Role of Mismatch Repair Enzymes in GAA·TTC Triplet-repeat Expansion in Friedreich Ataxia Induced Pluripotent Stem Cells

The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model

(2012) Vahid Ezzatizadeh et al.   NEUROBIOLOGY OF DISEASE

Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome

(2011) Steven D. Sheridan et al.   PLoS One

Friedreich's Ataxia Induced Pluripotent Stem Cells Model Intergenerational GAA⋅TTC Triplet Repeat Instability

(2010) Sherman Ku et al.   Cell Stem Cell

Huntington's and myotonic dystrophy hESCs: down-regulated trinucleotide repeat instability and mismatch repair machinery expression upon differentiation

(2010) Anna Seriola et al.   HUMAN MOLECULAR GENETICS

FGF-2 modulates Wnt signaling in undifferentiated hESC and iPS cells through activated PI3-K/GSK3β signaling

(2010) Vanessa M.Y. Ding et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mechanisms of trinucleotide repeat instability during human development

(2010) Cynthia T. McMurray   NATURE REVIEWS GENETICS

Role of transcript and interplay between transcription and replication in triplet-repeat instability in mammalian cells

(2010) P. M. Rindler et al.   NUCLEIC ACIDS RESEARCH

Robust Enhancement of Neural Differentiation from Human ES and iPS Cells Regardless of their Innate Difference in Differentiation Propensity

(2010) Dae-Sung Kim et al.   Stem Cell Reviews and Reports

Generation of Induced Pluripotent Stem Cell Lines from Friedreich Ataxia Patients

(2010) Jun Liu et al.   Stem Cell Reviews and Reports

High-Efficiency Induction of Neural Conversion in Human ESCs and Human Induced Pluripotent Stem Cells with a Single Chemical Inhibitor of Transforming Growth Factor Beta Superfamily Receptors

(2010) Jiaxi Zhou et al.   STEM CELLS

Large-Scale Expansions of Friedreich's Ataxia GAA Repeats in Yeast

(2009) Alexander A. Shishkin et al.   MOLECULAR CELL

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

R loops stimulate genetic instability of CTG{middle dot}CAG repeats

(2009) Y. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progressive GAA·TTC Repeat Expansion in Human Cell Lines

(2009) Scott Ditch et al.   PLoS Genetics

Detection of triplet repeat sequences in the double-stranded DNA using pyrene-functionalized pyrrole–imidazole polyamides with rigid linkers

(2008) Jun Fujimoto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Features of trinucleotide repeat instability in vivo

(2008) Irina V Kovtun et al.   CELL RESEARCH

Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair

(2008) Hyun-Min Kim et al.   EMBO JOURNAL

Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes

(2008) Ella Dragileva et al.   NEUROBIOLOGY OF DISEASE