标题
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
作者
关键词
-
出版物
Nature Chemical Biology
Volume 8, Issue 4, Pages 393-399
出版商
Springer Nature
发表日期
2012-02-27
DOI
10.1038/nchembio.797
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Functional Screening of Alzheimer Pathology Genome-wide Association Signals in Drosophila
- (2011) Joshua M. Shulman et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Targeting Post-translational Modifications on Tau as a Therapeutic Strategy for Alzheimer's Disease
- (2011) Jacob Newman Marcus et al. JOURNAL OF NEUROGENETICS
- Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation
- (2011) Caroline Smet-Nocca et al. Molecular BioSystems
- Protein Native-State Stabilization by Placing Aromatic Side Chains in N-Glycosylated Reverse Turns
- (2011) E. K. Culyba et al. SCIENCE
- Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody
- (2010) Scott A. Yuzwa et al. AMINO ACIDS
- Elevation of Global O-GlcNAc in Rodents Using a Selective O-GlcNAcase Inhibitor Does Not Cause Insulin Resistance or Perturb Glucohomeostasis
- (2010) Matthew S. Macauley et al. CHEMISTRY & BIOLOGY
- Caspase activation precedes and leads to tangles
- (2010) Alix de Calignon et al. NATURE
- Dysregulation of the nutrient/stress sensor O-GlcNAcylation is involved in the etiology of cardiovascular disorders, type-2 diabetes and Alzheimer's disease
- (2009) Tony Lefebvre et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease
- (2009) F. Liu et al. BRAIN
- Efficacy of a novel, orally active GSK-3 inhibitor 6-Methyl-N-[3-[[3-(1-methylethoxy)propyl]carbamoyl]-1H-pyrazol-4-yl]pyridine-3-carboxamide in tau transgenic mice
- (2009) Yumiko Uno et al. BRAIN RESEARCH
- Brain glucose transporters,O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer’s disease
- (2009) Ying Liu et al. JOURNAL OF NEUROCHEMISTRY
- Enrichment and Site Mapping ofO-LinkedN-Acetylglucosamine by a Combination of Chemical/Enzymatic Tagging, Photochemical Cleavage, and Electron Transfer Dissociation Mass Spectrometry
- (2009) Zihao Wang et al. MOLECULAR & CELLULAR PROTEOMICS
- The core trisaccharide of an N-linked glycoprotein intrinsically accelerates folding and enhances stability
- (2009) S. R. Hanson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural insights into mechanism and specificity of O-GlcNAc transferase
- (2008) Andrew J Clarke et al. EMBO JOURNAL
- A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo
- (2008) Scott A Yuzwa et al. Nature Chemical Biology
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