Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines

Revealing the role of CD4+T cells in viral immunity: Figure 1.

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Spatial Alterations between CD4+ T Follicular Helper, B, and CD8+ T Cells during Simian Immunodeficiency Virus Infection: T/B Cell Homeostasis, Activation, and Potential Mechanism for Viral Escape

(2012) J. J. Hong et al.   JOURNAL OF IMMUNOLOGY

Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

(2012) Dan H. Barouch et al.   NATURE

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

(2012) Barton F. Haynes et al.   NEW ENGLAND JOURNAL OF MEDICINE

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(2011) Shane Crotty   Annual Review of Immunology

New Paradigms for HIV/AIDS Vaccine Development

(2011) Louis J. Picker et al.   Annual Review of Medicine

CD4+ memory T cell survival

(2011) Justin J Taylor et al.   CURRENT OPINION IN IMMUNOLOGY

High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses

(2011) Justin Pollara et al.   CYTOMETRY PART A

Tight Regulation of Memory CD8+ T Cells Limits Their Effectiveness during Sustained High Viral Load

(2011) Erin E. West et al.   IMMUNITY

Interaction Patches of Procaspase-1 Caspase Recruitment Domains (CARDs) Are Differently Involved in Procaspase-1 Activation and Receptor-interacting Protein 2 (RIP2)-dependent Nuclear Factor κB Signaling

(2011) Kristof Kersse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

(2011) Marina Caskey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Development and implementation of an international proficiency testing program for a neutralizing antibody assay for HIV-1 in TZM-bl cells

(2011) Christopher A. Todd et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

Early Events in Sexual Transmission of HIV and SIV and Opportunities for Interventions

(2010) Ashley T. Haase   Annual Review of Medicine

T-Cell Correlates of Vaccine Efficacy after a Heterologous Simian Immunodeficiency Virus Challenge

(2010) M. A. Martins et al.   JOURNAL OF VIROLOGY

Macaques Vaccinated with Simian Immunodeficiency Virus SIVmac239 nef Delay Acquisition and Control Replication after Repeated Low-Dose Heterologous SIV Challenge

(2010) M. R. Reynolds et al.   JOURNAL OF VIROLOGY

Protection of Macaques with Diverse MHC Genotypes against a Heterologous SIV by Vaccination with a Deglycosylated Live-Attenuated SIV

(2010) Chie Sugimoto et al.   PLoS One

TRIM5 Suppresses Cross-Species Transmission of a Primate Immunodeficiency Virus and Selects for Emergence of Resistant Variants in the New Species

(2010) Andrea Kirmaier et al.   PLOS BIOLOGY

Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12

(2009) Cindy S Ma et al.   IMMUNOLOGY AND CELL BIOLOGY

Inhibitory TCR Coreceptor PD-1 Is a Sensitive Indicator of Low-Level Replication of SIV and HIV-1

(2009) Nadine C. Salisch et al.   JOURNAL OF IMMUNOLOGY

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

(2009) Scott G Hansen et al.   NATURE MEDICINE

Gag- and Nef-specific CD4+ T cells recognize and inhibit SIV replication in infected macrophages early after infection

(2009) J. B. Sacha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunization with Single-Cycle SIV Significantly Reduces Viral Loads After an Intravenous Challenge with SIVmac239

(2009) Bin Jia et al.   PLoS Pathogens

Longitudinal in Vivo Positron Emission Tomography Imaging of Infected and Activated Brain Macrophages in a Macaque Model of Human Immunodeficiency Virus Encephalitis Correlates with Central and Peripheral Markers of Encephalitis and Areas of Synaptic Degeneration

(2008) Sriram Venneti et al.   AMERICAN JOURNAL OF PATHOLOGY

Distinct regulation of effector and memory T-cell differentiation

(2008) Axel Kallies   IMMUNOLOGY AND CELL BIOLOGY

Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

(2008) Matthew R. Reynolds et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vaccine Protection by Live, Attenuated Simian Immunodeficiency Virus in the Absence of High-Titer Antibody Responses and High-Frequency Cellular Immune Responses Measurable in the Periphery

(2008) K. Mansfield et al.   JOURNAL OF VIROLOGY

With Minimal Systemic T-Cell Expansion, CD8+ T Cells Mediate Protection of Rhesus Macaques Immunized with Attenuated Simian-Human Immunodeficiency Virus SHIV89.6 from Vaginal Challenge with Simian Immunodeficiency Virus

(2008) M. Genesca et al.   JOURNAL OF VIROLOGY

Memory CD8 T-cell compartment grows in size with immunological experience

(2008) Vaiva Vezys et al.   NATURE

Pathogenic mechanisms in simian immunodeficiency virus infection

(2008) Zvi Grossman et al.   Current Opinion in HIV and AIDS