of AN increase exponentially with age, while neuronal density decreases exponentially. The AN may undergo neuron death and neuroblasts production after mid-gestation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zhan Zhou, Weixin Dai, Tianxiao Liu, Min Shi, Yi Wei, Lifei Chen, Yubo Xie
Summary: Studies have shown that propofol-induced neurotoxicity is caused by disruption of mitochondrial fission and fusion, leading to an energy supply imbalance for developing neurons. Healthy mitochondria released by astrocytes can migrate to compromised neurons to mitigate propofol-induced neurotoxicity, but the exact mechanisms involved still need further clarification.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
An Chen, Song Hao, Yongpeng Han, Yang Fang, Yibei Miao
Summary: This study explores the efficacy of two forms of BCI attention training games and finds that physical games may be more effective than video games. The research also offers valuable insights for future game design from a neuroscience perspective.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lina Liu, Luran Liu, Yunting Lu, Tianyuan Zhang, Wenting Zhao
Summary: This study reveals that GDI1 serves as a potential diagnostic biomarker for AD and inhibition of GDI1 can attenuate Aβ-induced neurotoxicity. The findings offer new insights for the treatment of AD.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zahra Gholami, Ava Soltani Hekmat, Ali Abbasi, Kazem Javanmardi
Summary: This study investigated the effects of alamandine on allodynia in a rat model and found the presence of MrgD receptors in the vlPAG and RVM regions. Microinjection of alamandine resulted in a significant increase in paw withdrawal threshold and could be blocked by an MrgD receptor antagonist. Upregulation of MrgD receptor expression following allodynia induction suggests a potential compensatory mechanism in response to pain.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Mingliang Xu, Lei Xia, Junjie Li, Yehong Du, Zhifang Dong
Summary: This study found that DHF effectively alleviates sevoflurane-induced cognitive impairment in developing mice by restoring the balance between tau O-GlcNAcylation and phosphorylation. Therefore, DHF has the potential to be a therapeutic agent for treating cognitive impairment associated with anesthetics, such as sevoflurane.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Tsubasa Mitsutake, Hisato Nakazono, Takanori Taniguchi, Hisayoshi Yoshizuka, Maiko Sakamoto
Summary: The posterior parietal cortex plays a crucial role in postural stability, and transcranial electrical stimulation of this region can modulate physical control responses. This study found that cathodal stimulation significantly decreased joint angular velocity in multiple directions, while there were no significant differences with transcranial random noise stimulation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xishuai Yang, Wei Zhang, Xueli Chang, Zuopeng Li, Runquan Du, Junhong Guo
Summary: This study aims to evaluate the efficacy of low-dose rituximab (RTX) in patients with muscle-specific kinase antibody positive myasthenia gravis (MuSK-MG). The results showed that low-dose RTX treatment led to significant improvements in clinical symptoms and quality of life for patients with MuSK-MG.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Jian Zhang, Shunyuan Guo, Rong Tao, Fan Wang, Yihong Xie, Huizi Wang, Lan Ding, Yuejian Shen, Xiaoli Zhou, Junli Feng, Qing Shen
Summary: This study established an Alzheimer's disease (AD) model of zebrafish induced by AlCl3 and found that marine-derived plasmalogens (Pls) could alleviate cognitive impairments of AD zebrafish by reversing athletic impairment and altering the expression levels of genes related to oxidative stress, ferroptosis, synaptic dysfunction, and apoptosis.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lu Li, Jiaqi Ren, Qi Fang, Liqiang Yu, Jintao Wang
Summary: ICU-AW is a common and severe neuromuscular complication in critically ill patients. Electrophysiological examination is essential for accurate diagnosis and early prediction of the disease. This study aimed to establish and validate an ICU-AW predictive model in SIRS patients, providing a practical tool for early clinical prediction.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Ahmad Alipour, Roghayeh Mohammadi
Summary: The present study aimed to investigate the separate and combined effects of anodal transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) and left dorsolateral prefrontal cortex (F3) regions on pain relief in patients with type-2 diabetes suffering from neuropathic pain (NP). The results showed that tDCS had the potential to induce pain relief in patients with type-2 diabetes suffering from NP. The mean perceived pain intensity in the posttest was lower in the M1 stimulation group than in the F3 stimulation group. However, more trials with larger sample sizes are necessary to define clinically relevant effects.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Eduardo J. Fusse, Franciele F. Scarante, Maria A. Vicente, Mariana M. Marrubia, Flavia Turcato, Davi S. Scomparin, Melissa A. Ribeiro, Maria J. Figueiredo, Tamires A. V. Brigante, Francisco S. Guimaraes, Alline C. Campos
Summary: Repeated exposure to psychosocial stress alters the endocannabinoid system and affects brain regions associated with emotional distress. Enhancing the effects of endocannabinoids through pharmacological inhibition induces an anti-stress behavioral effect, possibly mediated by the mTOR signaling pathway.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Giulia Agostoni, Luca Bischetti, Federica Repaci, Margherita Bechi, Marco Spangaro, Irene Ceccato, Elena Cavallini, Luca Fiorentino, Francesca Martini, Jacopo Sapienza, Mariachiara Buonocore, Michele Francesco D'Incalci, Federica Cocchi, Carmelo Guglielmino, Roberto Cavallaro, Marta Bosia, Valentina Bambini
Summary: This study found a general impairment in humor comprehension in individuals with schizophrenia, with mental jokes being more difficult for both patients and controls. Humor comprehension was closely associated with the patients' overall pragmatic and linguistic profile, while the association with Theory of Mind (ToM) was minimal. Another notable finding was the increased appreciation of humor in individuals with schizophrenia, who rated jokes as funnier than controls did, regardless of whether they were correctly or incorrectly completed. The funniness ratings were not predicted by any measure, suggesting a dimension of humor untied to cognition or psychopathology.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xiuping Gong, Qi Li, Yang Liu
Summary: This study demonstrates that Sev targets CREBBP to inhibit ALG13 transcription, leading to hippocampal damage and cognitive impairment.
NEUROSCIENCE LETTERS
(2024)