From genes to protein mechanics on a chip

Protein–DNA force assay in a microfluidic format

(2013) Marcus Otten et al.   LAB ON A CHIP

Multiplexed surface micropatterning of proteins with a pressure-modulated microfluidic button-membrane

(2012) Jose L. Garcia-Cordero et al.   CHEMICAL COMMUNICATIONS

iSLIM: a comprehensive approach to mapping and characterizing gene regulatory networks

(2012) Sylvie Rockel et al.   NUCLEIC ACIDS RESEARCH

Single-molecule dissection of the high-affinity cohesin-dockerin complex

(2012) S. W. Stahl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thiol-based, site-specific and covalent immobilization of biomolecules for single-molecule experiments

(2010) Julia L Zimmermann et al.   Nature Protocols

Force probing surfaces of living cells to molecular resolution

(2009) Daniel J Müller et al.   Nature Chemical Biology

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Ultrastable combined atomic force and total internal fluorescence microscope

(2009) H. Gumpp et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Comparing Proteins by Their Unfolding Pattern

(2008) Elias M. Puchner et al.   BIOPHYSICAL JOURNAL

Single-Molecule Force Spectroscopy Reveals a Stepwise Unfolding of Caenorhabditis elegans Giant Protein Kinase Domains

(2008) Dina N. Greene et al.   BIOPHYSICAL JOURNAL

An in vitro microfluidic approach to generating protein-interaction networks

(2008) Doron Gerber et al.   NATURE METHODS