Crohn's Disease and Genetic Hitchhiking at IBD5

Detecting positive selection from genome scans of linkage disequilibrium

(2010) Chad D Huff et al.   BMC GENOMICS

Toward a more uniform sampling of human genetic diversity: A survey of worldwide populations by high-density genotyping

(2010) Jinchuan Xing et al.   GENOMICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

A Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive Selection

(2010) S. R. Grossman et al.   SCIENCE

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

A Predominantly Neolithic Origin for European Paternal Lineages

(2010) Patricia Balaresque et al.   PLOS BIOLOGY

The unusual amino acid L-ergothioneine is a physiologic cytoprotectant

(2009) B D Paul et al.   CELL DEATH AND DIFFERENTIATION

Skin cells and tissue are capable of using l-ergothioneine as an integral component of their antioxidant defense system

(2009) Nelli G. Markova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gene Genealogies Strongly Distorted by Weakly Interfering Mutations in Constant Environments

(2009) J. Seger et al.   GENETICS

Fine-scaled human genetic structure revealed by SNP microarrays

(2009) J. Xing et al.   GENOME RESEARCH

Signals of recent positive selection in a worldwide sample of human populations

(2009) J. K. Pickrell et al.   GENOME RESEARCH

Common variants at five new loci associated with early-onset inflammatory bowel disease

(2009) Marcin Imielinski et al.   NATURE GENETICS

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Natural Selection on Genes that Underlie Human Disease Susceptibility

(2008) Ran Blekhman et al.   CURRENT BIOLOGY

Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation

(2008) J. Z. Li et al.   SCIENCE