Aging and gastrointestinal neuromuscular function: insights from within and outside the gut

mTOR's role in ageing: protein synthesis or autophagy?

(2016) Sarah L. Hands et al.   Aging-US

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

(2014) Anne Simonsen et al.   Autophagy

Epigenetic Control of Aging

(2010) Ursula Muñoz-Najar et al.   ANTIOXIDANTS & REDOX SIGNALING

NAD: A master regulator of transcription

(2010) Sanchari Ghosh et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging

(2010) Pankaj Kapahi et al.   Cell Metabolism

Growth hormone, insulin and aging: The benefits of endocrine defects

(2010) Andrzej Bartke   EXPERIMENTAL GERONTOLOGY

896 The Effect of Age on Regional and Whole Gut Transit Times in Healthy Adults

(2010) Richard J. Saad et al.   GASTROENTEROLOGY

Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated α-synuclein gene mutations precede central nervous system changes

(2010) Yien-Ming Kuo et al.   HUMAN MOLECULAR GENETICS

Signaling pathways in mitochondrial dysfunction and aging

(2010) Cristina Mammucari et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: Defective bricks build a defective house

(2010) Priyamvada Rai   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Changes in interstitial cells of cajal with age in the human stomach and colon

(2010) P. J. Gomez-Pinilla et al.   NEUROGASTROENTEROLOGY AND MOTILITY

A possibility of nutriceuticals as an anti-aging intervention: Activation of sirtuins by promoting mammalian NAD biosynthesis

(2010) Shin-ichiro Imai   PHARMACOLOGICAL RESEARCH

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

(2010) Patricia Spilman et al.   PLoS One

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Age-related changes in functional NANC innervation with VIP and substance P in the jejunum of Lewis rats

(2009) Michael S. Kasparek et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

SIRT1: Regulation of longevity via autophagy

(2009) Antero Salminen et al.   CELLULAR SIGNALLING

The clinical significance of gastrointestinal changes with aging

(2009) Asif Bhutto et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The second brain and Parkinson’s disease

(2009) Thibaud Lebouvier et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Alpha-synuclein immunopositive aggregates in the myenteric plexus of the aging Fischer 344 rat

(2009) Robert J. Phillips et al.   EXPERIMENTAL NEUROLOGY

Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease

(2009) James G. Greene et al.   EXPERIMENTAL NEUROLOGY

Chronic Constipation in the Elderly

(2009) Ernest P. Bouras et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Sialic acid feeding aged rats rejuvenates stimulated salivation and colon enteric neuron chemotypes

(2009) N. Sprenger et al.   GLYCOBIOLOGY

Proproliferative Functions ofDrosophilaSmall Mitochondrial Heat Shock Protein 22 in Human Cells

(2009) Renu Wadhwa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

5-HT4 Receptor-Mediated Neuroprotection and Neurogenesis in the Enteric Nervous System of Adult Mice

(2009) M.-T. Liu et al.   JOURNAL OF NEUROSCIENCE

Fall in density, but not number of myenteric neurons and circular muscle nerve fibres in guinea-pig colon with ageing

(2009) c. j. peck et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Effect of age on the enteric nervous system of the human colon

(2009) c. e. bernard et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Abnormal colonic motility in mice overexpressing human wild-type α-synuclein

(2009) Lixin Wang et al.   NEUROREPORT

Morphometric and quantitative study of the myenteric neurons of the stomach of malnourished aging rats

(2009) Fernando Carlos de Sousa et al.   NUTRITIONAL NEUROSCIENCE

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

The regulation of aging: does autophagy underlie longevity?

(2009) Tibor Vellai et al.   TRENDS IN CELL BIOLOGY

Autophagy genes and ageing

(2008) T Vellai   CELL DEATH AND DIFFERENTIATION

Deterioration of Muscle Function in the Human Esophagus with Age

(2008) Hans Gregersen et al.   DIGESTIVE DISEASES AND SCIENCES

Age and gender affect likely manometric diagnosis: Audit of a tertiary referral hospital clinical esophageal manometry service

(2008) Jane M Andrews et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Omega-3 polyunsaturated fatty acids increase the neurite outgrowth of rat sensory neurones throughout development and in aged animals

(2008) Lesley G. Robson et al.   NEUROBIOLOGY OF AGING

Enteric neurodegeneration in ageing

(2008) m. camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: Autonomic pathway implicated in Parkinson's disease?

(2008) R.J. Phillips et al.   NEUROSCIENCE

Age-related difference in nociceptive behavior between SAMP6 and SAMR1 strains

(2008) Kimie Niimi et al.   NEUROSCIENCE LETTERS