Pulmonary Delivery of siRNA via Polymeric Vectors as Therapies of Asthma

Allergen-Induced Asthmatic Responses Modified by a GATA3-Specific DNAzyme

(2015) Norbert Krug et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tracking and treating activated T cells

(2015) N.H. Kim et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

siRNA Delivery to the lung: What's new?

(2014) Olivia M. Merkel et al.   ADVANCED DRUG DELIVERY REVIEWS

Therapeutic potentials of gene silencing by RNA interference: Principles, challenges, and new strategies

(2014) Yan Deng et al.   GENE

Small Interfering RNAs Targeted to Interleukin-4 and Respiratory Syncytial Virus Reduce Airway Inflammation in a Mouse Model of Virus-Induced Asthma Exacerbation

(2014) Musa R. Khaitov et al.   HUMAN GENE THERAPY

Gene Silencing of SOCS3 by siRNA Intranasal Delivery Inhibits Asthma Phenotype in Mice

(2014) et al.   PLoS One

Folic acid conjugated chitosan for targeted delivery of siRNA to activated macrophages in vitro and in vivo

(2014) Chuanxu Yang et al.   Journal of Materials Chemistry B

Small Interfering RNA Targeting Nerve Growth Factor Alleviates Allergic Airway Hyperresponsiveness

(2014) Yi-Lien Chen et al.   Molecular Therapy-Nucleic Acids

TLR9-mediated siRNA delivery for targeting of normal and malignant human hematopoietic cells in vivo

(2013) Q. Zhang et al.   BLOOD

TRPV1 inhibition attenuates IL-13 mediated asthma features in mice by reducing airway epithelial injury

(2013) Rakhshinda Rehman et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Receptor-Interacting Protein 2 Gene Silencing Attenuates Allergic Airway Inflammation

(2013) F. Y. Goh et al.   JOURNAL OF IMMUNOLOGY

T Cell-Specific siRNA Delivery Using Antibody-Conjugated Chitosan Nanoparticles

(2012) Jangwook Lee et al.   BIOCONJUGATE CHEMISTRY

An inhalable β2-adrenoceptor ligand-directed guanidinylated chitosan carrier for targeted delivery of siRNA to lung

(2012) Yongfeng Luo et al.   JOURNAL OF CONTROLLED RELEASE

Effect of locally administered Syk siRNA on allergen-induced arthritis and asthma

(2012) Zhen-Yu Huang et al.   MOLECULAR IMMUNOLOGY

The alveolar macrophages in asthma: a double-edged sword

(2012) J Balhara et al.   Mucosal Immunology

The potential of biologics for the treatment of asthma

(2012) Girolamo Pelaia et al.   NATURE REVIEWS DRUG DISCOVERY

Regulation of mucosal mast cell activation by short interfering RNAs targeting syntaxin4

(2011) Shuang Liu et al.   IMMUNOLOGY AND CELL BIOLOGY

An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation

(2011) R. Yagi et al.   INTERNATIONAL IMMUNOLOGY

Controlled pulmonary drug and gene delivery using polymeric nano-carriers

(2011) Moritz Beck-Broichsitter et al.   JOURNAL OF CONTROLLED RELEASE

Progress Toward In Vivo Use of siRNAs-II

(2011) Garrett R Rettig et al.   MOLECULAR THERAPY

Spleen tyrosine kinases: biology, therapeutic targets and drugs

(2010) Mauro Riccaboni et al.   DRUG DISCOVERY TODAY

Targeted Delivery of siRNA to Macrophages for Anti-inflammatory Treatment

(2010) Sang-Soo Kim et al.   MOLECULAR THERAPY

New therapies for asthma: is there any progress?

(2010) Peter J. Barnes   TRENDS IN PHARMACOLOGICAL SCIENCES

Inhibition of allergic responses by CD40 gene silencing

(2009) M. Suzuki et al.   ALLERGY

A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation

(2009) X. Zheng et al.   BLOOD

Influence of comorbid conditions on asthma

(2009) L-P. Boulet   EUROPEAN RESPIRATORY JOURNAL

Small Interfering RNA against Transcription Factor STAT6 Inhibits Allergic Airway Inflammation and Hyperreactivity in Mice

(2009) Y. Darcan-Nicolaisen et al.   JOURNAL OF IMMUNOLOGY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

(2008) Priti Kumar et al.   CELL

Small interfering RNA against interleukin-5 decreases airway eosinophilia and hyper-responsiveness

(2008) H-Y Huang et al.   GENE THERAPY

Effective prevention and therapy of experimental allergic asthma using a GATA-3–specific DNAzyme

(2008) Serdar Sel et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Targeting the NF-κB pathway in asthma and chronic obstructive pulmonary disease

(2008) Michael R. Edwards et al.   PHARMACOLOGY & THERAPEUTICS

Lentiviral-mediated GATA-3 RNAi Decreases Allergic Airway Inflammation and Hyperresponsiveness

(2007) Chen-Chen Lee et al.   MOLECULAR THERAPY