Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Role of Amygdala Central Nucleus in Aversive Learning Produced by Shock or by Unexpected Omission of Food

(2012) R. J. Purgert et al.   JOURNAL OF NEUROSCIENCE

Amygdala Central Nucleus Interacts with Dorsolateral Striatum to Regulate the Acquisition of Habits

(2012) N. W. Lingawi et al.   JOURNAL OF NEUROSCIENCE

A Memory Retrieval-Extinction Procedure to Prevent Drug Craving and Relapse

(2012) Y.-X. Xue et al.   SCIENCE

Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization

(2011) Jeffrey Bailey et al.   ADDICTION BIOLOGY

Impairment of object recognition memory by rapamycin inhibition of mTOR in the amygdala or hippocampus around the time of learning or reactivation

(2011) Paulo F.C. Jobim et al.   BEHAVIOURAL BRAIN RESEARCH

PSD-95-like membrane associated guanylate kinases (PSD-MAGUKs) and synaptic plasticity

(2011) Weifeng Xu   CURRENT OPINION IN NEUROBIOLOGY

Local RNA Translation at the Synapse and in Disease

(2011) L. Liu-Yesucevitz et al.   JOURNAL OF NEUROSCIENCE

Glial Cell Line-Derived Neurotrophic Factor Reverses Alcohol-Induced Allostasis of the Mesolimbic Dopaminergic System: Implications for Alcohol Reward and Seeking

(2011) S. Barak et al.   JOURNAL OF NEUROSCIENCE

Inhibition of mTOR by rapamycin in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory

(2011) Paulo F.C. Jobim et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Consolidation and reconsolidation of contextual fear memory requires mammalian target of rapamycin-dependent translation in the dorsal hippocampus

(2011) G.M. Gafford et al.   NEUROSCIENCE

Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage

(2011) Loredana Stoica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antagonism at NMDA receptors, but not β-adrenergic receptors, disrupts the reconsolidation of pavlovian conditioned approach and instrumental transfer for ethanol-associated conditioned stimuli

(2011) Amy L. Milton et al.   PSYCHOPHARMACOLOGY

Arc in synaptic plasticity: from gene to behavior

(2011) Erica Korb et al.   TRENDS IN NEUROSCIENCES

Neurobiology of the incubation of drug craving

(2011) Charles L. Pickens et al.   TRENDS IN NEUROSCIENCES

New Findings on Biological Factors Predicting Addiction Relapse Vulnerability

(2011) Rajita Sinha   Current Psychiatry Reports

Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption

(2011) S Barak et al.   Translational Psychiatry

Nucleus Accumbens Core Mammalian Target of Rapamycin Signaling Pathway Is Critical for Cue-Induced Reinstatement of Cocaine Seeking in Rats

(2010) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Long-Lasting Adaptations of the NR2B-Containing NMDA Receptors in the Dorsomedial Striatum Play a Crucial Role in Alcohol Consumption and Relapse

(2010) J. Wang et al.   JOURNAL OF NEUROSCIENCE

Differing effects of systemically administered rapamycin on consolidation and reconsolidation of context vs. cued fear memories

(2010) E. M. Glover et al.   LEARNING & MEMORY

Reduced Nucleus Accumbens SK Channel Activity Enhances Alcohol Seeking during Abstinence

(2010) F. Woodward Hopf et al.   NEURON

Neural Correlates of Variations in Event Processing during Learning in Central Nucleus of Amygdala

(2010) Donna J. Calu et al.   NEURON

Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders

(2010) J. Neasta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Spatially restricting gene expression by local translation at synapses

(2010) Dan Ohtan Wang et al.   TRENDS IN NEUROSCIENCES

Excessive alcohol consumption is blocked by glial cell line–derived neurotrophic factor

(2009) Sebastien Carnicella et al.   ALCOHOL

Metabotropic Glutamate Receptor 5 Activity in the Nucleus Accumbens Is Required for the Maintenance of Ethanol Self-Administration in a Rat Genetic Model of High Alcohol Intake

(2009) Joyce Besheer et al.   BIOLOGICAL PSYCHIATRY

Which Cue to "Want?" Central Amygdala Opioid Activation Enhances and Focuses Incentive Salience on a Prepotent Reward Cue

(2009) S. V. Mahler et al.   JOURNAL OF NEUROSCIENCE

Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling

(2009) Emma Puighermanal et al.   NATURE NEUROSCIENCE

A single standard for memory: the case for reconsolidation

(2009) Karim Nader et al.   NATURE REVIEWS NEUROSCIENCE

Translational Control of Long-Lasting Synaptic Plasticity and Memory

(2009) Mauro Costa-Mattioli et al.   NEURON

Phasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety

(2009) Michael Davis et al.   NEUROPSYCHOPHARMACOLOGY

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidation

(2008) Jacqueline Blundell et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse

(2008) S. Carnicella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Update on neuropharmacological treatments for alcoholism: Scientific basis and clinical findings

(2007) Bankole A. Johnson   BIOCHEMICAL PHARMACOLOGY