Nitrogen metabolism in Mycobacterium tuberculosis physiology and virulence

Survival of mycobacteria depends on proteasome-mediated amino acid recycling under nutrient limitation

(2014) Y. Elharar et al.   EMBO JOURNAL

Amino acid capture and utilization within theMycobacterium tuberculosisphagosome

(2014) Alexandre Gouzy et al.   Future Microbiology

Mycobacterium tuberculosis Exploits Asparagine to Assimilate Nitrogen and Resist Acid Stress during Infection

(2014) Alexandre Gouzy et al.   PLoS Pathogens

Genome wide analysis of the complete GlnR nitrogen-response regulon in Mycobacterium smegmatis

(2013) Victoria A Jenkins et al.   BMC GENOMICS

Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

(2013) Yanjia J. Zhang et al.   CELL

Feast or famine: the host-pathogen battle over amino acids

(2013) Yanjia J. Zhang et al.   CELLULAR MICROBIOLOGY

13C-Flux Spectral Analysis of Host-Pathogen Metabolism Reveals a Mixed Diet for Intracellular Mycobacterium tuberculosis

(2013) Dany J.V. Beste et al.   CHEMISTRY & BIOLOGY

Autophagy as an immune effector against tuberculosis

(2013) Steven B Bradfute et al.   CURRENT OPINION IN MICROBIOLOGY

Reversible Lipid Accumulation and Associated Division Arrest of Mycobacterium avium in Lipoprotein-Induced Foamy Macrophages May Resemble Key Events during Latency and Reactivation of Tuberculosis

(2013) Irène Caire-Brändli et al.   INFECTION AND IMMUNITY

The Intracellular Environment of Human Macrophages That Produce Nitric Oxide Promotes Growth of Mycobacteria

(2013) Joo-Yong Jung et al.   INFECTION AND IMMUNITY

WHO's 2013 global report on tuberculosis: successes, threats, and opportunities

(2013) Alimuddin Zumla et al.   LANCET

Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate

(2013) Alexandre Gouzy et al.   Nature Chemical Biology

Systems-Based Approaches to Probing Metabolic Variation within the Mycobacterium tuberculosis Complex

(2013) Emma K. Lofthouse et al.   PLoS One

The Role of Glutamine Oxoglutarate Aminotransferase and Glutamate Dehydrogenase in Nitrogen Metabolism in Mycobacterium bovis BCG

(2013) Albertus J. Viljoen et al.   PLoS One

Nitrite produced by Mycobacterium tuberculosis in human macrophages in physiologic oxygen impacts bacterial ATP consumption and gene expression

(2013) A. Cunningham-Bussel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenylylation of mycobacterial Glnk (PII) protein is induced by nitrogen limitation

(2013) Kerstin J. Williams et al.   TUBERCULOSIS

Francisella tularensis Harvests Nutrients Derived via ATG5-Independent Autophagy to Support Intracellular Growth

(2013) Shaun Steele et al.   PLoS Pathogens

Glucose Phosphorylation Is Required for Mycobacterium tuberculosis Persistence in Mice

(2013) Joeli Marrero et al.   PLoS Pathogens

Mycobacterium tuberculosis-Driven Targeted Recalibration of Macrophage Lipid Homeostasis Promotes the Foamy Phenotype

(2012) Varshneya Singh et al.   Cell Host & Microbe

Sustained Generation of Nitric Oxide and Control of Mycobacterial Infection Requires Argininosuccinate Synthase 1

(2012) Joseph E. Qualls et al.   Cell Host & Microbe

Francisella tularensisregulates the expression of the amino acid transporter SLC1A5 in infected THP-1 human monocytes

(2012) Monique Barel et al.   CELLULAR MICROBIOLOGY

Urease Activity Represents an Alternative Pathway for Mycobacterium tuberculosis Nitrogen Metabolism

(2012) Wenwei Lin et al.   INFECTION AND IMMUNITY

Quantitative Proteomics Reveals That Only a Subset of the Endoplasmic Reticulum Contributes to the Phagosome

(2012) François-Xavier Campbell-Valois et al.   MOLECULAR & CELLULAR PROTEOMICS

Mutational Analysis of the Respiratory Nitrate Transporter NarK2 of Mycobacterium tuberculosis

(2012) Michelle M. Giffin et al.   PLoS One

Toward a Systemic Understanding of Listeria monocytogenes Metabolism during Infection

(2012) Thilo M. Fuchs et al.   Frontiers in Microbiology

Tryptophan Prototrophy Contributes to Francisella tularensis Evasion of Gamma Interferon-Mediated Host Defense

