Alport syndrome from bench to bedside: the potential of current treatment beyond RAAS blockade and the horizon of future therapies

Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke

(2013) Lydia S. Murray et al.   HUMAN MOLECULAR GENETICS

Direct Transcriptional Reprogramming of Adult Cells to Embryonic Nephron Progenitors

(2013) C. E. Hendry et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Evidence for Activation of the Unfolded Protein Response in Collagen IV Nephropathies

(2013) M. Pieri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Laminin  2 Gene Missense Mutation Produces Endoplasmic Reticulum Stress in Podocytes

(2013) Y. M. Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Expert Guidelines for the Management of Alport Syndrome and Thin Basement Membrane Nephropathy

(2013) J. Savige et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Diagnosis of Alport syndrome—search for proteomic biomarkers in body fluids

(2013) Michael Pohl et al.   PEDIATRIC NEPHROLOGY

A Novel Source of Cultured Podocytes

(2013) Stefano Da Sacco et al.   PLoS One

Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells

(2013) Shin-Ichi Mae et al.   Nature Communications

Outcomes of Male Patients with Alport Syndrome Undergoing Renal Replacement Therapy

(2012) J. Temme et al.   Clinical Journal of the American Society of Nephrology

Injection of Amniotic Fluid Stem Cells Delays Progression of Renal Fibrosis

(2012) S. Sedrakyan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

An update on the pathomechanisms and future therapies of Alport syndrome

(2012) Damien Noone et al.   PEDIATRIC NEPHROLOGY

Clinical practice recommendations for the treatment of Alport syndrome: a statement of the Alport Syndrome Research Collaborative

(2012) Clifford E. Kashtan et al.   PEDIATRIC NEPHROLOGY

TGFβ-Stimulated MicroRNA-21 Utilizes PTEN to Orchestrate AKT/mTORC1 Signaling for Mesangial Cell Hypertrophy and Matrix Expansion

(2012) Nirmalya Dey et al.   PLoS One

The Directed Differentiation of Human iPS Cells into Kidney Podocytes

(2012) Bi Song et al.   PLoS One

MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

(2012) B. N. Chau et al.   Science Translational Medicine

Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy

(2011) Oliver Gross et al.   KIDNEY INTERNATIONAL

Mesenchymal stem cells in kidney inflammation and repair

(2011) ANDREA F. WISE et al.   NEPHROLOGY

Regenerative medicine of the kidney

(2010) Laura Perin et al.   ADVANCED DRUG DELIVERY REVIEWS

Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-α-mediated podocyte loss

(2010) Mi Ryu et al.   KIDNEY INTERNATIONAL

Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease

(2010) Oliver Gross et al.   MATRIX BIOLOGY

Macrophages in Renal Development, Injury, and Repair

(2010) Timothy M. Williams et al.   SEMINARS IN NEPHROLOGY

Stem Cell Therapies Benefit Alport Syndrome

(2009) V. LeBleu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cellular Origins of Type IV Collagen Networks in Developing Glomeruli

(2009) D. R. Abrahamson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY