A microbial biomanufacturing platform for natural and semisynthetic opioids

Improvement of Reticuline Productivity from Dopamine by Using EngineeredEscherichia coli

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Dioxygenases CatalyzeO-Demethylation andO,O-Demethylenation with Widespread Roles in Benzylisoquinoline Alkaloid Metabolism in Opium Poppy

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Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols

(2013) José L Avalos et al.   NATURE BIOTECHNOLOGY

Benzylisoquinoline Alkaloid Metabolism: A Century of Discovery and a Brave New World

(2013) Jillian M. Hagel et al.   PLANT AND CELL PHYSIOLOGY

Morphine Biosynthesis in Opium Poppy Involves Two Cell Types: Sieve Elements and Laticifers

(2013) A. Onoyovwe et al.   PLANT CELL

Bench-top fermentative production of plant benzylisoquinoline alkaloids using a bacterial platform

(2012) Akira Nakagawa et al.   Bioengineered

Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools

(2011) Michael S. Siddiqui et al.   FEMS YEAST RESEARCH

Harnessing yeast subcellular compartments for the production of plant terpenoids

(2011) Moran Farhi et al.   METABOLIC ENGINEERING

DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

(2011) Robert J. Conrado et al.   NUCLEIC ACIDS RESEARCH

Systematic knockdown of morphine pathway enzymes in opium poppy using virus-induced gene silencing

(2011) Champa P. Wijekoon et al.   PLANT JOURNAL

Organization of Intracellular Reactions with Rationally Designed RNA Assemblies

(2011) C. J. Delebecque et al.   SCIENCE

A bacterial platform for fermentative production of plant alkaloids

(2011) Akira Nakagawa et al.   Nature Communications

Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli

(2010) Tae Seok Moon et al.   METABOLIC ENGINEERING

Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy

(2010) Jillian M Hagel et al.   Nature Chemical Biology

Synthesis of Methyl Halides from Biomass Using Engineered Microbes

(2009) Travis S. Bayer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

Targeted metabolite and transcript profiling for elucidating enzyme function: isolation of novelN-methyltransferases from three benzylisoquinoline alkaloid-producing species

(2009) David K. Liscombe et al.   PLANT JOURNAL

Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae

(2008) Kristy M Hawkins et al.   Nature Chemical Biology

Microbial production of plant benzylisoquinoline alkaloids

(2008) H. Minami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA