DNA methylation and miRNA—key roles in systemic autoimmunity

Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

(2013) Patrick Coit et al.   JOURNAL OF AUTOIMMUNITY

Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression

(2013) Lorenzo de la Rica et al.   JOURNAL OF AUTOIMMUNITY

The Catalytic Subunit of Protein Phosphatase 2A (PP2Ac) Promotes DNA Hypomethylation by Suppressing the Phosphorylated Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Kinase (MEK)/Phosphorylated ERK/DNMT1 Protein Pathway in T-cells from Controls and Systemic Lupus Erythematosus Patients

(2013) Katsue Sunahori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA methylome signature in rheumatoid arthritis

(2012) Kazuhisa Nakano et al.   ANNALS OF THE RHEUMATIC DISEASES

Protein kinase Cδ oxidation contributes to ERK inactivation in lupus T cells

(2012) Gabriela J. Gorelik et al.   ARTHRITIS AND RHEUMATISM

Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients

(2008) A H Sawalha et al.   GENES AND IMMUNITY