Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3- and viral-induced expression of type I interferons

The role of TBK1 and IKKϵ in the expression and activation of Pellino 1

(2011) Hilary Smith et al.   BIOCHEMICAL JOURNAL

Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system

(2011) Eddy T. H. Goh et al.   BIOCHEMICAL JOURNAL

Mal Mediates TLR-Induced Activation of CREB and Expression of IL-10

(2011) M. Mellett et al.   JOURNAL OF IMMUNOLOGY

Interferons in Autoimmune and Inflammatory Diseases: Regulation and Roles

(2011) Divaker Choubey et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Peli1 (rel)ieves autoimmunity

(2011) Paul N Moynagh   NATURE IMMUNOLOGY

Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity

(2011) Ya-Jen Chang et al.   NATURE IMMUNOLOGY

Direct binding of TRAF2 and TRAF6 to TICAM-1/TRIF adaptor participates in activation of the Toll-like receptor 3/4 pathway

(2010) Miwa Sasai et al.   MOLECULAR IMMUNOLOGY

Pellino-1, an adaptor protein of interleukin-1 receptor/toll-like receptor signaling, is sumoylated by Ubc9

(2010) Jun Hwan Kim et al.   MOLECULES AND CELLS

Thogoto virus ML protein is a potent inhibitor of the interferon regulatory factor-7 transcription factor

(2009) N. Buettner et al.   JOURNAL OF GENERAL VIROLOGY

Direct activation of protein kinases by unanchored polyubiquitin chains

(2009) Zong-Ping Xia et al.   NATURE

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

(2009) Mikyoung Chang et al.   NATURE IMMUNOLOGY

TRAF6 Establishes Innate Immune Responses by Activating NF-κB and IRF7 upon Sensing Cytosolic Viral RNA and DNA

(2009) Hiroyasu Konno et al.   PLoS One

Identification of the phosphorylation sites on the E3 ubiquitin ligase Pellino that are critical for activation by IRAK1 and IRAK4

(2009) H. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRAF6 and the Three C-Terminal Lysine Sites on IRF7 Are Required for Its Ubiquitination-Mediated Activation by the Tumor Necrosis Factor Receptor Family Member Latent Membrane Protein 1

(2008) S. Ning et al.   MOLECULAR AND CELLULAR BIOLOGY

TRAF6 Autoubiquitination-Independent Activation of the NFκB and MAPK Pathways in Response to IL-1 and RANKL

(2008) Matthew C. Walsh et al.   PLoS One

Pellino Proteins Contain a Cryptic FHA Domain that Mediates Interaction with Phosphorylated IRAK1

(2008) Chun-Chi Lin et al.   STRUCTURE

The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling

(2008) Paul N. Moynagh   TRENDS IN IMMUNOLOGY

The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1

(2007) Alban Ordureau et al.   BIOCHEMICAL JOURNAL