(2011) Ping Chu et al.   INFECTION AND IMMUNITY

Uptake of Sulfate but Not Phosphate by Mycobacterium tuberculosis Is Slower than That for Mycobacterium smegmatis

(2011) H. Song et al.   JOURNAL OF BACTERIOLOGY

Metabolic Profiling of Lung Granuloma inMycobacterium tuberculosisInfected Guinea Pigs: Ex vivo1H Magic Angle Spinning NMR Studies

(2011) B. S. Somashekar et al.   JOURNAL OF PROTEOME RESEARCH

1H NMR-based Metabolomic Profiling in Mice Infected withMycobacterium tuberculosis

(2011) Ji-Hyun Shin et al.   JOURNAL OF PROTEOME RESEARCH

Nitrate reduction pathways in mycobacteria and their implications during latency

(2011) A. Khan et al.   MICROBIOLOGY-SGM

Host Proteasomal Degradation Generates Amino Acids Essential for Intracellular Bacterial Growth

(2011) C. T. D. Price et al.   SCIENCE

Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier

(2011) Kyu Y. Rhee et al.   TRENDS IN MICROBIOLOGY

13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation

(2011) Dany J. V. Beste et al.   PLoS Pathogens

Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages

(2011) Jaiyanth Daniel et al.   PLoS Pathogens

Carbon metabolism of intracellular bacterial pathogens and possible links to virulence

(2010) Wolfgang Eisenreich et al.   NATURE REVIEWS MICROBIOLOGY

Cationic Amino Acid Transporters and Salmonella Typhimurium ArgT Collectively Regulate Arginine Availability towards Intracellular Salmonella Growth

(2010) Priyanka Das et al.   PLoS One

Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein

(2010) Nishant D. Shetty et al.   PROTEIN SCIENCE

The Mycobacterium tuberculosis Proteasome Active Site Threonine Is Essential for Persistence Yet Dispensable for Replication and Resistance to Nitric Oxide

(2010) Sheetal Gandotra et al.   PLoS Pathogens

Mycobacterial survival strategies in the phagosome: defence against host stresses

(2009) Sabine Ehrt et al.   CELLULAR MICROBIOLOGY

Hypoxia: a window intoMycobacterium tuberculosislatency

(2009) Tige R. Rustad et al.   CELLULAR MICROBIOLOGY

Mycobacterium tuberculosis modulates its cell surface via an oligopeptide permease (Opp) transport system

(2009) Mario Alberto Flores-Valdez et al.   FASEB JOURNAL

Structural Basis for the Inhibition of Mycobacterium tuberculosis Glutamine Synthetase by Novel ATP-Competitive Inhibitors

(2009) Mikael T. Nilsson et al.   JOURNAL OF MOLECULAR BIOLOGY

The roles of the nitrate reductase NarGHJI, the nitrite reductase NirBD and the response regulator GlnR in nitrate assimilation of Mycobacterium tuberculosis

(2009) S. Malm et al.   MICROBIOLOGY-SGM

Foamy macrophages and the progression of the human tuberculosis granuloma

(2009) David G Russell et al.   NATURE IMMUNOLOGY

Glycine Betaine Uptake by the ProXVWZ ABC Transporter Contributes to the Ability of Mycobacterium tuberculosis To Initiate Growth in Human Macrophages

(2008) C. T. D. Price et al.   JOURNAL OF BACTERIOLOGY

Functional Analysis of GlnE, an Essential Adenylyl Transferase in Mycobacterium tuberculosis

(2008) P. Carroll et al.   JOURNAL OF BACTERIOLOGY

A Genomic View on Nitrogen Metabolism and Nitrogen Control in Mycobacteria

(2008) Johannes Amon et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Nutrient acquisition by mycobacteria

(2008) M. Niederweis   MICROBIOLOGY-SGM

Regulation of glutamate metabolism by protein kinases in mycobacteria

(2008) Helen M. O'Hare et al.   MOLECULAR MICROBIOLOGY

Probing Host Pathogen Cross-Talk by Transcriptional Profiling of Both Mycobacterium tuberculosis and Infected Human Dendritic Cells and Macrophages

(2008) Ludovic Tailleux et al.   PLoS One

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

(2008) Pascale Peyron et al.   PLoS Pathogens

Anaerobic arginine metabolism of Mycobacterium tuberculosis is mediated by arginine deiminase (arcA), but is not essential for chronic persistence in an aerogenic mouse model of infection

(2007) Michael Sürken et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY