Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis

Nod-like receptors in the control of intestinal inflammation

(2012) Stephen J Rubino et al.   CURRENT OPINION IN IMMUNOLOGY

The Sphingosine-1-Phosphate Analogue FTY720 Impairs Mucosal Immunity and Clearance of the Enteric Pathogen Citrobacter rodentium

(2012) Carola T. Murphy et al.   INFECTION AND IMMUNITY

The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

(2012) Rune Busk Damgaard et al.   MOLECULAR CELL

Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons

(2012) Jakub Siednienko et al.   NATURE IMMUNOLOGY

Notch Signaling

(2012) R. Kopan   Cold Spring Harbor Perspectives in Biology

The role of TBK1 and IKKϵ in the expression and activation of Pellino 1

(2011) Hilary Smith et al.   BIOCHEMICAL JOURNAL

Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system

(2011) Eddy T. H. Goh et al.   BIOCHEMICAL JOURNAL

The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes

(2011) Yun-Gi Kim et al.   IMMUNITY

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Peli1 (rel)ieves autoimmunity

(2011) Paul N Moynagh   NATURE IMMUNOLOGY

Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity

(2011) Ya-Jen Chang et al.   NATURE IMMUNOLOGY

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

(2011) Kaoru Geddes et al.   NATURE MEDICINE

cIAP1/2 Are Direct E3 Ligases Conjugating Diverse Types of Ubiquitin Chains to Receptor Interacting Proteins Kinases 1 to 4 (RIP1–4)

(2011) Mathieu J. M. Bertrand et al.   PLoS One

ITCH K63-Ubiquitinates the NOD2 Binding Protein, RIP2, to Influence Inflammatory Signaling Pathways

(2009) MingFang Tao et al.   CURRENT BIOLOGY

Cellular Inhibitors of Apoptosis cIAP1 and cIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2

(2009) Mathieu J.M. Bertrand et al.   IMMUNITY

Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction

(2009) Tobias L. Haas et al.   MOLECULAR CELL

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

(2009) Mikyoung Chang et al.   NATURE IMMUNOLOGY

Identification of the phosphorylation sites on the E3 ubiquitin ligase Pellino that are critical for activation by IRAK1 and IRAK4

(2009) H. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ubiquitin-Editing Enzyme A20 Restricts Nucleotide-Binding Oligomerization Domain Containing 2-Triggered Signals

(2008) Osamu Hitotsumatsu et al.   IMMUNITY

Pellino Proteins Contain a Cryptic FHA Domain that Mediates Interaction with Phosphorylated IRAK1

(2008) Chun-Chi Lin et al.   STRUCTURE

The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling

(2008) Paul N. Moynagh   TRENDS IN IMMUNOLOGY

The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1

(2007) Alban Ordureau et al.   BIOCHEMICAL JOURNAL