Article
Biochemistry & Molecular Biology
Artem Zhukov, Alexandra Povaliaeva, Zaur Abilov, Elena Kovaleva, Liliya Usoltseva, Anna Eremkina, Vitaliy Ioutsi, Larisa Dzeranova, Ekaterina Pigarova, Liudmila Rozhinskaya, Natalia Mokrysheva
Summary: This study evaluated the extended spectrum of vitamin D metabolites in patients with HypoPT compared to healthy individuals. The results showed that patients with HypoPT achieved an adequate level of 25(OH)D-3 with standard doses of cholecalciferol, but they had supraphysiological levels of 1,25(OH)(2)D-3 and increased production of inactive metabolite. The abnormality of vitamin D metabolism does not seem to interfere with the achievement of hypoparathyroidism compensation.
Review
Nutrition & Dietetics
Mattia Perazzi, Enrico Gallina, Giulia Francesca Manfredi, Filippo Patrucco, Antonio Acquaviva, Donato Colangelo, Mario Pirisi, Mattia Bellan
Summary: This paper reviews the potential role of vitamin D in the pathogenesis and management of systemic sclerosis (SSc). Pre-clinical data suggest that vitamin D and its analogs may suppress fibrogenesis, while clinical data show a high prevalence of hypovitaminosis D and osteoporosis in SSc patients, but inconsistent findings regarding the association with clinical manifestations and phenotypes of SSc.
Review
Environmental Sciences
Jutti Levita, Gofarana Wilar, Ika Wahyuni, Lidya Cahyo Bawono, Tiara Ramadaini, Rohani Rohani, Ajeng Diantini
Summary: Intoxication of vitamin D is not commonly seen in pediatrics. This review provides insights into the clinical toxicology of vitamin D in pediatrics, including the mechanism, case reports, and management of vitamin D poisoning.
Article
Environmental Sciences
Alexandra E. Butler, Edwina Brennan, Daniel S. Drage, Thozhukat Sathyapalan, Stephen L. Atkin
Summary: This study examined the association of polychlorinated biphenyls (PCBs) with vitamin D in non-obese women. The results showed that certain PCBs were associated with vitamin D levels, but these associations could be explained by body mass index (BMI). Therefore, the deleterious effects of PCB accumulation are not mediated by effects on vitamin D levels.
ENVIRONMENTAL RESEARCH
(2023)
Article
Nutrition & Dietetics
Mario Flores-Aldana, Marta Rivera-Pasquel, Armando Garcia-Guerra, Jesus Giovanni Perez-Cortes, Juan E. Barcena-Echegollen
Summary: This study aimed to assess the effect of vitamin D supplementation at different doses on serum 25(OH)D concentrations in preschool children. After three months, there was a significant increase in serum concentrations of 25(OH)D and a decrease in the prevalence of vitamin D deficiency. No adverse effects were observed.
Article
Nutrition & Dietetics
Verena Theiler-Schwetz, Christian Trummer, Martin R. Grubler, Martin H. Keppel, Armin Zittermann, Andreas Tomaschitz, Spyridon N. Karras, Winfried Marz, Stefan Pilz, Stephanie Gangler
Summary: This post hoc analysis investigated the effects of vitamin D on blood pressure and found that vitamin D supplementation did not have an antihypertensive effect in individuals with vitamin D deficiency. However, there was a significant association between achieved 25(OH)D concentrations and blood pressure.
Article
Nutrition & Dietetics
Souzana E. Xyda, Kalliopi Kotsa, Argyrios Doumas, Emmanouil Papanastasiou, Alexandros A. Garyfallos, George Samoutis
Summary: The prevalence of vitamin D deficiency is paradoxically high in both Mediterranean countries, Greece and Cyprus, despite ample sunlight in the region. Only the month and gender were significantly associated with vitamin D levels.
Article
Biochemistry & Molecular Biology
Edwina Brennan, Alexandra E. Butler, Manjula Nandakumar, Daniel S. Drage, Thozhukat Sathyapalan, Stephen L. Atkin
Summary: This study examined the association between organochlorine pesticides (OCPs) and vitamin D deficiency. The results showed a correlation between OCPs and vitamin D-3, as well as the active metabolite 1,25-dihydrovitamin D-3. The study also suggested that OCP effects may be enhanced in cases of vitamin D deficiency.
