Hypocretin Receptor 2 Antagonism Dose-Dependently Reduces Escalated Heroin Self-Administration in Rats

Addiction as a stress surfeit disorder

(2013) George F. Koob et al.   NEUROPHARMACOLOGY

The NK1 Receptor Antagonist L822429 Reduces Heroin Reinforcement

(2013) Estelle Barbier et al.   NEUROPSYCHOPHARMACOLOGY

Extended Heroin Access Increases Heroin Choices Over a Potent Nondrug Alternative

(2013) Magalie Lenoir et al.   NEUROPSYCHOPHARMACOLOGY

Dynamic vaccine blocks relapse to compulsive intake of heroin

(2013) J. E. Schlosburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The differential effects of OX1R and OX2R selective antagonists on morphine conditioned place preference in naïve versus morphine-dependent mice

(2012) Mohammad Tabaeizadeh et al.   BEHAVIOURAL BRAIN RESEARCH

Intracerebroventricular injection of orexin-2 receptor antagonist promotes REM sleep

(2012) Basheer Ahamad Kummangal et al.   BEHAVIOURAL BRAIN RESEARCH

Orexin / hypocretin 1 receptor antagonist reduces heroin self-administration and cue-induced heroin seeking

(2012) Rachel J. Smith et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Corticosteroid-Dependent Plasticity Mediates Compulsive Alcohol Drinking in Rats

(2012) L. F. Vendruscolo et al.   JOURNAL OF NEUROSCIENCE

Hypothalamic Orexin-A Neurons Are Involved in the Response of the Brain Stress System to Morphine Withdrawal

(2012) M. Luisa Laorden et al.   PLoS One

Orexinergic innervation of the extended amygdala and basal ganglia in the rat

(2011) Oliver Schmitt et al.   Brain Structure & Function

Intra-ventral tegmental area or intracerebroventricular orexin-A increases the intra-cranial self-stimulation threshold via activation of the corticotropin-releasing factor system in rats

(2011) Toshimichi Hata et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Development of mechanical hypersensitivity in rats during heroin and ethanol dependence: Alleviation by CRF1 receptor antagonism

(2011) Scott Edwards et al.   NEUROPHARMACOLOGY

Escalation patterns of varying periods of heroin access

(2011) Leandro F. Vendruscolo et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Drug harms in the UK: a multicriteria decision analysis

(2010) David J Nutt et al.   LANCET

Corticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long- but not short-access rats

(2009) Thomas N. Greenwell et al.   ADDICTION BIOLOGY

Drug-induced and genetic alterations in stress-responsive systems: Implications for specific addictive diseases

(2009) Yan Zhou et al.   BRAIN RESEARCH

Blockade of Orexin-1 Receptors Attenuates Orexin-2 Receptor Antagonism-Induced Sleep Promotion in the Rat

(2009) C. Dugovic et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The α1 adrenergic receptor antagonist prazosin reduces heroin self-administration in rats with extended access to heroin administration

(2008) Thomas N. Greenwell et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR