High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability

Human demographic history has amplified the effects of background selection across the genome

(2018) Raul Torres et al.   PLoS Genetics

Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection

(2017) Steven Gazal et al.   NATURE GENETICS

Background selection as null hypothesis in population genomics: insights and challenges from Drosophila studies

(2017) Josep M. Comeron   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Population Structure of UK Biobank and Ancient Eurasians Reveals Adaptation at Genes Influencing Blood Pressure

(2016) Kevin J. Galinsky et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ARGON: fast, whole-genome simulation of the discrete time Wright-fisher process

(2016) Pier Francesco Palamara   BIOINFORMATICS

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

Fast and accurate long-range phasing in a UK Biobank cohort

(2016) Po-Ru Loh et al.   NATURE GENETICS

Robust and scalable inference of population history from hundreds of unphased whole genomes

(2016) Jonathan Terhorst et al.   NATURE GENETICS

Detection of human adaptation during the past 2000 years

(2016) Yair Field et al.   SCIENCE

Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates

(2015) Pier Francesco Palamara et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Accurate Non-parametric Estimation of Recent Effective Population Size from Segments of Identity by Descent

(2015) Sharon R. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Aberrant Time to Most Recent Common Ancestor as a Signature of Natural Selection

(2015) Haley Hunter-Zinck et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome-wide patterns of selection in 230 ancient Eurasians

(2015) Iain Mathieson et al.   NATURE

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

Large-scale whole-genome sequencing of the Icelandic population

(2015) Daniel F Gudbjartsson et al.   NATURE GENETICS

Genomic evidence for the Pleistocene and recent population history of Native Americans

(2015) M. Raghavan et al.   SCIENCE

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

minimac2: faster genotype imputation

(2014) Christian Fuchsberger et al.   BIOINFORMATICS

Genome-wide signals of positive selection in human evolution

(2014) D. Enard et al.   GENOME RESEARCH

The genomic landscape of Neanderthal ancestry in present-day humans

(2014) Sriram Sankararaman et al.   NATURE

Inferring human population size and separation history from multiple genome sequences

(2014) Stephan Schiffels et al.   NATURE GENETICS

Resurrecting Surviving Neandertal Lineages from Modern Human Genomes

(2014) B. Vernot et al.   SCIENCE

Markovian approximation to the finite loci coalescent with recombination along multiple sequences

(2014) Asger Hobolth et al.   THEORETICAL POPULATION BIOLOGY

Demography and the Age of Rare Variants

(2014) Iain Mathieson et al.   PLoS Genetics

Genome-Wide Inference of Ancestral Recombination Graphs

(2014) Matthew D. Rasmussen et al.   PLoS Genetics

Detecting Identity by Descent and Estimating Genotype Error Rates in Sequence Data

(2013) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Estimating Variable Effective Population Sizes from Multiple Genomes: A Sequentially Markov Conditional Sampling Distribution Approach

(2013) S. Sheehan et al.   GENETICS

Improving the Accuracy and Efficiency of Identity-by-Descent Detection in Population Data

(2013) B. L. Browning et al.   GENETICS

Background Selection 20 Years on

(2013) Brian Charlesworth   JOURNAL OF HEREDITY

The complete genome sequence of a Neanderthal from the Altai Mountains

(2013) Kay Prüfer et al.   NATURE

dbPSHP: a database of recent positive selection across human populations

(2013) Mulin Jun Li et al.   NUCLEIC ACIDS RESEARCH

The Geography of Recent Genetic Ancestry across Europe

(2013) Peter Ralph et al.   PLOS BIOLOGY

Length Distributions of Identity by Descent Reveal Fine-Scale Demographic History

(2012) Pier Francesco Palamara et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The role of annexin A3 playing in cancers

(2012) Na Wu et al.   Clinical & Translational Oncology

Association of STAT4 rs7574865 polymorphism with autoimmune diseases: a meta-analysis

(2012) Ya-ling Liang et al.   MOLECULAR BIOLOGY REPORTS

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

(2012) Yukinori Okada et al.   NATURE GENETICS

Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes

(2012) J. A. Tennessen et al.   SCIENCE

Human Evolution Out of Africa: The Role of Refugia and Climate Change

(2012) J. R. Stewart et al.   SCIENCE

DASH: A Method for Identical-by-Descent Haplotype Mapping Uncovers Association with Recent Variation

(2011) Alexander Gusev et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Crohn's Disease and Genetic Hitchhiking at IBD5

(2011) C. D. Huff et al.   MOLECULAR BIOLOGY AND EVOLUTION

Inference of human population history from individual whole-genome sequences

(2011) Heng Li et al.   NATURE

The landscape of recombination in African Americans

(2011) Anjali G. Hinch et al.   NATURE

Recombination rates in admixed individuals identified by ancestry-based inference

(2011) Daniel Wegmann et al.   NATURE GENETICS

A CommonMUC5BPromoter Polymorphism and Pulmonary Fibrosis

(2011) Max A. Seibold et al.   NEW ENGLAND JOURNAL OF MEDICINE

Classic Selective Sweeps Were Rare in Recent Human Evolution

(2011) R. D. Hernandez et al.   SCIENCE

The Neutral Theory of Molecular Evolution in the Genomic Era

(2010) Masatoshi Nei et al.   Annual Review of Genomics and Human Genetics

The Genetics of Human Adaptation: Hard Sweeps, Soft Sweeps, and Polygenic Adaptation

(2010) Jonathan K. Pritchard et al.   CURRENT BIOLOGY

Interaction between PKD1L3 and PKD2L1 through their transmembrane domains is required for localization of PKD2L1 at taste pores in taste cells of circumvallate and foliate papillae

(2010) Yoshiro Ishimaru et al.   FASEB JOURNAL

SNP detection and genotyping from low-coverage sequencing data on multiple diploid samples

(2010) S. Q. Le et al.   GENOME RESEARCH

Fine-scale recombination rate differences between sexes, populations and individuals

(2010) Augustine Kong et al.   NATURE

A Draft Sequence of the Neandertal Genome

(2010) R. E. Green et al.   SCIENCE

From evolutionary genetics to human immunology: how selection shapes host defence genes

(2009) Luis B. Barreiro et al.   NATURE REVIEWS GENETICS

Widespread Genomic Signatures of Natural Selection in Hominid Evolution

(2009) Graham McVicker et al.   PLoS Genetics

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

A Single SNP in an Evolutionary Conserved Region within Intron 86 of the HERC2 Gene Determines Human Blue-Brown Eye Color

(2008) Richard A. Sturm et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association ofSTAT4with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population

(2008) Shu Kobayashi et al.   ARTHRITIS AND RHEUMATISM

STAT4: Genetics, mechanisms, and implications for autoimmunity

(2008) Benjamin D. Korman et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Detection of sharing by descent, long-range phasing and haplotype imputation

(2008) Augustine Kong et al.   NATURE GENETICS