Article
Nutrition & Dietetics
Suma Uday, Sunia Naseem, Jamie Large, Russell Denmeade, Philippa Goddard, Mary Anne Preece, Rachel Dunn, William Fraser, Jonathan C. Y. Tang, Wolfgang Hoegler
Summary: This study aimed to evaluate the prevalence of Vitamin D deficiency among newborns in an ethnically diverse UK population. Results showed that almost 70% of newborns and 85% of winter-born babies had Vitamin D concentrations below 50 nmol/L, highlighting the urgent need for a review of antenatal and infant Vitamin D supplementation programs.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Alexandra Povaliaeva, Viktor Bogdanov, Ekaterina Pigarova, Artem Zhukov, Larisa Dzeranova, Zhanna Belaya, Liudmila Rozhinskaya, Galina Mel'nichenko, Natalia Mokrysheva
Summary: The study found that patients with Cushing's disease exhibit differences in vitamin D metabolism compared to healthy individuals, such as consistently higher 25(OH)D-3/24,25(OH)(2)D-3 ratios. Additionally, patients with CD have lower levels of free 25(OH)D compared to the control group, and a significant correlation between baseline free 25(OH)D levels and cortisol levels was observed.
Review
Nutrition & Dietetics
Rakesh Balachandar, Raghu Pullakhandam, Bharati Kulkarni, Harshpal Singh Sachdev
Summary: This study found that cholecalciferol was more effective than ergocalciferol in improving vitamin D status and regulating PTH levels, regardless of participant demographics, dosage, and vehicle of supplementation.
Article
Endocrinology & Metabolism
Jose Luis Perez-Castrillon, Antonio Duenas-Laita, Carlos Gomez-Alonso, Esteban Jodar, Javier del Pino-Montes, Maria Luisa Brandi, Fernando Cereto Castro, Jose Manuel Quesada-Gomez, Laura Gallego Lopez, Jose Manuel Olmos Martinez, Maria Rosa Alhambra Exposito, Bernat Galarraga, Jesus Gonzalez-Macias, Jose Luis Neyro, Roger Bouillon, Gonzalo Hernandez-Herrero, Nieves Fernandez-Hernando, Sandra P. Chinchilla
Summary: This report presents the results of a 1-year clinical trial comparing the efficacy and safety of monthly calcifediol and cholecalciferol in postmenopausal women with vitamin D deficiency. The study found that monthly calcifediol is an effective and safe treatment, maintaining stable vitamin D levels.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Review
Chemistry, Applied
Suene V. S. Souza, Nuno Borges, Elsa F. Vieira
Summary: This review summarizes theoretical models of fortification, stability, bioaccessibility, and bioavailability studies of vitamin D-fortified breads, as well as clinical effects. Results suggest that vitamin D-fortified bread is a promising fortification strategy, leading to increased serum concentrations of 25(OH)D and decreased parathyroid hormone, but further studies are needed to elucidate its effects in the prevention/treatment of vitamin D deficiency.
Review
Nutrition & Dietetics
Pawel Pludowski, Istvan Takacs, Mihail Boyanov, Zhanna Belaya, Camelia C. Diaconu, Tatiana Mokhort, Nadiia Zherdova, Ingvars Rasa, Juraj Payer, Stefan Pilz
Summary: Vitamin D deficiency is a global issue with diverse guidelines for diagnosis and treatment. Screening for deficiency is not recommended for the general population, but testing is suggested for certain risk groups. Daily supplementation of 800 to 2000 IU of vitamin D is recommended for adults.
Article
Endocrinology & Metabolism
Jing Cheng, Jianhua Zhai, Weilong Zhong, Jingwen Zhao, Lu Zhou, Bangmao Wang
Summary: The study suggests that Lactobacillus rhamnosus GG culture supernatant (LCS) can promote intestinal absorption of cholecalciferol by affecting protein levels of VD transporters, thus improving the levels of 25OHD(3) in senile osteoporosis (SOP).
