Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders

Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau

(2010) Antonella Caccamo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

(2010) Patricia Spilman et al.   PLoS One

Spatially restricting gene expression by local translation at synapses

(2010) Dan Ohtan Wang et al.   TRENDS IN NEUROSCIENCES

Temsirolimus in patients with advanced renal cell carcinoma: an overview

(2009) Shailender Bhatia et al.   ADVANCES IN THERAPY

Excessive alcohol consumption is blocked by glial cell line–derived neurotrophic factor

(2009) Sebastien Carnicella et al.   ALCOHOL

Dissecting the role of mTOR: Lessons from mTOR inhibitors

(2009) Ryan J.O. Dowling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

Glutamate and reinstatement

(2009) Lori A Knackstedt et al.   CURRENT OPINION IN PHARMACOLOGY

Binge Drinking Upregulates Accumbens mGluR5-Homer2-PI3K Signaling: Functional Implications for Alcoholism

(2009) D. K. Cozzoli et al.   JOURNAL OF NEUROSCIENCE

Rapamycin Protects Against High Fat Diet–Induced Obesity in C57BL/6J Mice

(2009) Geng-Ruei Chang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling

(2009) Emma Puighermanal et al.   NATURE NEUROSCIENCE

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Translational Control of Long-Lasting Synaptic Plasticity and Memory

(2009) Mauro Costa-Mattioli et al.   NEURON

Neurocircuitry of Addiction

(2009) George F Koob et al.   NEUROPSYCHOPHARMACOLOGY

Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior

(2009) Rainer Spanagel   PHYSIOLOGICAL REVIEWS

BDNF Activates mTOR to Regulate GluR1 Expression Required for Memory Formation

(2009) Leandro Slipczuk et al.   PLoS One

Immunosuppression Using the Mammalian Target of Rapamycin (mTOR) Inhibitor Everolimus: Pilot Study Shows Significant Cognitive and Affective Improvement

(2009) U.E. Lang et al.   TRANSPLANTATION PROCEEDINGS

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Drinking Typography Established by Scheduled Induction Predicts Chronic Heavy Drinking in a Monkey Model of Ethanol Self-Administration

(2008) Kathleen A. Grant et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidation

(2008) Jacqueline Blundell et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Involvement of Amygdala Dopamine and Nucleus Accumbens NMDA Receptors in Ethanol-Seeking Behavior in Mice

(2008) Christina M Gremel et al.   NEUROPSYCHOPHARMACOLOGY

Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis

(2008) John J. Bissler et al.   NEW ENGLAND JOURNAL OF MEDICINE

GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse

(2008) S. Carnicella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Addiction and the Brain Antireward System

(2007) George F. Koob et al.   Annual Review of Psychology

Homers regulate drug-induced neuroplasticity: Implications for addiction

(2007) Karen K. Szumlinski et al.   BIOCHEMICAL PHARMACOLOGY