Inhibition of intracerebral glioblastoma growth by targeting the insulin-like growth factor 1 receptor involves different context-dependent mechanisms

Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells

(2013) Annegret Kathagen et al.   ACTA NEUROPATHOLOGICA

Insulin growth factor receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with metastatic adrenocortical carcinoma

(2013) A Naing et al.   BRITISH JOURNAL OF CANCER

Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial

(2013) Gary K Schwartz et al.   LANCET ONCOLOGY

IGF-1R as an anti-cancer target--trials and tribulations

(2013) Helen X. Chen et al.   Chinese Journal of Cancer

Insulin-Like Growth Factors and Insulin: At the Crossroad Between Tumor Development and Longevity

(2012) R. Novosyadlyy et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARα -mediated inhibition of Glioma cell motility in vitro

(2012) Justyna Drukala et al.   Molecular Cancer

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

Concentrations of IGF-I and IGFBP-3 and Brain Tumor Risk in the European Prospective Investigation into Cancer and Nutrition

(2011) S. Rohrmann et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target

(2011) Alexander Schulte et al.   GLIA

Potent Inhibition of Angiogenesis by the IGF-1 Receptor-Targeting Antibody SCH717454 Is Reversed by IGF-2

(2011) H. K. Bid et al.   MOLECULAR CANCER THERAPEUTICS

Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma

(2011) S. Yin et al.   NEURO-ONCOLOGY

Regression of Recurrent Malignant Gliomas With Convection-Enhanced Delivery of Topotecan

(2011) Jeffrey N. Bruce et al.   NEUROSURGERY

Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma

(2010) S. Kunwar et al.   NEURO-ONCOLOGY

Inhibition of Glioblastoma Growth in a Highly Invasive Nude Mouse Model Can Be Achieved by Targeting Epidermal Growth Factor Receptor but not Vascular Endothelial Growth Factor Receptor-2

(2008) T. Martens et al.   CLINICAL CANCER RESEARCH