Modulation of GPCRs by monovalent cations and anions

Neuroprotective Effects of Lithium: Implications for the Treatment of Alzheimer’s Disease and Related Neurodegenerative Disorders

(2014) O. V. Forlenza et al.   ACS Chemical Neuroscience

Mechanistic Insights into the Allosteric Modulation of Opioid Receptors by Sodium Ions

(2014) Yi Shang et al.   BIOCHEMISTRY

Molecular control of δ-opioid receptor signalling

(2014) Gustavo Fenalti et al.   NATURE

High- and low-affinity sites for sodium in δ-OR-Gi1α (Cys351-Ile351) fusion protein stably expressed in HEK293 cells; functional significance and correlation with biophysical state of plasma membrane

(2014) Miroslava Vošahlíková et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The 2.1 Å Resolution Structure of Cyanopindolol-Bound β1-Adrenoceptor Identifies an Intramembrane Na+ Ion that Stabilises the Ligand-Free Receptor

(2014) Jennifer L. Miller-Gallacher et al.   PLoS One

Dual regulation of G proteins and the G-protein–activated K+channels by lithium

(2014) Isabella Farhy Tselnicker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allosteric sodium in class A GPCR signaling

(2014) Vsevolod Katritch et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Role of Water and Sodium Ions in the Activation of the μ-Opioid Receptor

(2013) Shuguang Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

White matter alterations in bipolar disorder: potential for drug discovery and development

(2013) Emeline Marlinge et al.   BIPOLAR DISORDERS

Cation-Specific Effects on Enzymatic Catalysis Driven by Interactions at the Tunnel Mouth

(2013) Veronika Štěpánková et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Cl− channels in smooth muscle cells

(2013) Simon Bulley et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Temporal Trend in Hospitalizations for Acute Diabetic Complications: A Nationwide Study, Italy, 2001–2010

(2013) Flavia Lombardo et al.   PLoS One

Hofmeister Phenomena: An Update on Ion Specificity in Biology

(2012) Pierandrea Lo Nostro et al.   CHEMICAL REVIEWS

A systematic review of the safety of potassium bromide in dogs

(2012) Hope E. Baird-Heinz et al.   JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Molecular Mechanisms of Ion-Specific Effects on Proteins

(2012) Kelvin B. Rembert et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

(2012) W. Liu et al.   SCIENCE

A Study of the Hydration of the Alkali Metal Ions in Aqueous Solution

(2011) Johan Mähler et al.   INORGANIC CHEMISTRY

Ions and the Protein Surface Revisited: Extensive Molecular Dynamics Simulations and Analysis of Protein Structures in Alkali-Chloride Solutions

(2011) Ran Friedman   JOURNAL OF PHYSICAL CHEMISTRY B

Functional reconstitution of human neuropeptide Y (NPY) Y2and Y4receptors in Sf9 insect cells

(2011) Nathalie Pop et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Structure of the human histamine H1 receptor complex with doxepin

(2011) Tatsuro Shimamura et al.   NATURE

Role of the second and third extracellular loops of the histamine H4 receptor in receptor activation

(2011) Irena Brunskole et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The osmopressor response to water drinking

(2010) Marcus May et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Differential Requirements of Sodium for Coupling of Cannabinoid Receptors to Adenylyl Cyclase in Rat Brain Membranes

(2010) Mary A. Pacheco et al.   JOURNAL OF NEUROCHEMISTRY

Modulation of histamine H3 receptor function by monovalent ions

(2010) David Schnell et al.   NEUROSCIENCE LETTERS

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

(2010) E. Y. T. Chien et al.   SCIENCE

High Constitutive Activity and a G-Protein-Independent High-Affinity State of the Human Histamine H4-Receptor†

(2009) Erich H. Schneider et al.   BIOCHEMISTRY

Hofmeister effects on activity and stability of alkaline phosphatase

(2009) Zhen Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Lithium: Updated Human Knowledge Using an Evidence-Based Approach

(2009) Etienne Marc Grandjean et al.   CNS DRUGS

Akt/GSK3 Signaling in the Action of Psychotropic Drugs

(2008) Jean-Martin Beaulieu et al.   Annual Review of Pharmacology and Toxicology

Ligand Selectivity of D2 Dopamine Receptors Is Modulated by Changes in Local Dynamics Produced by Sodium Binding

(2008) S. S. Ericksen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Determination of Alkali and Halide Monovalent Ion Parameters for Use in Explicitly Solvated Biomolecular Simulations

(2008) In Suk Joung et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Functional reconstitution of the human chemokine receptor CXCR4 with Gi/Go-proteins in Sf9 insect cells

(2008) Patrick Kleemann et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Differential coupling of the human cannabinoid receptors hCB1R and hCB2R to the G-protein Gαi2β1γ2

(2008) Kathrin Nickl et al.   NEUROSCIENCE LETTERS