Strategies for the discovery and development of therapies for metastatic breast cancer
Published 2012 View Full Article
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Title
Strategies for the discovery and development of therapies for metastatic breast cancer
Authors
Keywords
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Journal
NATURE REVIEWS DRUG DISCOVERY
Volume 11, Issue 6, Pages 479-497
Publisher
Springer Nature
Online
2012-06-01
DOI
10.1038/nrd2372
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Note: Only part of the references are listed.- Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells
- (2014) P. Sinha et al. JOURNAL OF IMMUNOLOGY
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- (2012) N. P. Withana et al. CANCER RESEARCH
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- (2012) Harry D. Bear et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2011) S. Solito et al. BLOOD
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- (2011) F. M. Buffa et al. CANCER RESEARCH
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- (2011) Christopher J Burns et al. EXPERT OPINION ON THERAPEUTIC PATENTS
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- (2011) Bahriye Aktas et al. GYNECOLOGIC ONCOLOGY
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- (2011) Neta Erez et al. INTERNATIONAL JOURNAL OF CANCER
- Microproteomic analysis of 10,000 laser captured microdissected breast tumor cells using short-range sodium dodecyl sulfate-polyacrylamide gel electrophoresis and porous layer open tubular liquid chromatography tandem mass spectrometry
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- Hunk is required for HER2/neu-induced mammary tumorigenesis
- (2011) Elizabeth S. Yeh et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2011) Laetitia A. Mauti et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2011) M. Lorger et al. JOURNAL OF NEURO-ONCOLOGY
- Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study
- (2011) Karen A Gelmon et al. LANCET ONCOLOGY
- Molecular mechanisms and clinical applications of angiogenesis
- (2011) Peter Carmeliet et al. NATURE
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- (2011) Grigory S Filonov et al. NATURE BIOTECHNOLOGY
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- (2011) Yoko S DeRose et al. NATURE MEDICINE
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- (2011) Michaela J. Higgins et al. Nature Reviews Clinical Oncology
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- (2011) T. Luu et al. ONCOLOGIST
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- (2011) F. Fang et al. Science Translational Medicine
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- (2010) L Sevenich et al. ONCOGENE
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- (2009) N. Cabioglu et al. ANNALS OF ONCOLOGY
- Epithelial cell adhesion molecule (EpCAM) is overexpressed in breast cancer metastases
- (2009) Ashley Cimino et al. BREAST CANCER RESEARCH AND TREATMENT
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- (2009) D Canaani BRITISH JOURNAL OF CANCER
- Novel Agents on the Horizon for Cancer Therapy
- (2009) W. W. Ma et al. CA-A CANCER JOURNAL FOR CLINICIANS
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- (2008) C. Marcela Diaz-Montero et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
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- (2008) D. Barkan et al. CANCER RESEARCH
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- (2008) Paola Allavena et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Gene expression predictors in breast cancer: Current status, limitations and perspectives
- (2008) C. Desmedt et al. EUROPEAN JOURNAL OF CANCER
- Micrometastatic disease in breast cancer: Clinical implications
- (2008) Michail Ignatiadis et al. EUROPEAN JOURNAL OF CANCER
- Trial Assessing Individualized Options for Treatment for breast cancer: the TAILORx trial
- (2008) Jo Anne Zujewski et al. Future Oncology
- Review: Biological relevance of disseminated tumor cells in cancer patients
- (2008) Sabine Riethdorf et al. INTERNATIONAL JOURNAL OF CANCER
- Clinical Application of the 70-Gene Profile: The MINDACT Trial
- (2008) Fatima Cardoso et al. JOURNAL OF CLINICAL ONCOLOGY
- Monitoring the Response of Circulating Epithelial Tumor Cells to Adjuvant Chemotherapy in Breast Cancer Allows Detection of Patients at Risk of Early Relapse
- (2008) Katharina Pachmann et al. JOURNAL OF CLINICAL ONCOLOGY
- The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase
- (2008) Sachie Hiratsuka et al. NATURE CELL BIOLOGY
- Tumor Angiogenesis
- (2008) Robert S. Kerbel NEW ENGLAND JOURNAL OF MEDICINE
- MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis
- (2008) L.-X. Yan et al. RNA
- Endothelial Progenitor Cells Control the Angiogenic Switch in Mouse Lung Metastasis
- (2008) D. Gao et al. SCIENCE
- HER2 Status and Efficacy of Adjuvant Anthracyclines in Early Breast Cancer: A Pooled Analysis of Randomized Trials
- (2007) Alessandra Gennari et al. JNCI-Journal of the National Cancer Institute
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