Article
Clinical Neurology
Benjamin M. Hampstead, Anthony Y. Stringer, Alexandru D. Iordan, Robert Ploutz-Snyder, K. Sathian
Summary: Cognitive training is a potential technique for treating cognitive impairment caused by neurological injury and disease. Different training methods have different mechanisms of action and engage distinct brain regions. Mnemonic strategy training (MST) showed superior effects in the short term and increased activation and functional connectivity in multiple brain regions.
ALZHEIMERS & DEMENTIA
(2023)
Review
Medicine, General & Internal
Gretchen O. Reynolds, Kim Willment, Seth A. Gale
Summary: This review focuses on the potential of mindfulness and cognitive training to improve cognition and mood in individuals with mild cognitive impairment, suggesting that these approaches are feasible and safe, with possible positive effects on cognition and mood, though some findings remain unclear or limited by methodological weaknesses.
AMERICAN JOURNAL OF MEDICINE
(2021)
Article
Rehabilitation
Pablo Cruz Gonzalez, Kenneth N. K. Fong, Ted Brown
Summary: The combination of tDCS with CT in older adults with MCI did not show superior effects on domain-specific cognitive outcomes compared to using sham tDCS with CT or CT alone. However, the combined method had larger effect sizes and improved processing speed of task-specific outcomes.
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE
(2021)
Article
Clinical Neurology
Tommy Kwan Hin Fong, Teris Cheung, Sze Ting Joanna Ngan, Kelvin Tong, Wai Yan Vivian Lui, Wai Chi Chan, Corine Sau Man Wong, Calvin Pak Wing Cheng
Summary: This study aimed to assess the effectiveness and tolerability of transcranial pulse stimulation (TPS) with neuro-navigation in older adults with mild neurocognitive disorder (NCD). The results showed a significant improvement in cognition of elderly with mild NCD after receiving TPS intervention. This study provides valuable information for the long-term effect of TPS in cognition in older adults.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
(2023)
Article
Psychiatry
G. Y. Roque Roque, J. Reyes-Lopez, J. Ricardo Garcell, M. Lopez Hidalgo, L. Aguilar Fabre, G. Trejo Cruz, S. Canizares Gomez, A. R. Calderon Moctezuma, F. Ortega Cruz, A. Ortiz Baron, N. A. Arias Garcia, M. Espino Cortes, H. Hernandez Montiel, J. Gonzalez Olvera
Summary: The study found that rTMS can significantly enhance Cognitive Stimulation in MCI patients, especially in the active group. This suggests that rTMS may help improve cognitive function in MCI patients.
PSYCHIATRY RESEARCH
(2021)
Review
Geriatrics & Gerontology
Gigi Chow, Javeil Ke En Gan, Janice Kuang Yeung Chan, Xi Vivien Wu, Piyanee Klainin-Yobas
Summary: The study found that psychosocial interventions were effective in improving memory for older adults with MCI, but had less impact on executive function, depression, and activities of daily living. Longer duration, more therapeutic sessions, and individual format interventions were associated with larger effect sizes compared to shorter durations, fewer sessions, and group formats. Strategies to enhance memory included behavior modification, memory training, visual imagery, storytelling, memory aids, journaling, and exercise.
AGING & MENTAL HEALTH
(2021)
Article
Psychology, Clinical
Johanne B. Tonga, Jurate Saltyte Benth, Espen A. Arnevik, Katja Werheid, Maria S. Korsnes, Ingun D. Ulstein
Summary: The study evaluated the CORDIAL program and found that this psychosocial intervention effectively reduced depressive symptoms in MCI and dementia patients, with effects persisting for up to 6 months post-intervention.
INTERNATIONAL PSYCHOGERIATRICS
(2021)
Review
Geriatrics & Gerontology
Xueyan Liu, Guangpeng Wang, Yingjuan Cao
Summary: This study aimed to assess the comparative effectiveness of nonpharmacological interventions on cognitive function in older adults with MCI. The results showed that mind-body exercise, dual-task exercise, and physical exercise may be effective in improving cognitive function. Acupressure + cognitive training was the most effective intervention. High-quality and large sample size RCT studies are needed to confirm these results.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Medicine, General & Internal
Violetta Kijowska, Ilona Baranska, Agata Stodolska, Katarzyna Szczerbinska
Summary: The study revealed that residents with cognitive impairment in long-term care facilities commonly participated in occupational therapy and medical rehabilitation, while the participation rates in cognitive therapy, physical activity group, psychological therapy, and enhancing activities of daily living were relatively low. There was significant diversity between facilities in the use of cognitive therapy, psychological therapy, and maintaining/enhancing activities of daily living.
POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ
(2021)
Review
Geriatrics & Gerontology
Isabel Gomez-Soria, Jorge Marin-Puyalto, Patricia Peralta-Marrupe, Eva Latorre, Estela Calatayud
Summary: This systematic review and meta-analysis examined the effects of multicomponent non-pharmacological interventions on older adults with mild cognitive impairment (MCI). The results showed that multicomponent non-pharmacological interventions could improve global cognition in older adults with MCI, especially when combined with physical interventions. However, no effects were observed on specific cognitive functions.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2022)
Review
Neurosciences
Themis Papaioannou, Alexandra Voinescu, Karin Petrini, Danae Stanton Fraser, Cosimo Tuena
Summary: The study found that VR training has moderate to large effects on cognitive abilities in patients with MCI and dementia, improving global cognition, attention, memory, and construction and motor performance in MCI patients, as well as global cognition, memory, and executive function in dementia patients. Moderators such as immersion and training type significantly influence the effects of VR training.
JOURNAL OF ALZHEIMERS DISEASE
(2022)
Article
Pediatrics
Helen Koechlin, Joe Kossowsky, Thanh Lan Lam, Johannes Barthel, Jens Gaab, Charles B. Berde, Guido Schwarzer, Klaus Linde, Karin Meissner, Cosima Locher
Summary: The study found that nonpharmacological interventions for pediatric migraine, including self-administered treatments, biofeedback, relaxation, psychological treatments, and psychological placebos, can effectively alleviate symptoms, although the effects should be interpreted carefully as some are based on small studies.
Review
Psychiatry
Rendong He, Jian Wei, Kexin Huang, Haiqi Yang, Yuanxin Chen, Zixin Liu, Jia Yong, Li Chen
Summary: Subthreshold depression is common and nonpharmacological interventions, especially psychotherapy and cognitive behavioral therapy, have been shown to be effective in improving symptoms in adults with Subthreshold depression.
PSYCHIATRY RESEARCH
(2022)
Review
Health Care Sciences & Services
Hai Mai Ba, Jiyun Kim
Summary: This review examined the effectiveness of physical and cognitive training on falls and cognitive function in community-dwelling elderly people with mild cognitive impairment. The findings suggested that PCT significantly impacted the cognitive function and physical activities of elderly people with MCI, particularly improving their balancing ability, gait speed, muscular strength, and executive functions.
Article
Health Care Sciences & Services
Ran Li, Jiawei Geng, Runze Yang, Yumeng Ge, Therese Hesketh
Summary: This systematic review suggests that computerized cognitive training (CCT) interventions could improve global cognitive function in patients with mild cognitive impairment (MCI), although the evidence is still limited. More comprehensive trials are needed to evaluate the impact of CCT on cognitive decline, especially in the longer term, and to determine whether CCT should be recommended for use in clinical practice.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Medicine, General & Internal
Eleni Poptsi, Despina Moraitou, Emmanouil Tsardoulias, Andreas L. Symeonidis, Vasileios Papaliagkas, Magdalini Tsolaki
Summary: The aim of this study was to extend the R4Alz battery by adding extra episodic memory tasks and cognitive control tasks, in order to improve its discriminant validity. The results showed that the tasks in the R4Alz-R battery were able to effectively discriminate between healthy adults, subjective cognitive decline, and mild cognitive impairment patients. Therefore, the R4Alz-R battery appears to be a useful tool for early diagnosis, as it can objectively evaluate the condition of minor neurocognitive diseases.
Review
Biology
Paschalis Devranis, Emilia Vassilopoulou, Vasileios Tsironis, Panagiotis Marios Sotiriadis, Michail Chourdakis, Michalis Aivaliotis, Magdalini Tsolaki
Summary: This study systematically reviewed the evidence of three dietary patterns, the Mediterranean diet, the ketogenic diet, and the MIND diet, for the prevention of cognitive decline. The analysis showed that all three dietary interventions could slow the rate of cognitive decline.
Article
Medicine, General & Internal
Vaitsa Giannouli, Magdalini Tsolaki
Summary: This study aims to examine specific deficits in metacognitive knowledge of self, task, and strategies in aMCI patients with a focus on mathematical cognition. Preliminary results showed significant differences in metacognitive knowledge between aMCI patients and healthy controls. Specific brain regions were identified as potential indicators for detecting metacognitive knowledge deficits in aMCI patients.
Article
Health Care Sciences & Services
Vaitsa Giannouli, Magdalini Tsolaki
Summary: This study aimed to investigate the influence of comorbid depression in mixed dementia patients on financial capacity. The results showed that financial capacity was significantly impaired in mixed dementia patients with coexisting depression, highlighting the importance of addressing this issue in neuropsychological assessments to prevent financial exploitation.
Article
Neurosciences
Bruno Mario Cesana, Eleni Poptsi, Magda Tsolaki, Sverre Bergh, Alfonso Ciccone, Emmanuel Cognat, Andrea Fabbo, Sara Fascendini, Giovanni B. Frisoni, Lutz Froelich, Maria Cristina Jori, Patrizia Mecocci, Paola Merlo, Oliver Peters, Carlo Alberto Defanti
Summary: This study conducted confirmatory and exploratory factor analyses on the Cohen-Mansfield Agitation Inventory (CMAI) to assess agitation in dementia patients. The results suggested that the current three-factor structure was not confirmed, and a new four-factor structure based on clinical criteria was proposed for a more accurate evaluation of symptoms.
Article
Neurosciences
Marianna Tsatali, Despina Moraitou, Evgenia Sakka Boza, Magdalini Tsolaki
Summary: This study aimed to investigate the multifactorial impact of the second lockdown measures and the one-year period after the second lockdown on the cognition, mood, and daily function of older adults with mild cognitive impairment (MCI) and Alzheimer's disease dementia (ADD) in Greece. The results showed that patients who participated in digital non-pharmacological interventions during the lockdown did not experience significant cognitive and functional deterioration, except for verbal memory as well as visual scanning and information processing.
Article
Health Care Sciences & Services
Aristi Alopoudi, Marina Makri, Batuhan Alisoglu, Abdullah Dogan, Antonino Imbesi, Mehmetcan Karakoyun, Alexis Lacapelle, Marco Aurelio Navarro Roux, Alexia Pissa, Magda Tsolaki
Summary: This paper describes the steps of developing and assessing a non-pharmacological intervention, specifically a Serious Game, with the goal of improving eight cognitive skills in adults with Intellectual Disabilities. Currently, there is a lack of a single tool that targets various cognitive skills as well as a broader spectrum of disorders.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2023)
Article
Psychology, Multidisciplinary
Styliani Olympia Tsormpatzoudi, Despina Moraitou, Vasileios Papaliagkas, Christos Pezirkianidis, Magda Tsolaki
Summary: This study explored the relationship between cognitive state, subjective wellbeing factors, negative psychological outcomes, and psychological resilience. The findings suggest that individuals with late MCI experience higher levels of negative psychological outcomes, poorer psychological resilience, and lower levels of subjective wellbeing compared to early MCI and healthy participants. These findings can be used to develop psychological interventions to enhance resilience and support brain health in older adults at risk of neurodegeneration.
BEHAVIORAL SCIENCES
(2023)
Article
Psychology, Multidisciplinary
Maria Sofologi, Evaggelia Foutsitzi, Aphrodite Papantoniou, Georgios Kougioumtzis, Harilaos Zaragas, Magdalini Tsolaki, Despina Moraitou, Georgia Papantoniou
Summary: This study investigated the relationships among high school teachers' tacit knowledge, professional development, and metacognitive knowledge related to teaching practices. The findings showed that there were associations between teachers' metacognitive knowledge about classroom management difficulties and the use of modern methods and technologies, as well as certain tacit knowledge strategies. Additionally, teachers' professional development, particularly their ability to interact in socially heterogeneous groups, was found to affect their tacit knowledge strategies.
JOURNAL OF INTELLIGENCE
(2023)
Article
Psychology, Multidisciplinary
Grigoria Bampa, Magdalini Tsolaki, Despina Moraitou, Panagiota Metallidou, Elvira Masoura, Maria Mintziviri, Konstantinos Paparis, Dorothea Tsourou, Georgia Papantoniou, Maria Sofologi, Vasileios Papaliagkas, Georgios Kougioumtzis, Efthymios Papatzikis
Summary: This study examined metacognitive abilities in individuals with amnestic mild cognitive impairment (aMCI) by using online measures. The findings showed that individuals with aMCI were aware of their cognitive limitations but still exhibited overconfidence. They also included more incorrect answers in their final scores compared to the healthy control group.
JOURNAL OF INTELLIGENCE
(2023)
Article
Psychology, Multidisciplinary
Foteini Aikaterini Pikouli, Despina Moraitou, Georgia Papantoniou, Maria Sofologi, Vasileios Papaliagkas, Georgios Kougioumtzis, Eleni Poptsi, Magdalini Tsolaki
Summary: This study aimed to investigate whether metacognitive strategy training could improve decision-making abilities in patients with amnestic mild cognitive impairment (MCI). The results showed that the experimental group, receiving the metacognitive strategy training, improved their ability to make decisions based on analytical thinking about economic and healthcare-related everyday decision-making situations. However, the ability to apply decision rules, which requires high cognitive effort, did not improve.
JOURNAL OF INTELLIGENCE
(2023)
Article
Clinical Neurology
Vaitsa Giannouli, Magdalini Tsolaki
Summary: This study investigates arithmetic errors in the financial context across neurocognitive disorders. The results show that different types of arithmetic errors occur in patients with Alzheimer's disease, mild cognitive impairment, and Parkinson's disease dementia. These errors may serve as indicators of specific brain pathologies.
NEUROLOGY INTERNATIONAL
(2023)
Review
Clinical Neurology
Eftychia Tziaka, Foteini Christidi, Dimitrios Tsiptsios, Anastasia Sousanidou, Stella Karatzetzou, Anna Tsiakiri, Triantafyllos K. Doskas, Konstantinos Tsamakis, Nikolaos Retzepis, Christos Konstantinidis, Christos Kokkotis, Aspasia Serdari, Nikolaos Aggelousis, Konstantinos Vadikolias
Summary: Stroke survivors have an increased risk of developing depression and cognitive decline. Biomarkers, such as leukoaraiosis (LA), can provide important information about the possibility of developing post-stroke depression (PSD) and post-stroke dementia (PSDem)/cognitive impairment. Identifying pre-existing white matter abnormalities can guide decision making in stroke settings.
NEUROLOGY INTERNATIONAL
(2023)
Article
Clinical Neurology
Triantafyllos K. Doskas, Foteini Christidi, Kanellos C. Spiliopoulos, Dimitrios Tsiptsios, George D. Vavougios, Anna Tsiakiri, Theofanis Vorvolakos, Christos Kokkotis, Ioannis Iliopoulos, Nikolaos Aggelousis, Konstantinos Vadikolias
Summary: Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system characterized by cognitive impairment, including social cognition deficits. Limited research is available on the impact of MS on social cognition, necessitating further investigation into factors influencing social cognition in PwMS.
NEUROLOGY INTERNATIONAL
(2023)
Review
Clinical Neurology
Aimilios Gkantzios, Vaia Karapepera, Dimitrios Tsiptsios, Eirini Liaptsi, Foteini Christidi, Elena Gkartzonika, Stella Karatzetzou, Christos Kokkotis, Mihail Kyrtsopoulos, Anna Tsiakiri, Paschalina Bebeletsi, Sofia Chaidemenou, Christos Koutsokostas, Konstantinos Tsamakis, Maria Baltzi, Dimitrios Mpalampanos, Nikolaos Aggelousis, Konstantinos Vadikolias
Summary: Given the expansion of life expectancy, the aging of the population, and the anticipated rise in the number of stroke survivors in Europe with severe neurological consequences in the coming decades, stroke is becoming the most prevalent cause of functional disability. This review investigates the relationship between thyroid hormone levels and acute stroke severity, mortality, and post-hospital prognosis. The findings suggest a potential correlation between low T3 syndrome, subclinical hypothyroidism, and poor stroke outcome, especially in certain age groups.
NEUROLOGY INTERNATIONAL
(2023)