Mechanisms of genetic instability caused by (CGG)n repeats in an experimental mammalian system

Nanopore sequencing of complex genomic rearrangements in yeast reveals mechanisms of repeat-mediated double-strand break repair

(2017) Ryan J. McGinty et al.   GENOME RESEARCH

Fragile X-Associated Diminished Ovarian Reserve and Primary Ovarian Insufficiency from Molecular Mechanisms to Clinical Manifestations

(2017) Limor Man et al.   Frontiers in Molecular Neuroscience

Alternative lengthening of human telomeres is a conservative DNA replication process with features of break‐induced replication

(2016) Fani‐Marlen Roumelioti et al.   EMBO REPORTS

Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks

(2016) Sotirios K. Sotiriou et al.   MOLECULAR CELL

Mechanisms underlying structural variant formation in genomic disorders

(2016) Claudia M. B. Carvalho et al.   NATURE REVIEWS GENETICS

The role of break-induced replication in large-scale expansions of (CAG) n /(CTG) n repeats

(2016) Jane C Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The role of break-induced replication in large-scale expansions of (CAG) n /(CTG) n repeats

(2016) Jane C Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich’s Ataxia Cells

(2016) Jeannine Gerhardt et al.   Cell Reports

The hidden side of unstable DNA repeats: Mutagenesis at a distance

(2015) Kartik A. Shah et al.   DNA REPAIR

Impact of alternative DNA structures on DNA damage, DNA repair, and genetic instability

(2014) Guliang Wang et al.   DNA REPAIR

A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function

(2014) Artem V. Kononenko et al.   NUCLEIC ACIDS RESEARCH

Break-Induced Replication Is a Source of Mutation Clusters Underlying Kataegis

(2014) Cynthia J. Sakofsky et al.   Cell Reports

RTEL1 Inhibits Trinucleotide Repeat Expansions and Fragility

(2014) Aisling Frizzell et al.   Cell Reports

Break-induced replication: functions and molecular mechanism

(2013) Anna Malkova et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The balancing act of DNA repeat expansions

(2013) Jane C Kim et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Gender and Cell-Type-Specific Effects of the Transcription-Coupled Repair Protein, ERCC6/CSB, on Repeat Expansion in a Mouse Model of the Fragile X-Related Disorders

(2013) Xiao-Nan Zhao et al.   HUMAN MUTATION

The DNA Replication Program Is Altered at the FMR1 Locus in Fragile X Embryonic Stem Cells

(2013) Jeannine Gerhardt et al.   MOLECULAR CELL

Friedreich's ataxia–associated GAA repeats induce replication-fork reversal and unusual molecular junctions

(2013) Cindy Follonier et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells

(2013) Lorenzo Costantino et al.   SCIENCE

Role of Mismatch Repair Enzymes in GAA·TTC Triplet-repeat Expansion in Friedreich Ataxia Induced Pluripotent Stem Cells

(2012) Jintang Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Mismatch Repair Complex MutSβ Promotes GAA·TTC Repeat Expansion in Human Cells

(2012) Anasheh Halabi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Werner Syndrome Protein Promotes CAG/CTG Repeat Stability by Resolving Large (CAG)n/(CTG)nHairpins

(2012) Nelson L. S. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered Replication in Human Cells Promotes DMPK (CTG)n {middle dot} (CAG)n Repeat Instability

(2012) G. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model

(2012) Vahid Ezzatizadeh et al.   NEUROBIOLOGY OF DISEASE

Effects of Friedreich's ataxia GAA repeats on DNA replication in mammalian cells

(2012) Gurangad S. Chandok et al.   NUCLEIC ACIDS RESEARCH

tRNA genes protect a reporter gene from epigenetic silencing in mouse cells

(2011) Thomas Ebersole et al.   CELL CYCLE

FMR1 premutation and full mutation molecular mechanisms related to autism

(2011) Randi Hagerman et al.   Journal of Neurodevelopmental Disorders

Friedreich's Ataxia Induced Pluripotent Stem Cells Model Intergenerational GAA⋅TTC Triplet Repeat Instability

(2010) Sherman Ku et al.   Cell Stem Cell

Huntington's and myotonic dystrophy hESCs: down-regulated trinucleotide repeat instability and mismatch repair machinery expression upon differentiation

(2010) Anna Seriola et al.   HUMAN MOLECULAR GENETICS

Bidirectional transcription stimulates expansion and contraction of expanded (CTG)•(CAG) repeats

(2010) Masayuki Nakamori et al.   HUMAN MOLECULAR GENETICS

Replication-dependent instability at (CTG)•(CAG) repeat hairpins in human cells

(2010) Guoqi Liu et al.   Nature Chemical Biology

Mechanisms of trinucleotide repeat instability during human development

(2010) Cynthia T. McMurray   NATURE REVIEWS GENETICS

Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing

(2009) J.-H. Kim et al.   GENOME RESEARCH

Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility

(2009) Irina Voineagu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

R loops stimulate genetic instability of CTG{middle dot}CAG repeats

(2009) Y. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA