SnAP reagents for the one-step synthesis of medium-ring saturated N-heterocycles from aldehydes

Asymmetric Hydroamination: A Survey of the Most Recent Developments

(2013) Jérôme Hannedouche et al.   CHEMISTRY-A EUROPEAN JOURNAL

SnAP Reagents for the Transformation of Aldehydes into Substituted Thiomorpholines-An Alternative to Cross-Coupling with Saturated Heterocycles

(2012) Cam-Van T. Vo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct α-Functionalization of Saturated Cyclic Amines

(2012) Emily A. Mitchell et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Developments in Palladium-Catalyzed Alkene Aminoarylation Reactions for the Synthesis of Nitrogen Heterocycles

(2012) John Wolfe et al.   SYNTHESIS-STUTTGART

Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety

(2011) Nicholas A. Meanwell   CHEMICAL RESEARCH IN TOXICOLOGY

Synthesis of Saturated 1,4-Benzodiazepines via Pd-Catalyzed Carboamination Reactions.

(2011) Joshua D. Neukom et al.   ORGANIC LETTERS

The impact of aromatic ring count on compound developability: further insights by examining carbo- and hetero-aromatic and -aliphatic ring types

(2010) Timothy J. Ritchie et al.   DRUG DISCOVERY TODAY

Iron-Catalyzed C−C Bond Formation at α-Position of Aliphatic Amines via C−H Bond Activation through 1,5-Hydrogen Transfer

(2010) Naohiko Yoshikai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Impact of ion class and time on oral drug molecular properties

(2010) Paul D. Leeson et al.   MedChemComm

The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?

(2009) Timothy J. Ritchie et al.   DRUG DISCOVERY TODAY

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Expedite Protocol for Construction of Chiral Regioselectively N-Protected Monosubstituted Piperazine, 1,4-Diazepane, and 1,4-Diazocane Building Blocks

(2009) François Crestey et al.   JOURNAL OF ORGANIC CHEMISTRY

Practical Aspects of Carbon−Carbon Cross-Coupling Reactions Using Heteroarenes

(2009) Vincent F. Slagt et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Hydroamination: Direct Addition of Amines to Alkenes and Alkynes

(2008) Thomas E. Müller et al.   CHEMICAL REVIEWS

Synthesis of 2-Arylpiperidines by Palladium Couplings of Aryl Bromides with Organozinc Species Derived from Deprotonation ofN-Boc-Piperidine

(2008) Iain Coldham et al.   ORGANIC LETTERS