CALCIFIED TISSUE INTERNATIONAL
(2022)
Article
Urology & Nephrology
Guillaume Chazot, Manolie Mehdi, Christie Lorriaux, Patrik Deleaval, Brice Mayor, Guillaume Jean, Charles Chazot, Sylvain Lechevallier, Oriane Moncel, Cyril Vo-Van, Jean-Marc Hurot
NEPHROLOGIE & THERAPEUTIQUE
(2018)
Article
Multidisciplinary Sciences
Guillaume Jean, Marie Helene Lafage-Proust, Jean Claude Souberbielle, Sylvain Lechevallier, Patrik Deleaval, Christie Lorriaux, Jean Marc Hurot, Brice Mayor, Manolie Mehdi, Charles Chazot
Article
Transplantation
Cedric Villain, Rene Ecochard, Jean-Louis Bouchet, Eric Daugas, Tilman B. Drueke, Thierry Hannedouche, Guillaume Jean, Gerard London, Hubert Roth, Denis Fouque
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2019)
Article
Hematology
Charles Chazot, Guillaume Jean
BLOOD PURIFICATION
(2019)
Article
Urology & Nephrology
Charles Chazot, Baya Fadel, Mimi Kareche, Olivier Puyoo, Guillaume Jean
NEPHROLOGIE & THERAPEUTIQUE
(2019)
Letter
Hematology
Charles Chazot, Guillaume Jean
BLOOD PURIFICATION
(2019)
Article
Urology & Nephrology
Guillaume Jean, Charles Chazot
NEPHROLOGIE & THERAPEUTIQUE
(2019)
Article
Transplantation
Charles Chazot, Sebastien Deleuze, Baya Fadel, Hadia Hebibi, Guillaume Jean, Martial Levannier, Olivier Puyoo, David Attaf, Stefano Stuard, Bernard Canaud
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2019)
Review
Medical Laboratory Technology
Anne-Sophie Bargnoux, Yann Barguil, Eric Zaoui, Guillaume Jean, Jean-Paul Cristol
ANNALES DE BIOLOGIE CLINIQUE
(2019)
Review
Urology & Nephrology
Guillaume Jean, Patrik Deleaval, Charles Chazot
Summary: The use of natriuretic peptides for acute cardiac failure diagnosis is common among cardiologists and emergency-wards physicians, but controversial in chronic kidney disease patients. Clinical practices in interpreting natriuretic peptides, particularly B-type, play a crucial role in monitoring fluid variations and cardiac disease status in dialysis patients. Longitudinal follow-up of B-type natriuretic peptide is essential for early detection and treatment of extracellular fluid variations and cardiac disease status, which are associated with hard outcomes.
NEPHROLOGIE & THERAPEUTIQUE
(2021)
Article
Urology & Nephrology
Cecile Couchoud, Florian Bayer, Carole Ayav, Clemence Bechade, Philippe Brunet, Francois Chantrel, Luc Frimat, Roula Galland, Maryvonne Hourmant, Emmanuelle Laurain, Thierry Lobbedez, Lucile Mercadal, Olivier Moranne
KIDNEY INTERNATIONAL
(2020)
Article
Medicine, Research & Experimental
Stanislas Bataille, Nathalie Pedinielli, Elisa Carreno, Mathilde Prezelin-Reydit, Philippe Chauveau, Guillaume Jean, Thomas Robert, Mickael Bobot, Guillaume Seret, Elisabeth Jouve, Frederic Lavainne, Marianne Serveaux, Laurence Vrigneaud, Stephanie Gentile
Summary: The study aims to investigate whether cholecalciferol supplementation can improve muscle strength in hemodialysis patients with low 25OHD levels. The main objective is to analyze the effect of oral cholecalciferol supplementation on muscle strength in these patients, while secondary objectives include analyzing 25OHD plasma levels after supplementation and factors associated with 25OHD decline speed, as well as assessing the impact on patient autonomy, frailty risk, and quality of life.
Article
Urology & Nephrology
Charles Chazot, Claire de Kerautem, Hadia Hebibi, Marie-Odile Heimig, Lise Weis, Arsene Attroun, Guillaume Jean, Philippe Rousseau, Samah Saibi, Sabine Flangakis, Benjamin Raulet, Pascal Maufroy, Jean-Louis Brunet, Sophie Lachaux-Vaillier, Sophie Privat, Solene Pourrat, Bernard Thuillet, Francesco Rabasco, Maxime Theodose, Martial Levannier, Kais Tahiri
Summary: During the COVID crisis, NephroCare implemented necessary measures to ensure the safety of dialysis patients, which were modified during the three waves. These measures effectively controlled the dialysis parameters and PCR results of asymptomatic patients, with a contamination rate below the national average. In the third wave, vaccination was implemented, resulting in a decrease in COVID cases.
NEPHROLOGIE & THERAPEUTIQUE
(2022)
Article
Hematology
Charles Chazot, Lise Weis, Hadia Hebibi, Guillaume Jean, Sebastien Deleuze, Martial Levannier, David Attaf, Stefano Stuard
Summary: During the COVID-19 crisis, the Paris region was most affected, with 73% of all contaminations in French NC units occurring there. Dialysis frequency, processed blood volume, and other indicators decreased significantly in the Paris region but remained stable in other regions. The increase in 3-month weight loss among HD patients may be attributed to the cancellation of intradialytic snacks, affecting more malnourished patients or those with lower interdialytic weight gain.
BLOOD PURIFICATION
(2022)
Article
Urology & Nephrology
Denis Fouque, Hubert Roth, Bernadette Darne, Jean-Louis Bouchet, Eric Daugas, Tilman B. Drueke, Thierry Hannedouche, Guillaume Jean, Gerard M. London
CLINICAL KIDNEY JOURNAL
(2018)